Syringic acid
- Product Name
- Syringic acid
- CAS No.
- 530-57-4
- Chemical Name
- Syringic acid
- Synonyms
- 4-HYDROXY-3,5-DIMETHOXYBENZOIC ACID;Syringate;Cedar acid;Benzoic acid, 4-hydroxy-3,5-dimethoxy-;cedaracid;Suringic acid;Syringle acid;RARECHEM AL BE 0102;SYRA;NSC 2129
- CBNumber
- CB3381988
- Molecular Formula
- C9H10O5
- Formula Weight
- 198.17
- MOL File
- 530-57-4.mol
Syringic acid Property
- Melting point:
- 205-209 °C (lit.)
- Boiling point:
- 192-193°C 14mm
- Density
- 1.2539 (rough estimate)
- refractive index
- 1.4570 (estimate)
- Flash point:
- 192-193°C/14mm
- storage temp.
- Store below +30°C.
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.33±0.10(Predicted)
- form
- Powder
- color
- Grayish-beige to light brown
- Water Solubility
- 5780 mg/L (25 ºC)
- BRN
- 2115262
- Stability:
- Stable. Incompatible with strong bases, strong oxidizing agents.
- Major Application
- cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care - Cosmetics Ingredients Functions
- ANTIOXIDANT
- InChI
- 1S/C9H10O5/c1-13-6-3-5(9(11)12)4-7(14-2)8(6)10/h3-4,10H,1-2H3,(H,11,12)
- InChIKey
- JMSVCTWVEWCHDZ-UHFFFAOYSA-N
- SMILES
- COc1cc(cc(OC)c1O)C(O)=O
- LogP
- 1.040
- CAS DataBase Reference
- 530-57-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 4-hydroxy-3,5-dimethoxy-(530-57-4)
- EPA Substance Registry System
- Syringic acid (530-57-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- DH2090000
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HS Code
- 29189090
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S6881
- Product name
- Syringic acid
- Purity
- ≥95% (HPLC)
- Packaging
- 5g
- Price
- $70.1
- Updated
- 2025/07/31
- Product number
- PHL82659
- Product name
- Syringic acid
- Purity
- phyproof<SUP>®</SUP> Reference Substance
- Packaging
- 100 mg
- Price
- $231
- Updated
- 2025/07/31
- Product number
- 8.22161
- Product name
- 4-Hydroxy-3,5-dimethoxybenzoic acid
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $55
- Updated
- 2025/07/31
- Product number
- 63627
- Product name
- Syringic acid
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $86.9
- Updated
- 2025/07/31
- Product number
- G0014
- Product name
- Syringic Acid
- Purity
- >97.0%(T)
- Packaging
- 25g
- Price
- $77
- Updated
- 2025/07/31
Syringic acid Chemical Properties,Usage,Production
Description
Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol. It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities. Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 μg/ml), proteasome activity, and cancer cell proliferation. Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.
Chemical Properties
light brown powder
Uses
antiproliferative; antifungal
Uses
Syringic Acid is used in biological studies for electron transfer from plant phenolates to carotenoid radical cations with antioxidant interaction entering the Marcus theory inverted region.
Definition
ChEBI: A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.
Purification Methods
Recrystallise syringic acid from H2O using charcoal [Bogert & Coyne J Am Chem Soc 51 571 1929, Anderson & Nabenhauer J Am Chem Soc 48 3001 1926.] The methyl ester has m 107o (from MeOH), the 4-acetyl derivative has m 190o and the 4-benzoyl derivative has m 229-232o. [Hahn & Wassmuth Chem Ber 67 2050 1934, UV: Lemon J Am Chem Soc 69 2998 1947 and Pearl & Beyer J Am Chem Soc 72 1743 1950, Beilstein 10 IV 1995.]
References
[1] H HARA. The 4-oxalomesaconate hydratase gene, involved in the protocatechuate 4,5-cleavage pathway, is essential to vanillate and syringate degradation in Sphingomonas paucimobilis SYK-6.[J]. Journal of Bacteriology, 2000, 182 24: 6950-6957. DOI: 10.1128/jb.182.24.6950-6957.2000
[2] MILENA COTORAS. In vitro and in vivo evaluation of the antioxidant and prooxidant activity of phenolic compounds obtained from grape (Vitis vinifera) pomace.[J]. Molecules, 2014, 19 12: 21154-21167. DOI: 10.3390/molecules191221154
[3] XIAOYONG WEI. Syringic Acid Extracted from Herba dendrobii Prevents Diabetic Cataract Pathogenesis by Inhibiting Aldose Reductase Activity.[J]. Evidence-based Complementary and Alternative Medicine, 2012, 2012: 426537. DOI: 10.1155/2012/426537
[4] KHALED Y ORABI. Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors.[J]. Cancer Cell International, 2013, 13 1: 82. DOI: 10.1186/1475-2867-13-82
[5] GANIYU OBOH. Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats’ pancreas by phenolic extracts of avocado pear leaves and fruit.[J]. International Journal of Biomedical Science: IJBS, 2014, 10 3: 208-216.
Syringic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from Syringic acid manufacturers
- Product
- Syringic acid 530-57-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000kg/Mouth
- Release date
- 2023-08-25
- Product
- Syringic acid 530-57-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-29
- Product
- Syringic acid 530-57-4
- Price
- US $1000.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10TONS
- Release date
- 2021-06-04