4-(2-Pyridinyl)benzaldehyde

Product Name: 4-(2-Pyridinyl)benzaldehyde
CAS No.: 127406-56-8
Chemical Name: 4-(2-Pyridinyl)benzaldehyde
Synonyms: 4-(PYRIDIN-2-YL)BENZALDEHYDE;4-(2-PYRIDYL)BENZALDEHYDE;AKOS BAR-0490;4-Pyridylenzaldehyde;Atazanavir Impurity 12;Pyridinyl Benzaldehyde;Azanavir EP Impurity B;Atazanavir EP Impurity B;-(2-Pyridyl)benzaldehyde;Atazanavir EP Impurity 6
CBNumber: CB6351081
Molecular Formula: C12H9NO
Formula Weight: 183.21
MOL File: 127406-56-8.mol

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4-(2-Pyridinyl)benzaldehyde Property

Melting point:: 50-52 °C(lit.)
Boiling point:: 340.4±25.0 °C(Predicted)
Density: 1.147±0.06 g/cm3(Predicted)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in Chloroform
pka: 3.97±0.25(Predicted)
form: Solid
color: White to Off-White Waxy
CAS DataBase Reference: 127406-56-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37-36/37/39-22
WGK Germany: 3
Hazard Note: Harmful
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 489387
Product name: 4-(2-Pyridyl)benzaldehyde
Purity: 97%
Packaging: 5g
Price: $73.6
Updated: 2023/06/20

Sigma-Aldrich

Product number: 572411
Product name: 4-(2-Pyridyl)benzaldehyde
Purity: 99%
Packaging: 5g
Price: $51.5
Updated: 2022/05/15

TCI Chemical

Product number: P1671
Product name: 4-(2-Pyridyl)benzaldehyde
Purity: >95.0%(GC)(T)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: P1671
Product name: 4-(2-Pyridyl)benzaldehyde
Purity: >95.0%(GC)(T)
Packaging: 5g
Price: $63
Updated: 2025/07/31

TRC

Product number: P992125
Product name: 4-(2-Pyridinyl)benzaldehyde
Packaging: 10g
Price: $235
Updated: 2021/12/16

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4-(2-Pyridinyl)benzaldehyde Chemical Properties,Usage,Production

Chemical Properties

White Waxy Solid

Uses

Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity

General Description

4-(2-Pyridyl)benzaldehyde is a p-substituted benzaldehyde.

Synthesis

109-04-6

87199-17-5

127406-56-8

General procedure for the synthesis of 4-(2-pyridyl)-benzaldehyde from 2-bromopyridine and 4-formylphenylboronic acid: 1.1 equiv. of the brominated derivatives (13- of 2-bromopyridine and 14- of 1-bromo-4-nitrobenzene) of 4-formylphenylboronic acid, Pd(OAc)2 (2 mol%), and PPh3 (4 mol%) were added to a Schlenk flask. Methanol/THF (1:1, 2 mL/mmol) and 2 eq. of KOH were added under an inert atmosphere. the reaction system was stirred at 60 °C for 24 h. The reaction system was then purified by column chromatography. The target compounds were purified by column chromatography (eluent: cyclohexane/EtOAc, 9:1) to afford the products 13a and 14a in 80% and 75% yields, respectively.

References

[1] European Journal of Organic Chemistry, 2008, # 12, p. 2049 - 2055
[2] Angewandte Chemie - International Edition, 2015, vol. 54, # 47, p. 14103 - 14107
[3] Angew. Chem., 2015, vol. 127, # 47, p. 14309 - 14313,5
[4] Organic and Biomolecular Chemistry, 2013, vol. 11, # 39, p. 6806 - 6813
[5] European Journal of Organic Chemistry, 2014, vol. 2014, # 27, p. 5901 - 5905

4-(2-Pyridinyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-Pyridinyl)benzaldehyde Suppliers

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View Lastest Price from 4-(2-Pyridinyl)benzaldehyde manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4-(2-Pyridinyl)benzaldehyde 127406-56-8
Price: US $0.23/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 3000ton
Release date: 2021-11-23

Dideu Industries Group Limited

Product: 4-(2-Pyridinyl)benzaldehyde 127406-56-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-25

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-(2-Pyridinyl)benzaldehyde 127406-56-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

127406-56-8, 4-(2-Pyridinyl)benzaldehydeRelated Search:

Benzaldehyde 2-Nitrobenzaldehyde 2-Pyridinecarboxaldehyde 4-Hydroxybenzaldehyde 4-Dimethylaminobenzaldehyde H-GAMMA-GLU-GLU-OH Nalpha-Cbz-L-Arginine DIANTIPYRYLMETHANE LDAO 1-Pyrrolidino-1-cyclopentene N-EPSILON-ACETYL-L-LYSINE N-ALPHA-BENZOYL-L-ARGININE 1-Methyl-2-pyrrolidineethanol OIL BLUE N N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) 2-(2-Aminoethyl)-1-methylpyrrolidine 4-(2-Pyridyl)benzoic acid N6-Cbz-L-Lysine

Atazanavir EP Impurity B

Pyridinyl Benzaldehyde

Atazanavir Impurity 12

Atazanavir Impurity 16 (Pyridinyl Benzaldehyde)

Benzaldehyde, 4-(2-pyridinyl)-

4-(2-Pyridiyl)benzaldehyde

4-(2-pyridinyl)phenylaldyhyde

(4-(pyridine-2-yl)benzaldehyde

4-PYRIDIN-2-YL-BENZALDEHYDE, 95+%

4-Pyridylenzaldehyde

4-(2-Pyridyl)benzaldehyde,97%

2-(p-ForMylphenyl)pyridine

4-(pyridin-2-yl)-benzaldehyde, 2-(4-forMyl-phenyl)pyridine, 4-(pyrid-2-yl)-benzaldehyde, 4-α-pyridylbenzaldehyde, 4-(pyridin-2-yl)benzaldehyde, 2-(4-forMylphenyl)pyridine, 4-(2'-pyridyl)benzaldehyde

Atazanavir iMpurity (Pyridinyl benzaldehyde)

4-(2-Pyridyl)benzaldehyde 97%

2-(4-FORMYLPHENYL)PYRIDINE

4-(PYRIDIN-2-YL)BENZALDEHYDE

4-(2-PYRIDYL)BENZALDEHYDE

4-(2-PYRIDINYL)BENZALDEHYDE

AKOS BAR-0490

4-(2-Pyridyl)benzaldehyde&gt

4-(2-Pyridinyl)benzaldehyde ISO 9001：2015 REACH

Atazanavir Related Compund E

-(2-Pyridyl)benzaldehyde

Atazanavir Sulfate EP Impurity B

Azanavir EP Impurity B

Atazanavir Sulfate Impurity B

4-(2'-Pyridyl)Benzaldehyde

Atazanavir EP Impurity 6

127406-56-8

12406-56-8

27406-56-8

Heterocyclic Building Blocks

Pyridines

Building Blocks

C9 to C46

pharmacetical

Aldehydes

Phenyls & Phenyl-Het

Pyridines

Bases & Related Reagents

Heterocycles

Nucleotides

Phenyls & Phenyl-Het

C9 to C46

Heterocyclic Building Blocks

Pyridine