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SYROSINGOPINE

Product Name
SYROSINGOPINE
CAS No.
84-36-6
Chemical Name
SYROSINGOPINE
Synonyms
HF-41T;Ipores;su3118;Isotens;Su 3118;Raunova;arbonate;Etropres;Isotense;Londomin
CBNumber
CB5193628
Molecular Formula
C35H42N2O11
Formula Weight
666.72
MOL File
84-36-6.mol
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SYROSINGOPINE Property

Melting point:
175°C
Boiling point:
686.09°C (rough estimate)
Density 
1.2536 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
18.11±0.70(Predicted)
form 
Solid
color 
Beige
LogP
3.510 (est)
CAS DataBase Reference
84-36-6(CAS DataBase Reference)
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 oral in rat: > 2gm/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FS65931
Product name
Syrosingopine
Packaging
25mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65931
Product name
Syrosingopine
Packaging
50mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65931
Product name
Syrosingopine
Packaging
100mg
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS65931
Product name
Syrosingopine
Packaging
250mg
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004304
Product name
SYROSINGOPINE
Purity
95.00%
Packaging
10MG
Price
$782.23
Updated
2021/12/16
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SYROSINGOPINE Chemical Properties,Usage,Production

Chemical Properties

White or slightly yellowish powder. Practically insoluble in water; slightly soluble in methanol; soluble in chloroform and acetic acid.

Originator

Singoserp,Ciba,US,1958

Uses

Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.

Uses

Medicine.

Definition

Methyl reserpate ester of syringic acid ethyl carbonate. An analog of reserpine.

Manufacturing Process

1 part by weight of methyl reserpate and 1.9 parts by weight of Ocarbethoxysyringoyl chloride were dissolved in 20 parts by volume of anhydrous pyridine and allowed to stand at 5°C for 3 days. An equal volume of ice was then added, and the mixture evaporated to dryness in vacuo. The residue was dissolved in 50 parts by volume of chloroform and washed in succession with three 50 parts by volume portions of 2% sodium hydroxide solution and two 50 parts by volume portions of water. The chloroform solution was dried over sodium sulfate and evaporated to dryness. The residue was dissolved in 15 parts by volume of benzene and chromatographed on a 10 part by weight column of II-III grade alumina. Eluates of benzene, 90 benzene: 10 acetone, 80 benzene: 20 acetone, 60 benzene: 40 acetone; and acetone were removed. From the 90 benzene: 10 acetone eluate there was recovered crystalline methyl O-(O'-carbethoxysyringoyl)-reserpate, melting point 175°C to 178°C, on crystallization from acetone.

Therapeutic Function

Antihypertensive

target

HCV | Antifection | Androgen Receptor | Histone Methyltransferase | NF-kB | Mdm2

SYROSINGOPINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SYROSINGOPINE Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3404
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 15920483169
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17944
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9590
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
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View Lastest Price from SYROSINGOPINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Syrosingopine 84-36-6
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
1000 tons
Release date
2020-01-02
Career Henan Chemical Co
Product
SYROSINGOPINE 84-36-6
Price
US $8.00/KG
Min. Order
1g
Purity
>98% HPLC
Supply Ability
kg--ton
Release date
2020-02-20

84-36-6, SYROSINGOPINERelated Search:


  • SYROSINGOPINE(RG)
  • 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI)
  • NSC 77030
  • Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate (6CI)
  • Yohimban-16-carboxylic acid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3b,16b,17a,18b,20a)- (9CI)
  • Isotens
  • SYROSINGOPINE
  • 18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-yohimban-16-carboxylic acid methyl ester
  • 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester)
  • 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate
  • arbonate
  • Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ethyl carbonate, ester with methyl reserpate
  • benzoicacid,4-hydroxy-3,5-dimethoxy-,ethylcarbonate,esterwithmethylre
  • Carbethoxysyringoyl methylreserpate
  • carbethoxysyringoylmethylreserpate
  • Elufinesin
  • Etropres
  • HF-41T
  • imethoxy-,methylester,esterwith4-hydroxy-3,5-dimethoxybenzoicacidethylc
  • Ipores
  • Siringina
  • Siringone
  • Siriserpin
  • Siroshuten
  • Su 3118
  • su3118
  • Syringic acid ethyl carbonate ester with methyl reserpate
  • syringicacidethylcarbonateesterwithmethylreserpate
  • Syringopine
  • Syrosingopin
  • thylcarbonate
  • Vegaserpina
  • Yohimban-16-carboxylic acid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha
  • Reserpine Impurity 10
  • Isotense
  • Londomin
  • Menatensina
  • Methyl 18-((4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxyyohimban-16-carboxylate
  • Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 4-hydroxy
  • Methyl carbethoxysyringoyl reserpate
  • Methyl reserpate ester of syringic acid ethyl carbonate
  • Methyl reserpate, 4-ethoxycarbonyl-3,5-dimethoxybenzoic acid ester
  • methylcarbethoxysyringoylreserpate
  • methylreserpate,4-ethoxycarbonyl-3,5-dimethoxybenzoicacidester
  • methylreserpateesterofsyringicacidethylcarbonate
  • Neoreserpan
  • Nichiserpine-S
  • Novoserpina
  • Raunova
  • Reserpic acid, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate
  • reserpicacid,methylester,esterwith4-hydroxy-3,5-dimethoxybenzoicacide
  • Revelox-Wirkstoff
  • Seniramin
  • Seringina
  • Serpagon
  • Singoserp
  • Siringal
  • (1S,2R,3R,4aS,13bR,14aS)-3-(4-carbethoxyoxy-3,5-dimethoxy-benzoyl)oxy-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester