Methyl 3-amino-4-methylthiophene-2-carboxylate
- Product Name
- Methyl 3-amino-4-methylthiophene-2-carboxylate
- CAS No.
- 85006-31-1
- Chemical Name
- Methyl 3-amino-4-methylthiophene-2-carboxylate
- Synonyms
- 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER;3-Amino Articaine;3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER;M3A4MT2C;Articaine-002;Articaine Impurity I;Articaine Impurity 9;LABOTEST-BB LT00453517;Articaine EP Impurity I;Articaine intermediate E
- CBNumber
- CB0189112
- Molecular Formula
- C7H9NO2S
- Formula Weight
- 171.22
- MOL File
- 85006-31-1.mol
Methyl 3-amino-4-methylthiophene-2-carboxylate Property
- Melting point:
- 85-88 °C (lit.)
- Boiling point:
- 318.6±37.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- Flash point:
- >100°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 1.71±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow
- Water Solubility
- 1g/L at 35℃
- BRN
- 973196
- InChIKey
- YICRPERKKBDRSP-UHFFFAOYSA-N
- LogP
- 1.28
- CAS DataBase Reference
- 85006-31-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25-22
- WGK Germany
- 2
- Hazard Note
- Irritant
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 546658
- Product name
- Methyl 3-amino-4-methylthiophene-2-carboxylate
- Purity
- 97%
- Packaging
- 5g
- Price
- $33.2
- Updated
- 2024/03/01
- Product number
- 546658
- Product name
- Methyl 3-amino-4-methylthiophene-2-carboxylate
- Purity
- 97%
- Packaging
- 25g
- Price
- $127
- Updated
- 2024/03/01
- Product number
- M1772
- Product name
- Methyl 3-Amino-4-methylthiophene-2-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $29
- Updated
- 2024/03/01
- Product number
- M1772
- Product name
- Methyl 3-Amino-4-methylthiophene-2-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $101
- Updated
- 2024/03/01
- Product number
- A10115
- Product name
- Methyl 3-amino-4-methylthiophene-2-carboxylate, 98%
- Packaging
- 5g
- Price
- $59.2
- Updated
- 2021/12/16
Methyl 3-amino-4-methylthiophene-2-carboxylate Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.
Application
methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.
Definition
ChEBI: Methyl 3-amino-4-methylthiophene-2-carboxylate is a thiophenecarboxylic acid.
Methyl 3-amino-4-methylthiophene-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 3-amino-4-methylthiophene-2-carboxylate Suppliers
- Tel
- --
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- Country
- Belgium
- ProdList
- 6293
- Advantage
- 73
View Lastest Price from Methyl 3-amino-4-methylthiophene-2-carboxylate manufacturers
- Product
- Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-04-22
- Product
- Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min HPLC
- Supply Ability
- 1000kgs
- Release date
- 2021-07-16
- Product
- Methyl 3-amino-4-methylthiophene-2-carboxylate 85006-31-1
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-16