Estradiol benzoate

Product Name: Estradiol benzoate
CAS No.: 50-50-0
Chemical Name: Estradiol benzoate
Synonyms: ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;diogynb;ESTON-B;Diogyn B
CBNumber: CB9131644
Molecular Formula: C25H28O3
Formula Weight: 376.5
MOL File: 50-50-0.mol

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Estradiol benzoate Property

Melting point:: 191-198 °C(lit.)
alpha: D25 +58 to +63° (c = 2 in dioxane)
Boiling point:: 465.03°C (rough estimate)
Density: 1.0493 (rough estimate)
refractive index: 1.5460 (estimate)
storage temp.: 2-8°C
solubility: Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
pka: 15.06±0.40(Predicted)
form: Solid
color: White
Water Solubility: 0.4mg/L(25 ºC)
Merck: 3703
BRN: 3107526
CAS DataBase Reference: 50-50-0(CAS DataBase Reference)
NIST Chemistry Reference: Estradiol benzoate(50-50-0)

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Safety

Hazard Codes: T
Risk Statements: 60-61-40
Safety Statements: 53-22-36/37/39-45
WGK Germany: 3
RTECS: KG4050000
F: 8
HS Code: 29372319

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E8515
Product name: β-Estradiol 3-benzoate
Purity: ≥97%
Packaging: 1g
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2858
Product name: Estradiol Benzoate
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 500MG
Price: $286
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP396
Product name: Estradiol benzoate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 50MG
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1251000
Product name: Estradiol benzoate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 250mg
Price: $436
Updated: 2024/03/01

Cayman Chemical

Product number: 10006487
Product name: Estradiol Benzoate
Purity: ≥98%
Packaging: 500mg
Price: $32
Updated: 2024/03/01

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Estradiol benzoate Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

antiacne, antineoplastic

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.

Definition

ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.

Clinical Use

Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

Estradiol benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Estradiol benzoate Suppliers

Belgium 2 Brazil 2 Canada 2 China 323 Czech Republic 1 Europe 3 France 5 Germany 6 India 31 Japan 3 Slovakia 1 Spain 2 Switzerland 3 United Kingdom 8 United States 41 Uruguay 1 Venezuela 1 Global 435

Clearsynth Labs Limited

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View Lastest Price from Estradiol benzoate manufacturers

Sinoway Industrial co., ltd.

Product: estradiol benzoate 50-50-0
Price: US $0.00-0.00/Kg/Bag
Min. Order: 0.10000000149011612Kg/Bag
Purity: USP, GMP
Supply Ability: 2tons
Release date: 2024-06-27

Wuhan Haorong Biotechnology Co.,Ltd

Product: Estradiol benzoate 50-50-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500
Release date: 2023-07-31

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Estradiol benzoate 50-50-0
Price: US $0.00/g/Bag
Min. Order: 100g
Purity: 97.0~103.0%; USP43
Supply Ability: 800kg/month
Release date: 2021-06-03

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(8R,9S,13S,14S,17S)-17-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl benzoate

(1S,10R,11S,14R,15S)-5-hydroxy-15-Methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-yl benzoate

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Β-ESTRADIOL 3-BENZOATE

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Benovocylin

Benzestrofol

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