Physical and chemical properties Toxicity
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Dimethicone

Physical and chemical properties Toxicity
Product Name
Dimethicone
CAS No.
9006-65-9
Chemical Name
Dimethicone
Synonyms
SILICONE FLUID;dimeticone;POLYMETHYLSILOXANE;DIMETHICONE 350;DIMETHYL SILICONE;POLYDIMETHYLSILOXAN;Polysilane;Dimeticone CRS;VISCOSITY STANDARD;Food defoaming agent
CBNumber
CB0696472
Molecular Formula
C6H18OSi2
Formula Weight
162.37752
MOL File
9006-65-9.mol
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Dimethicone Property

Density 
1 g/mL at 20 °C
vapor pressure 
5 mm Hg ( 20 °C)
refractive index 
n20/D 1.406
Flash point:
121 °C
storage temp. 
Refrigerator
solubility 
Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.
color 
Colourless
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, organics, acids, alkalis. Corrodes many metals.
InChI
InChI=1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3
InChIKey
UQEAIHBTYFGYIE-UHFFFAOYSA-N
SMILES
O([Si](C)(C)C)[Si](C)(C)C
LogP
3.646 (est)
CAS DataBase Reference
9006-65-9
EPA Substance Registry System
Dimethicone (9006-65-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-26
WGK Germany 
3
RTECS 
TQ2690000
Hazardous Substances Data
9006-65-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D2200000
Product name
Dimeticone
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
d2200000
Price
$220
Updated
2024/03/01
TRC
Product number
D460940
Product name
Dimethicone
Packaging
1g
Price
$95
Updated
2021/12/16
TRC
Product number
D460940
Product name
Dimethicone
Packaging
100g
Price
$340
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD34801
Product name
Dimethicone - 90%
Packaging
25g
Price
$350
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD34801
Product name
Dimethicone - 90%
Packaging
50g
Price
$450
Updated
2021/12/16
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Dimethicone Chemical Properties,Usage,Production

Physical and chemical properties

Dimethyl silicone is also known as methyl silicone oil and polydimethylsiloxane liquid. It appears as colorless transparent viscous liquid, being tasteless, odorless and non-toxic. The molecular formula is CH3 [Si (cH3) 2] nSi (CH3) 3. The average molecular weight is 5000 ~ 100000. Based on the differences on the molecular weight, kinematic viscosity varies from 1.0 × 10-6 ~ 100000 × 10-6 square meters / second. Long-term use temperature range is -50 ~ 180 ℃. In isolated air or inert gas, it can be subject to long-term use at 200 ℃. Viscosity coefficient: 0.31 ~ 0.61. Surface tension: 1.59 ~ 2.15 × 10-4N / cm. Dielectric constant (23 ℃, 100Hz): 2.18 ~ 2.17. Volume resistivity (23 °C): 1.0 × 1014 to 1.0 × 1016Ωcm3. Dielectric loss tangent (23 ℃, 100Hz):0.00002~0.00004. Breakdown voltage strength: 13.7 ~ 17.7kV / mm. It is soluble in benzene, toluene, xylene and ethyl ether, partially soluble in ethanol, butanol and acetone, insoluble in cyclohexanol, methanol, paraffin oil and vegetable oil. It has excellent hydrophobic moisture resistance, good light transmission, and chemical stability. Widely used in insulation, heat, moisture-proof filler, defoamer, mold release agent, lubricant and surface treatment agent. It is produced by the reaction between octamethylcyclotetrasiloxane and hexamethyldisiloxane in the presence of concentrated sulfuric acid or tetramethylammonium hydroxide catalyst.

Toxicity

It has no obvious acute and chronic poisoning reaction to human beings and mammals, nor be mutagenic and carcinogenic. Oral, inhalation and skin contact have no obvious irritation or allergic reaction to the eyes, skin, and can’t be absorbed by the gastrointestinal tract and skin.

Chemical Properties

colourless to slightly yellow liquid

Chemical Properties

Dimethicones are clear, colorless liquids available in various viscosities. Dimethicone is a fluid mixture of fully methylated linear siloxane polymers end-blocked with trimethylsiloxy units. Methicone is a linear monomethyl polysiloxane. Dimethicone are safe as used in cosmetic formulations, vulcanization.

Uses

dimethicone is a form of silicone used to give products lubricity, slip, and good feel. It can also serve as a formulation defoamer and help reduce the feeling of greasiness that some creams leave on the skin immediately upon application. In addition, dimethicone is reported to protect the skin against moisture loss when used in larger quantities. It improves product flow and spreadability. In combination with other ingredients, dimethicone becomes a good waterproofing material for sunscreen emulsions, and helps reduce the greasiness often seen in high-SPF preparations.

Uses

A silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsiloxy units. Commonly used in skin and hair products.

Definition

ChEBI: A polydimethylsiloxane macromolecule, composed of dimethylsiloxane repeating units.

Indications

Silicone (dimethicone) ointments are excellent water-protective agents because they have an extremely low surface tension and penetrate crevices in the skin to form a plastic-like barrier. Further, they are nontoxic, inert, stable, and water repellent. As such, they are useful as barrier creams in industry or wherever constant or frequent exposure to aqueous compounds is a problem. They will not, however, protect well against solvents, oils, or dusts.

Production Methods

Dimethicone isapoly (dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. The hydrolysis products contain active silanol groups through which condensation polymerization proceeds. By varying the proportions of chlorotrimethylsilane, which acts as a chain terminator, silicones of varying molecular weight may be prepared. Different grades of dimethicone are produced that may be distinguished by a number placed after the name indicating the nominal viscosity. For example, ABIL 20 (Evonik Goldschmidt UK Ltd) has a nominal kinematic viscosity of 18–22mm2/s (18–22cSt).

brand name

Sentry Dimethicone (Witco); Sentry Dimethicone Dispension (Witco).

Pharmaceutical Applications

Dimethicones of various viscosities are widely used in cosmetic and pharmaceutical formulations. In topical oil-in-water emulsions dimethicone is added to the oil phase as an antifoaming agent. Dimethicone is hydrophobic and is also widely used in topical barrier preparations. Therapeutically, dimethicone may be used with simethicone in oral pharmaceutical formulations used in the treatment of flatulence. Dimethicone is also used to form a waterrepellent film on glass containers.

Safety

Dimethicone is generally regarded as a relatively nontoxic and nonirritant material although it can cause temporary irritation to the eyes. In pharmaceutical formulations it may be used in oral and topical preparations. Dimethicones are also used extensively in cosmetic formulations and in certain food applications.
The WHO has set a tentative estimated acceptable daily intake of dimethicone with a relative molecular mass in the range of 200–300 at up to 1.5mg/kg body-weight.
Injection of silicones into tissues may cause granulomatous reactions. Accidental intravascular injection has been associated with fatalities.

storage

Dimethicones should be stored in an airtight container in a cool, dry, place; they are stable to heat and are resistant to most chemical substances although they are affected by strong acids. Thin films of dimethicone may be sterilized by dry heat for at least 2 hours at 160°C. Sterilization of large quantities of dimethicone by steam autoclaving is notrecommended since excesswater diffuses intothe fluid causing it to become hazy. However, thin films may be sterilized by this method. Gamma irradiation may also be used to sterilize dimethicone. Gamma irradiation can, however, cause crosslinking with a consequent increase in the viscosity of fluids.

Regulatory Status

Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules and tablets, topical creams,emulsions,lotions,and transdermal preparations).Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

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Dimethicone Suppliers

-Shanghai Chuyijia Organic Silicon Material Co., Ltd.
Tel
021-59953777 13764205959
Fax
021-59953777
Email
13764205959@163.com
Country
China
ProdList
1
Advantage
58
Jinan Hongli Chemical Industry Co. , Ltd.
Tel
18354135979
Email
970731907@qq.com
Country
China
ProdList
87
Advantage
58
Shanghai zhiping biology science and technology co., ltd
Tel
13621780388
Email
494972302@qq.com
Country
China
ProdList
45
Advantage
58
Jinan Jinbang Chemical Co., Ltd
Tel
13127153349
Email
1693669779@qq.com
Country
China
ProdList
294
Advantage
58
Shanghai shengyue international trading co., ltd
Tel
021-66690837 13166269258
Email
2570384992@qq.com
Country
China
ProdList
46
Advantage
58
Jinan Longcheng Silicone Co., Ltd
Tel
0531-88779682 13655318696
Email
2627877452@qq.com
Country
China
ProdList
58
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8844
Advantage
52
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View Lastest Price from Dimethicone manufacturers

Watson Biotechnology Co.,Ltd
Product
Dimethicone 9006-65-9
Price
US $65.00-50.00/kg
Min. Order
5kg
Purity
0.99
Supply Ability
20MT
Release date
2024-07-18
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Dimethicone 9006-65-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-23
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Dimethicone 9006-65-9
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000Ton
Release date
2024-08-13

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