4-(2-Pyridyl)benzoic acid

Product Name: 4-(2-Pyridyl)benzoic acid
CAS No.: 4385-62-0
Chemical Name: 4-(2-Pyridyl)benzoic acid
Synonyms: 4-(PYRIDIN-2-YL)BENZOIC ACID;AKOS BAR-0485;RARECHEM AL BE 0861;Atazanavir impurity A;Atazanavir Impurity 11;Pyridinyl Benzoic Acid;Azanavir EP Impurity A;4-(2-pyridinyl)benzoate;Atazanavir EP Impurity A;Atazanavir EP Impurity 7
CBNumber: CB8257154
Molecular Formula: C12H9NO2
Formula Weight: 199.21
MOL File: 4385-62-0.mol

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4-(2-Pyridyl)benzoic acid Property

Melting point:: 236.0 to 240.0 °C
Boiling point:: 388.1±25.0 °C(Predicted)
Density: 1.241±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 3.17±0.10(Predicted)
color: White to Light Grey
CAS DataBase Reference: 4385-62-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P2455
Product name: 4-(2-Pyridyl)benzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $102
Updated: 2025/07/31

TCI Chemical

Product number: P2455
Product name: 4-(2-Pyridyl)benzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $353
Updated: 2025/07/31

TRC

Product number: P992140
Product name: 4-(2-Pyridinyl)benzoicAcid
Packaging: 1g
Price: $145
Updated: 2021/12/16

Matrix Scientific

Product number: 071826
Product name: 4-Pyridin-2-yl-benzoic acid
Purity: 95+%
Packaging: 1g
Price: $85
Updated: 2021/12/16

Apolloscientific

Product number: OR912706
Product name: 4-(2-Pyridyl)benzoic Acid
Purity: 98%
Packaging: 1g
Price: $110
Updated: 2021/12/16

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4-(2-Pyridyl)benzoic acid Chemical Properties,Usage,Production

Uses

Reactive metabolite of Atazanavir (A790051). Atazanavir Impurity (Pyridinyl Benzoic Acid)

Synthesis

4467-06-5

4385-62-0

Example 10: Synthesis of 4-(2-pyridyl)benzoic acid In a 100 mL jacketed reactor, 200 mL of acetic acid, 0.05 g of manganese(II) acetate, 1.74 g of sulfuric acid, and 3.0 g of 2-(4-methylphenyl)pyridine were sequentially added. The reaction mixture was cooled to 16°C, followed by slow passage of 4.0 g of ozone over 60 minutes. Upon completion of the ozonolysis reaction, the reaction was purged with nitrogen to remove residual ozone from the solvent. The reaction mixture was analyzed by HPLC or GC, which showed that the residue of 2-(4-methylphenyl)pyridine was <0.1% and the yield of 4-(2-pyridyl)benzoic acid was 94-97%.

References

[1] Patent: US2003/216577, 2003, A1. Location in patent: Page/Page column 4
[2] Dyes and Pigments, 2017, vol. 140, p. 269 - 277
[3] Dyes and Pigments, 2011, vol. 91, # 3, p. 413 - 421
[4] Journal of the Chemical Society, 1956, p. 100,101
[5] Patent: US5854264, 1998, A

4-(2-Pyridyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-Pyridyl)benzoic acid Suppliers

Canada 2 China 107 Germany 4 India 12 Japan 2 Russia 1 The Netherlands 1 United Kingdom 4 United States 21 Global 154

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View Lastest Price from 4-(2-Pyridyl)benzoic acid manufacturers

Career Henan Chemical Co

Product: 4-(2-Pyridyl)benzoic acid 4385-62-0
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-24

4385-62-0, 4-(2-Pyridyl)benzoic acidRelated Search:

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RARECHEM AL BE 0861

4-(PYRIDIN-2-YL)BENZOIC ACID

4-(2-PYRIDYL)BENZOIC ACID

4-(2-PYRIDINYL)BENZOIC ACID

AKOS BAR-0485

4-Pyridin-2-yl-benzoicacid95%

4-(3-Fluoropyridin-2-yl)benzoic acid

4-(4-Chloropyridin-2-yl)benoic acid

4-(4-Fluoropyridin-2-yl)benzoic acid

4-(5-Fluoropyridin-2-yl)benoic acid

Atazanavir iMpurity (Pyridinyl benzoic acid)

Benzoic acid, 4-(2-pyridinyl)-

Benzoic acid, p-2-pyridyl-

4-(2-pyridinyl)benzoate

Atazanavir Impurity 11

Pyridinyl Benzoic Acid

Atazanavir EP Impurity A

Atazanavir Impurity 15 (Pyridinyl Benzoic Acid)

Atazanavir impurity A

Atazanavir Related Compund D

4-(2-Pyridyl)benzoic acid?New

Azanavir EP Impurity A

Atazanavir EP Impurity 7

4385-62-0

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