Isothiazolinones
Description Applications Safety Information- Product Name
- Isothiazolinones
- CAS No.
- 26172-55-4
- Chemical Name
- Isothiazolinones
- Synonyms
- CMIT;Isothiazolinone;CMI;CMIT/MIT;5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE;MCI;5-Chloro-2-methyl-3(2H)-isothiazolone;Chloromethylisothiazolinone;5-chloro-2-methyl-2H-isothiazol-3-one;isothiazolin
- CBNumber
- CB4132565
- Molecular Formula
- C4H4ClNOS
- Formula Weight
- 149.6
- MOL File
- 26172-55-4.mol
Isothiazolinones Property
- Melting point:
- 42-45?C
- Boiling point:
- 109.7°C
- Density
- 1.25 (14% aq.)
- refractive index
- n20/D 1.378
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- -4.06±0.40(Predicted)
- form
- Liquid
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C4H4ClNOS/c1-6-4(7)2-3(5)8-6/h2H,1H3
- InChIKey
- DHNRXBZYEKSXIM-UHFFFAOYSA-N
- SMILES
- S1C(Cl)=CC(=O)N1C
- LogP
- 0.240 (est)
- CAS DataBase Reference
- 26172-55-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
- EPA Substance Registry System
- 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)
Safety
- Hazard Codes
- C,N,T,Xn
- Risk Statements
- 34-43-50-20/21/22-50/53-23/24/25-42/43
- Safety Statements
- 26-36/37/39-45-60-61-24-28-36/37-23
- RIDADR
- UN 1760 8/PG 2
- WGK Germany
- 1
- RTECS
- NX8156850
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 3808929090
- Hazardous Substances Data
- 26172-55-4(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHR1597
- Product name
- CMIT/MIT
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 1ml
- Price
- $97.5
- Updated
- 2024/03/01
- Product number
- C369235
- Product name
- 5-Chloro-2-methyl-3-isothiazolone
- Packaging
- 2.5mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- C5029-26
- Product name
- 5-Chloro-2-
- Packaging
- 2.5mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- 435989
- Product name
- 5-Chloro-2-
- Packaging
- 1mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- 161851
- Product name
- 5-Chloro-2-
- Packaging
- 1g
- Price
- $418
- Updated
- 2021/12/16
Isothiazolinones Chemical Properties,Usage,Production
Description
Isothiazolinone is a heterocyclic chemical compound related to isothiazole. Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae. Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.
Applications
Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials. Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions. Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
Safety Information
The recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful. However, allergy to skin is one of the most reported issue with isothiazolinone.
Description
Methy1chloro-isothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI. It is irritant and sensitizer.
Chemical Properties
Liquid
Uses
Isocil(R) MW-14 is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions. Suggested applications: preservative concentrate. Very low level.
Uses
Isocil(R) PC is a cost-effective antimicrobial for personal care formulations. Suggested applications: personal care preservative.
Uses
Isocil(R) RW is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems. Suggested applications: Industrial water treatment. Very low use levels.
Uses
A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.
Definition
ChEBI: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.
Isothiazolinones Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Isothiazolinones manufacturers
- Product
- Isothiazolinone 26172-55-4
- Price
- US $99.00-35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-14
- Product
- Isothiazolinones 26172-55-4
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-06-03
- Product
- Isothiazolinones 26172-55-4
- Price
- US $100.00-75.00/ton
- Min. Order
- 1ton
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-23