Estradiol benzoate
- Product Name
- Estradiol benzoate
- CAS No.
- 50-50-0
- Chemical Name
- Estradiol benzoate
- Synonyms
- ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;diogynb;ESTON-B;Diogyn B
- CBNumber
- CB9131644
- Molecular Formula
- C25H28O3
- Formula Weight
- 376.5
- MOL File
- 50-50-0.mol
Estradiol benzoate Property
- Melting point:
- 191-198 °C(lit.)
- alpha
- D25 +58 to +63° (c = 2 in dioxane)
- Boiling point:
- 465.03°C (rough estimate)
- Density
- 1.0493 (rough estimate)
- refractive index
- 1.5460 (estimate)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
- pka
- 15.06±0.40(Predicted)
- form
- Solid
- color
- White
- Water Solubility
- 0.4mg/L(25 ºC)
- Merck
- 3703
- BRN
- 3107526
- CAS DataBase Reference
- 50-50-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Estradiol benzoate(50-50-0)
Safety
- Hazard Codes
- T
- Risk Statements
- 60-61-40
- Safety Statements
- 53-22-36/37/39-45
- WGK Germany
- 3
- RTECS
- KG4050000
- F
- 8
- HS Code
- 29372319
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E8515
- Product name
- β-Estradiol 3-benzoate
- Purity
- ≥97%
- Packaging
- 1g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- PHR2858
- Product name
- Estradiol Benzoate
- Purity
- certified reference material, pharmaceutical secondary standard
- Packaging
- 500MG
- Price
- $286
- Updated
- 2024/03/01
- Product number
- BP396
- Product name
- Estradiol benzoate
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 50MG
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 1251000
- Product name
- Estradiol benzoate
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 250mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- 10006487
- Product name
- Estradiol Benzoate
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $32
- Updated
- 2024/03/01
Estradiol benzoate Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
antiacne, antineoplastic
Uses
Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.
Definition
ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use
Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.
Estradiol benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Estradiol benzoate manufacturers
- Product
- Estradiol benzoate 50-50-0
- Price
- US $0.00/g/Bag
- Min. Order
- 100g
- Purity
- 97.0~103.0%; USP43
- Supply Ability
- 800kg/month
- Release date
- 2021-06-03
- Product
- estradiol benzoate 50-50-0
- Price
- US $0.00-0.00/Kg/Bag
- Min. Order
- 0.10000000149011612Kg/Bag
- Purity
- USP, GMP
- Supply Ability
- 2tons
- Release date
- 2024-06-27
- Product
- Estradiol benzoate 50-50-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500
- Release date
- 2023-07-31