Isopropylparaben
- Product Name
- Isopropylparaben
- CAS No.
- 4191-73-5
- Chemical Name
- Isopropylparaben
- Synonyms
- ISOPROPYL 4-HYDROXYBENZOATE;ISOPROPYL P-HYDROXYBENZOATE;ISOPROPYLPARABEN;Baquiloprim Impurity 1;ISOPROPYLHYDROXYBENZOATE;Isopropyl 4-hydroxybenzo;4-(1-Isopropoxyvinyl)phenol;Isopropyl 4-Hydroxubenzoate;ISOPROPYLPARA-HYDROXYBENZOATE;Iso proply p-hydroxybenzoate
- CBNumber
- CB6374932
- Molecular Formula
- C10H12O3
- Formula Weight
- 180.2
- MOL File
- 4191-73-5.mol
Isopropylparaben Property
- Melting point:
- 84-86°C
- Boiling point:
- 160 °C / 5mmHg
- Density
- 1.132±0.06 g/cm3(Predicted)
- vapor pressure
- 0.155Pa at 25℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in Chloroform, Ethyl Acetate.
- form
- powder to lump
- pka
- 8.40±0.15(Predicted)
- color
- White
- Water Solubility
- 1.204g/L
- BRN
- 2641564
- LogP
- 2.316 at 25℃
- CAS DataBase Reference
- 4191-73-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Isopropyl-4-hydroxybenzoate(4191-73-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H0494
- Product name
- Isopropyl 4-Hydroxybenzoate
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $18
- Updated
- 2025/07/31
- Product number
- H0494
- Product name
- Isopropyl 4-Hydroxybenzoate
- Purity
- >99.0%(T)
- Packaging
- 100g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- I0817
- Product name
- Isopropyl 4-Hydroxybenzoate [for Biochemical Research]
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $16
- Updated
- 2025/07/31
- Product number
- I0817
- Product name
- Isopropyl 4-Hydroxybenzoate [for Biochemical Research]
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $41
- Updated
- 2025/07/31
- Product number
- H0494
- Product name
- Isopropyl 4-Hydroxybenzoate
- Purity
- >99.0%(T)
- Packaging
- 500g
- Price
- $217
- Updated
- 2025/07/31
Isopropylparaben Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
It is used as a preservative in cosmetics.
Uses
An antimicrobial
Definition
ChEBI: Isopropylparaben is a 4-hydroxybenzoate ester.
Contact allergens
This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Synthesis
67-63-0
99-96-7
4191-73-5
GENERAL METHOD: Thionyl chloride (1.16 g, 1.5 eq.) was slowly added dropwise to a solution of p-hydroxybenzoic acid (1.0 g, 1.0 eq.) dissolved in isopropanol (15 ml) at 0 °C. The reaction mixture was heated to reflux under nitrogen protection until thin layer chromatography (TLC) monitoring showed complete consumption of p-hydroxybenzoic acid. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent being a solvent mixture of ethyl acetate/hexane to give the final isopropyl 4-hydroxybenzoate.
References
[1] Synthesis, 2003, # 16, p. 2479 - 2482
[2] Phosphorus, Sulfur and Silicon and the Related Elements, 2004, vol. 179, # 6, p. 1187 - 1191
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 6, p. 1564 - 1569
[4] Journal of the Society of Chemical Industry, London, 1947, vol. 66, p. 175
[5] Archiv der Pharmazie (Weinheim, Germany), 1938, vol. 276, p. 154,162
Isopropylparaben Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Isopropylparaben manufacturers
- Product
- Isopropylparaben 4191-73-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- Isopropyl 4-hydroxybenzoate 4191-73-5
- Price
- US $1.00-35.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-07-30
- Product
- Isopropylparaben 4191-73-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09