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Isocyanatocyclohexane

Product Name
Isocyanatocyclohexane
CAS No.
3173-53-3
Chemical Name
Isocyanatocyclohexane
Synonyms
cyclohexyl;CYCLOHEXYL ISOCYANATE;chi;Cyclohexane, isocyanato-;nsc87419;NSC 87419;Cyclohexylisoc;Isocyanic Acid CycL;Glipizide Impurity 5;isocyanato-cyclohexan
CBNumber
CB8399629
Molecular Formula
C7H11NO
Formula Weight
125.17
MOL File
3173-53-3.mol
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Isocyanatocyclohexane Property

Melting point:
-80 °C
Boiling point:
168-170 °C(lit.)
Density 
0.98 g/mL at 25 °C(lit.)
vapor pressure 
1.83 psi ( 20 °C)
refractive index 
n20/D 1.455(lit.)
Flash point:
120 °F
storage temp. 
Flammables area
solubility 
Chloroform (Sparingly)
form 
Liquid
color 
Clear colorless to light amber
Odor
sharp pungent odor
Water Solubility 
decomposes
Sensitive 
Moisture Sensitive
BRN 
507983
Exposure limits
ACGIH: TWA 25 ppm; STEL 50 ppm
OSHA: Ceiling 50 ppm(300 mg/m3)
NIOSH: IDLH 200 ppm; Ceiling 50 ppm(300 mg/m3)
Stability:
Stability Flammable. Incompatible with water, strong oxidizing agents, alcohols, strong bases, amines, acids, copper alloys, aluminium. May polymerize if exposed to moisture.
CAS DataBase Reference
3173-53-3(CAS DataBase Reference)
NIST Chemistry Reference
Cyclohexylisocyanate(3173-53-3)
EPA Substance Registry System
Cyclohexyl isocyanate (3173-53-3)
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Safety

Hazard Codes 
T+,N
Risk Statements 
10-21/22-26-36/37/38-42-50-34
Safety Statements 
26-28-36/37-45-57-36/37/39-29-28A-23-16
RIDADR 
UN 2488 6.1/PG 1
WGK Germany 
2
RTECS 
NQ8650000
10-19-21
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
I
HS Code 
29291090
Hazardous Substances Data
3173-53-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H330Fatal if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C105198
Product name
Cyclohexyl isocyanate
Purity
98%
Packaging
25g
Price
$35.5
Updated
2024/03/01
Sigma-Aldrich
Product number
C105198
Product name
Cyclohexyl isocyanate
Purity
98%
Packaging
100g
Price
$45.3
Updated
2024/03/01
Sigma-Aldrich
Product number
C105198
Product name
Cyclohexyl isocyanate
Purity
98%
Packaging
500g
Price
$39
Updated
2024/03/01
Usbiological
Product number
267340
Product name
Cyclohexyl isocyanate
Packaging
500g
Price
$240
Updated
2021/12/16
TRC
Product number
C986305
Product name
Cyclohexyl isocyanate
Packaging
50g
Price
$85
Updated
2021/12/16
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Isocyanatocyclohexane Chemical Properties,Usage,Production

Description

Cyclohexyl isocyanate is a clear, flammableliquid. It has a sharp, pungent odor. Molecularweight=125.19; Specific gravity (H2O:1): 0.98; Boilingpoint=168℃; Flash point=48℃ (cc). HazardIdentification (based on NFPA-704 M Rating System):Health 2, Flammability 2, Reactivity 0. Soluble in water(reaction).

Chemical Properties

colourless or light yellow liquid

Chemical Properties

Cyclohexyl isocyanate is a clear, flammable liquid. It has a sharp, pungent odor.

Uses

Cyclohexyl Isocyanate reacts with isoquinoline to prepare of Gliquidone through condensation reaction in a solvent under the action of base.

Definition

ChEBI: An isocyanate comprising a cyclohexane core with a single isocyanato substituent.

General Description

A yellowish liquid with an irritating odor. Insoluble in water. Flash point 127°F. Very toxic by inhalation, skin absorption and ingestion. Used to make pharmaceuticals and agricultural chemicals.

Air & Water Reactions

Flammable. Insoluble in water. Reacts slowly with water to form the amine and CO2.

Reactivity Profile

Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Poison by intravenous and intraperitoneal routes. Mutation data reported. A flammable liquid when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NOx. See also CYANATES and ESTERS.

Potential Exposure

The material is used in the synthesis of agricultural chemicals.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least30 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24-48 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a corticosteroid spray.

storage

Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Color Code—Blue: Health Hazard/Poison: Store in a securepoison location. Prior to working with cyclohexyl isocyanate you should be trained on its proper handling and storage. Cyclohexyl isocyanate must be stored to avoid contactwith moisture and temperatures above 93℃, since violentreactions occur. Store in tightly closed containers in a cool,well-ventilated area away from water, strong bases, alcohol,metal compounds, or surface-active materials. Use onlynonsparking tools and equipment, especially when openingand closing containers of this chemical. Sources of ignition,such as smoking and open flames, are prohibited where thischemical is used, handled, or stored in a manner that couldcreate a potential fire or explosion hazard

Shipping

UN2488 Cyclohexyl isocyanate, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Inhalation Hazard Zone B.

Incompatibilities

Cyclohexyl isocyanate polymerize due toheating above 93℃/200°F and under the influence of various chemicals including organometallic compounds.Cyclohexyl isocyanate decomposes in fire, forming toxichydrogen cyanide and nitrogen oxides fumes. Reacts withoxidizers, strong bases, water, alcohol, acids, amines, metalcompounds, surface-active materials

Isocyanatocyclohexane Preparation Products And Raw materials

Raw materials

Preparation Products

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Isocyanatocyclohexane Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9414
Advantage
66
Xian rui kang pharmaceutical technology Co., LTD.
Tel
(0)18629586220 +86-029-88499520
Fax
+86-029-85861203
Email
yws0123@hotmail.com
Country
China
ProdList
28
Advantage
59
Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
Country
China
ProdList
233
Advantage
65
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Isocyanatocyclohexane manufacturers

Qingdao RENAS Polymer Material Co., Ltd.
Product
Cyclohexyl isocyanate 3173-53-3
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-08-18
Hefei TNJ Chemical Industry Co.,Ltd.
Product
Cyclohexyl Isocyanate 3173-53-3
Price
US $0.00/L
Min. Order
200L
Purity
99%
Supply Ability
1000MT
Release date
2019-03-08
Career Henan Chemical Co
Product
Isocyanatocyclohexane 3173-53-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-15

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