2-Chloro-3-cyanopyridine
- Product Name
- 2-Chloro-3-cyanopyridine
- CAS No.
- 6602-54-6
- Chemical Name
- 2-Chloro-3-cyanopyridine
- Synonyms
- 2-CHLORONICOTINONITRILE;2-Chloro-3-cyanopyri;2-CHLORONICOTINITRILE;3-cyano-2-chloropyridine;2-CHLORO-3-PYRIDINECARBONITRILE;NSC 73287;AKOS 93614;RARECHEM AH CK 0066;2-Chloronictinonitril;2-Chloronicotinotrile
- CBNumber
- CB2360357
- Molecular Formula
- C6H3ClN2
- Formula Weight
- 138.55
- MOL File
- 6602-54-6.mol
2-Chloro-3-cyanopyridine Property
- Melting point:
- 104-107 °C(lit.)
- Boiling point:
- 112°C 1mm
- Density
- 1.3185 (rough estimate)
- refractive index
- 1.4877 (estimate)
- Flash point:
- 112°C/1mm
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Crystalline Powder or Flakes
- pka
- -2.17±0.10(Predicted)
- color
- White to off-white
- BRN
- 115772
- InChI
- InChI=1S/C6H3ClN2/c7-6-5(4-8)2-1-3-9-6/h1-3H
- InChIKey
- JAUPUQRPBNDMDT-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=CC=C1C#N
- CAS DataBase Reference
- 6602-54-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-36/37/39
- RIDADR
- UN 3439 6.1/PG 3
- WGK Germany
- 3
- Hazard Note
- Toxic/Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29333990
- Storage Class
- 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects - Hazard Classifications
- Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 535338
- Product name
- 2-Chloro-3-pyridinecarbonitrile
- Purity
- 98%
- Packaging
- 25g
- Price
- $60.3
- Updated
- 2025/07/31
- Product number
- 535338
- Product name
- 2-Chloro-3-pyridinecarbonitrile
- Purity
- 98%
- Packaging
- 500g
- Price
- $195.26
- Updated
- 2025/07/31
- Product number
- C1369
- Product name
- 2-Chloro-3-cyanopyridine
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $28
- Updated
- 2025/07/31
- Product number
- C1369
- Product name
- 2-Chloro-3-cyanopyridine
- Purity
- >97.0%(GC)
- Packaging
- 500g
- Price
- $326
- Updated
- 2025/07/31
- Product number
- C365110
- Product name
- 2-Chloro-3-cyanopyridine
- Packaging
- 50g
- Price
- $1230
- Updated
- 2021/12/16
2-Chloro-3-cyanopyridine Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
2-Chloro-3-cyanopyridine (cas# 6602-54-6) is a compound useful in organic synthesis.
Synthesis
2-Chloro-3-cyanopyridine is synthesized from 3-cyanopyridine. First, 3-cyanopyridine is treated with 28-31% H2O2 solution. After standing, the mixture is evaporated to yield nicotinamide-N-oxide. This oxide is then reacted with POCl3 at 35-80??C. Additional POCl3 is added, and the mixture stands to form the chlorination solution. This solution undergoes reduced-pressure distillation. It is then cooled, and cold water is added. Filtration yields a solid phase. The solid is dissolved in a methanol-water system. Activated carbon is added for decolorization, followed by filtration. The filtrate is evaporated until crystals precipitate. Cooling gives the recrystallized product, which is finally dried under vacuum.
2-Chloro-3-cyanopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-3-cyanopyridine manufacturers
- Product
- 2-Chloro-3-cyanopyridine 6602-54-6
- Price
- US $0.00/KG
- Min. Order
- 25KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-07
- Product
- 2-Chloro-3-cyanopyridine 6602-54-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-05
- Product
- 2-Chloro-3-cyanopyridine 6602-54-6
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-04-24