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TERT-BUTYL ISOCYANIDE

Product Name
TERT-BUTYL ISOCYANIDE
CAS No.
7188-38-7
Chemical Name
TERT-BUTYL ISOCYANIDE
Synonyms
2-ISOCYANO-2-METHYL-PROPANE;TBIN;Propane, 2-isocyano-2-methyl-;T-BUTYLISOCYANIDE;TERT-BUTYL ISONITRILE;2-methylpropyl isocyanide;(CH3)3CNC;TERT-BUTYL ISOCYANIDE;2-methylpropyl cyanide;t-Butylisocyanide,min.98%
CBNumber
CB8121846
Molecular Formula
C5H9N
Formula Weight
83.13
MOL File
7188-38-7.mol
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TERT-BUTYL ISOCYANIDE Property

Melting point:
148-150 °C
Boiling point:
91 °C(lit.)
Density 
0.735 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.376(lit.)
Flash point:
-2 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in organic solvents such as ethanol, methanol, ether, toluene and dichloromethane.
form 
liquid
Specific Gravity
0.735
color 
colorless
BRN 
1903156
Exposure limits
NIOSH: IDLH 25 mg/m3
Stability:
store cold
CAS DataBase Reference
7188-38-7(CAS DataBase Reference)
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23-2017/11/23
Safety Statements 
16-45
RIDADR 
UN 1993 3/PG 2
WGK Germany 
3
RTECS 
EQ7102500
HazardClass 
3
PackingGroup 
II
HS Code 
29299090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H330Fatal if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
260630
Product name
tert-Butyl isocyanide
Purity
98%
Packaging
1g
Price
$56.6
Updated
2024/03/01
Sigma-Aldrich
Product number
260630
Product name
tert-Butyl isocyanide
Purity
98%
Packaging
5g
Price
$173
Updated
2024/03/01
TCI Chemical
Product number
B1274
Product name
tert-Butyl Isocyanide
Purity
>95.0%(GC)
Packaging
5mL
Price
$138
Updated
2024/03/01
TCI Chemical
Product number
B1274
Product name
tert-Butyl Isocyanide
Purity
>95.0%(GC)
Packaging
25mL
Price
$476
Updated
2024/03/01
Alfa Aesar
Product number
L19747
Product name
tert-Butyl isocyanide
Purity
98%
Packaging
1g
Price
$52.1
Updated
2024/03/01
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TERT-BUTYL ISOCYANIDE Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

tert-Butyl isocyanide is used in a tin-free procedure for alkyl radical reactions in the presence of a free-radical initiator. It is a useful intermediate in multicomponent reactions. It is also used in the synthesis of coumarines, 4H-chromenes, isoxazolines and to trap 2-cyclopropylidene-1,3-diones.

Preparation

Phosgene (1.0 kg, 10.1 mol) was delivered through a wide tube into a stirred solution of N-t-butylformamide (1.01 kg, 10.0 mol) in triethylamine (1.30 kg) and o-dichlorobenzene (7.0 L) in a flask fitted with a reflux condenser charged with a freezing mixture of ice and salt (-20 C°). Water was added, the layers were separated, and the non-aqueous layer was dried over anhydrous potassium carbonate or magnesium sulfate and fractionated; bp 90–92 C°/750 mmHg; yield: 681 g (82%).

Preparation

CAUTION: Use a well-ventilated hood and observe all precautions when using hydrogen cyanide.
To a 1-1, stainless steel Hoke pressure cylinder in a well-ventilated hood is added 196 gm (3.5 moles) of isobutene, 95 gm (3.5 moles) of hydrogen cyanide, and 100 gm (0.7 mole) or cuprous bromide. The cylinder is closed, shaken for 15 hr at 70°C, cooled to room temperature, and vented cautiously in the hood, and the viscous residue is poured slowly into aqueous potassium cyanide (260 gm in 100 ml of water) to decompose the cuprous complex, liberating an organic layer. The organic layer is separated, dried, and distilled under reduced pressure to afford 97 gm, b.p. 60-63°C (314 mm Hg), ng 1.3749, IR 2143 s, 1472 m, 1368 m, 1230 m, 1208 m, 855 w c m - 1; yield, 33% based on starting isobutylene; 16% based on CuBr.

General Description

Carbon dative bond formation by tert-butyl isocyanide on the germanium (100) surface has been reported. It also forms complexes with metals and inserts into metal-carbon bonds to form iminoacyls.

TERT-BUTYL ISOCYANIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL ISOCYANIDE Suppliers

Zhengzhou Kingsfine Chemical Co., Ltd.
Tel
0371-56632527 13838252817
Fax
0371-56635027
Email
sales@kingsfine.com
Country
China
ProdList
100
Advantage
62
Jinan Kabotang Biological Technology Co.,Ltd.
Tel
0531-61320525 15866703830
Email
495745175@qq.com
Country
China
ProdList
7999
Advantage
58
Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.
Tel
18602559219
Email
sales@zhiyanchem.com
Country
China
ProdList
108
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
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View Lastest Price from TERT-BUTYL ISOCYANIDE manufacturers

Henan Fengda Chemical Co., Ltd
Product
TERT-BUTYL ISOCYANIDE 7188-38-7
Price
US $6.00-0.20/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
TERT-BUTYL ISOCYANIDE 7188-38-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
TERT-BUTYL ISOCYANIDE 7188-38-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

7188-38-7, TERT-BUTYL ISOCYANIDERelated Search:


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  • TERT-BUTYL ISOCYANIDE
  • TERT-BUTYL ISONITRILE
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  • 2-isocyano-2-methyl-propan
  • 2-Methyl-2-isocyanopropane
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  • Propane,2-isocyano-2-methyl-
  • TBIN
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