ChemicalBook > CAS DataBase List > Isopropyl isocyanate

Isopropyl isocyanate

Product Name
Isopropyl isocyanate
CAS No.
1795-48-8
Chemical Name
Isopropyl isocyanate
Synonyms
2-Isocyanatopropane;i-pic;Isopropylisocyanat;2-PROPYLISOCYANATE;2-isocyanato-propan;Isorpopyl Isocyanate;ISOPROPYL ISOCYANATE;Propane,2-isocyanato-;IsopropylIsocyanate>ISORPOPYL ISOCYANATE 99%
CBNumber
CB1249969
Molecular Formula
C4H7NO
Formula Weight
85.1
MOL File
1795-48-8.mol
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Isopropyl isocyanate Property

Melting point:
<-75℃
Boiling point:
74-75 °C(lit.)
Density 
0.866 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.382(lit.)
Flash point:
27 °F
storage temp. 
2-8°C
solubility 
Chloroform (Soluble), Ethyl Acetate
form 
Oil
color 
Colourless
Water Solubility 
Insoluble
Sensitive 
Moisture Sensitive
BRN 
969356
Stability:
Hygroscopic, Light Sensitive, Moisture Sensitive, Volatile
CAS DataBase Reference
1795-48-8(CAS DataBase Reference)
EPA Substance Registry System
Propane, 2-isocyanato- (1795-48-8)
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Safety

Hazard Codes 
F,T+,Xi
Risk Statements 
11-26-36/37/38-42
Safety Statements 
16-23-26-36/37/39-45
RIDADR 
UN 2483 3/PG 1
WGK Germany 
1
10-21
TSCA 
Y
HazardClass 
3
PackingGroup 
I
HS Code 
29291090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H330Fatal if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
141070
Product name
Isopropyl isocyanate
Purity
≥98%
Packaging
1g
Price
$65.5
Updated
2024/03/01
Sigma-Aldrich
Product number
141070
Product name
Isopropyl isocyanate
Purity
≥98%
Packaging
25g
Price
$242
Updated
2024/03/01
Alfa Aesar
Product number
L16105
Product name
Isopropyl isocyanate, 98+%
Packaging
1g
Price
$45
Updated
2024/03/01
TRC
Product number
I872050
Product name
Isopropyl isocyanate
Packaging
5g
Price
$195
Updated
2021/12/16
Usbiological
Product number
280261
Product name
Isopropyl isocyanate
Packaging
1g
Price
$375
Updated
2021/12/16
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Isopropyl isocyanate Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mTORC2). Further, it serves as a reagent in the synthesis of O-aryl N-isopropylcarbamates. In addition to this, it is used as a derivatization reagent during the stereoisomeric analysis of secondary alcohols.

General Description

A colorless liquid with a pungent odor. Insoluble in water. Flash point near 60°F. Very toxic by ingestion and inhalation. Vapors are heavier than air. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Isocyanates and thioisocyanates, such as Isopropyl isocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Isopropyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

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Isopropyl isocyanate Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9555
Advantage
66
Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
Country
China
ProdList
233
Advantage
65
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
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View Lastest Price from Isopropyl isocyanate manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Isopropyl isocyanate 1795-48-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
Isopropyl isocyanate 1795-48-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-11-15
Molokomalapatrading Ltd.
Product
Isopropyl isocyanate 1795-48-8
Price
US $200.00/TON
Min. Order
100TON
Purity
99%
Supply Ability
600
Release date
2022-10-14

1795-48-8, Isopropyl isocyanateRelated Search:


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