4-(4-Pyridinyl)benzaldehyde

Product Name: 4-(4-Pyridinyl)benzaldehyde
CAS No.: 99163-12-9
Chemical Name: 4-(4-Pyridinyl)benzaldehyde
Synonyms: AKOS BAR-0607;4-(4-PYRIDYL)BENZALDEHYDE;4-(4-FORMYLPHENYL)PYRIDINE;4-(4-PYRIDINYL)BENZALDEHYDE;4-PYRIDIN-4-YL-BENZALDEHYDE;4-(4-Pyridyl)benzaldehyde>Benzaldehyde, 4-(4-pyridinyl)-;4-PYRIDIN-4-YL-BENZALDEHYDE, 95+%;4-(3-Fluoropyridin-4-yl)benzaldehyde;4-(2-Fluoropyridin-4-yl)benzaldehyde
CBNumber: CB0208594
Molecular Formula: C12H9NO
Formula Weight: 183.21
MOL File: 99163-12-9.mol

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4-(4-Pyridinyl)benzaldehyde Property

Melting point:: 85-89 °C (lit.)
Boiling point:: 336.7±25.0 °C(Predicted)
Density: 1.147±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 4.98±0.10(Predicted)
color: White to Orange to Green
InChI: InChI=1S/C12H9NO/c14-9-10-1-3-11(4-2-10)12-5-7-13-8-6-12/h1-9H
InChIKey: MBJXDIYHLGBQOT-UHFFFAOYSA-N
SMILES: C(=O)C1=CC=C(C2C=CN=CC=2)C=C1
CAS DataBase Reference: 99163-12-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36/37/39-22
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 645982
Product name: 4-(4-Formylphenyl)pyridine
Purity: 97%
Packaging: 1g
Price: $102
Updated: 2023/06/20

Sigma-Aldrich

Product number: 645982
Product name: 4-(4-Formylphenyl)pyridine
Purity: 97%
Packaging: 5g
Price: $451
Updated: 2023/06/20

TCI Chemical

Product number: P1983
Product name: 4-(4-Pyridyl)benzaldehyde
Purity: >98.0%(GC)
Packaging: 200mg
Price: $137
Updated: 2024/03/01

TCI Chemical

Product number: P1983
Product name: 4-(4-Pyridyl)benzaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $482
Updated: 2024/03/01

TRC

Product number: P996968
Product name: 4-Pyridin-4-yl-benzaldehyde
Packaging: 100mg
Price: $75
Updated: 2021/12/16

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4-(4-Pyridinyl)benzaldehyde Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

1692-15-5

1122-91-4

99163-12-9

Pyridine-4-boronic acid (498.3 mg, 4.05 mmol) and p-bromobenzaldehyde (500 mg, 2.70 mmol) were added to bis(triphenylporphyrinophosphate) palladium dichloride Pd(PPh3)2Cl2 (94.65 mg, 0.14 mmol) as a catalyst and dissolved in 20 mL of a solvent mixture of tetrahydrofuran and toluene (Vtoluene: VTHF = 1:1) in it. The reaction mixture was heated to 90°C under nitrogen protection for reflux reaction and the reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction solution was concentrated to remove the organic solvent and subsequently extracted with ethyl acetate. The organic layer was washed sequentially with water three times, saturated sodium chloride solution once, and then dried with anhydrous sodium sulfate. The dried organic phase was evaporated under reduced pressure to remove the solvent to obtain the crude product. The crude product was purified by silica gel column chromatography using a mixed solvent of petroleum ether and ethyl acetate (20:1) as eluent to finally obtain 4-(pyridin-4-yl)benzaldehyde (white solid, 288.7 mg, 68.4% yield).

References

[1] Journal of the American Chemical Society, 2018, vol. 140, # 21, p. 6622 - 6630
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 18, p. 8402 - 8416
[3] Crystal Growth and Design, 2018, vol. 18, # 11, p. 6936 - 6945
[4] Patent: CN105418515, 2016, A. Location in patent: Paragraph 0087; 0088; 0089
[5] Angewandte Chemie - International Edition, 2006, vol. 45, # 17, p. 2761 - 2766

4-(4-Pyridinyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Pyridinyl)benzaldehyde Suppliers

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View Lastest Price from 4-(4-Pyridinyl)benzaldehyde manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-(4-Pyridinyl)benzaldehyde 99163-12-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-(4-Pyridyl)benzaldehyde 99163-12-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 4-(4-Pyridinyl)benzaldehyde 99163-12-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-07

99163-12-9, 4-(4-Pyridinyl)benzaldehydeRelated Search:

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AKOS BAR-0607

4-PYRIDIN-4-YL-BENZALDEHYDE

4-(4-PYRIDINYL)BENZALDEHYDE

4-(4-PYRIDYL)BENZALDEHYDE

4-(4-FORMYLPHENYL)PYRIDINE

4-(2-Chloropyridin-4-yl)benzaldehyde

4-(2-Fluoropyridin-4-yl)benzaldehyde

4-(3-Fluoropyridin-4-yl)benzaldehyde

4-PYRIDIN-4-YL-BENZALDEHYDE, 95+%

4-(4-Pyridyl)benzaldehyde&gt

Benzaldehyde, 4-(4-pyridinyl)-

99163-12-9