2,2-DIMETHYL-BUT-3-YNOIC ACID
- Product Name
- 2,2-DIMETHYL-BUT-3-YNOIC ACID
- CAS No.
- 56663-76-4
- Chemical Name
- 2,2-DIMETHYL-BUT-3-YNOIC ACID
- Synonyms
- AKOS 91882;2,2-Dimethyl-3-butynoic acid;2,2-DIMETHYL-BUT-3-YNOIC ACID;3-Butynoic acid, 2,2-diMethyl-;2,2-DiMethyl-but-3-ynoic acidI
- CBNumber
- CB0190288
- Molecular Formula
- C6H8O2
- Formula Weight
- 112.13
- MOL File
- 56663-76-4.mol
2,2-DIMETHYL-BUT-3-YNOIC ACID Property
- Boiling point:
- 188.2±23.0 °C(Predicted)
- Density
- 1.057±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.62±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- RIDADR
- 3265
- HazardClass
- 8
- PackingGroup
- Ⅱ
- HS Code
- 2916199590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D481563
- Product name
- 2,2-Dimethylbut-3-ynoicacid
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- CHM0098174
- Product name
- 2,2-DIMETHYL-BUT-3-YNOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.31
- Updated
- 2021/12/16
- Product number
- OR917188
- Product name
- 2,2-Dimethylbut-3-ynoicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $595
- Updated
- 2021/12/16
- Product number
- OR917188
- Product name
- 2,2-Dimethylbut-3-ynoicacid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $232
- Updated
- 2021/12/16
- Product number
- AS42147
- Product name
- 2,2-Dimethylbut-3-ynoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $312
- Updated
- 2021/12/16
2,2-DIMETHYL-BUT-3-YNOIC ACID Chemical Properties,Usage,Production
Synthesis
56663-75-3
56663-76-4
NaNH2 (17.8 g, 0.458 mol, solid) and DMSO (50 mL) were added to a 500 mL three-neck flask. The mixture was stirred at room temperature until no more NH3 gas was released. A solution of 3-chloro-2,2-dimethylbut-3-enoic acid (17.0 g, 114 mmol) in DMSO (50 mL) was added slowly and dropwise at 0 °C. The reaction mixture was gradually warmed to 50 °C and stirred at this temperature for 5 h, followed by continued stirring at room temperature overnight. Upon completion of the reaction, the mixture was slowly poured into a pre-cooled 20% HCl solution and extracted three times with ether. The ether extracts were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to give a mixture of the raw material and 2,2-dimethylbut-3-ynoic acid (in a ratio of about 6:1). The residue was again dissolved in ether, dried by adding anhydrous Na2SO4 and the above reaction conditions were repeated. The reaction mixture was subjected to the same treatment to give the final 2,2-dimethylbut-3-ynoic acid (12.0 g, 94% yield).
References
[1] Patent: WO2010/53471, 2010, A1. Location in patent: Page/Page column 58-60
[2] Journal of the American Chemical Society, 1997, vol. 119, # 16, p. 3802 - 3806
[3] Journal of the American Chemical Society, 1975, vol. 97, p. 4825 - 4836
[4] Patent: US2007/244159, 2007, A1. Location in patent: Page/Page column 130
[5] Patent: US2011/98311, 2011, A1
2,2-DIMETHYL-BUT-3-YNOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,2-DIMETHYL-BUT-3-YNOIC ACID manufacturers
- Product
- 2,2-DIMETHYL-BUT-3-YNOIC ACID 56663-76-4
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12