4-PYRIDIN-3-YL-BENZOIC ACID

Product Name: 4-PYRIDIN-3-YL-BENZOIC ACID
CAS No.: 4385-75-5
Chemical Name: 4-PYRIDIN-3-YL-BENZOIC ACID
Synonyms: AKOS BAR-0406;4-PYRID-3-YLBENZOIC ACID;4-pyridin-3-ylbenzoicaci;4-(3-PYRIDYL)BENZOIC ACID;4-(3'-Pyridyl)benzoic Acid;4-PYRIDIN-3-YL-BENZOIC ACID;4-(3-PYRIDINYL)BENZOIC ACID;4-pyridine-3-yl-benzoic acid;4-Pyridin-3-ylbenzoicacid97%;4-Pyridin-3-yl-benzoicacid95%
CBNumber: CB6496269
Molecular Formula: C12H9NO2
Formula Weight: 199.21
MOL File: 4385-75-5.mol

More

Less

4-PYRIDIN-3-YL-BENZOIC ACID Property

Melting point:: 271-274
Boiling point:: 398.8±25.0 °C(Predicted)
Density: 1.241±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 3.65±0.10(Predicted)
color: White
InChI: InChI=1S/C12H9NO2/c14-12(15)10-5-3-9(4-6-10)11-2-1-7-13-8-11/h1-8H,(H,14,15)
InChIKey: GYUKEVKPDRXPAB-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=C(C2=CC=CN=C2)C=C1
CAS DataBase Reference: 4385-75-5(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Hazard Note: Harmful
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P992578
Product name: 4-(3''-Pyridyl)benzoicAcid
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 007710
Product name: 4-(3-Pyridinyl)benzoic acid
Purity: 97%
Packaging: 500mg
Price: $30
Updated: 2021/12/16

AK Scientific

Product number: W6300
Product name: 4-Pyridin-3-yl-benzoicacid
Packaging: 5g
Price: $111
Updated: 2021/12/16

ChemScene

Product number: CS-0036181
Product name: 4-Pyridin-3-ylbenzoicacid
Packaging: 5g
Price: $122
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-1-F3
Product name: 4-Pyridin-3-ylbenzoic acid
Purity: 97.0%
Packaging: 5G
Price: $144
Updated: 2021/12/16

More

Less

4-PYRIDIN-3-YL-BENZOIC ACID Chemical Properties,Usage,Production

Definition

ChEBI: 4-Pyrid-3-ylbenzoic acid is a phenylpyridine.

Synthesis

626-55-1

14047-29-1

4385-75-5

Example 157 Synthesis of 4-(pyridin-3-yl)benzoic acid: in a mixed solvent of acetonitrile (40 mL) and water (40 mL), 4-carboxyphenylboronic acid (1.66 g, 10 mmol), 3-bromopyridine (1.72 g, 11 mmol), potassium carbonate (5.5 g, 40 mmol), and bis(triphenylphosphine)palladium(II) chloride (400 mg. 0.37 mmol). The reaction mixture was degassed and displaced three times with nitrogen. Subsequently, the mixture was stirred under reflux conditions for 24 hours. Upon completion of the reaction, the reaction suspension was filtered while hot and the filtrate was concentrated to half of the original volume. The concentrated aqueous phase was washed with dichloromethane. The aqueous phase was adjusted to pH=3 with 1 M hydrochloric acid, the solid was precipitated, filtered and the solid was washed with water. Finally, the resulting solid was dried under vacuum to give 1.7 g of white solid 4-(pyridin-3-yl)benzoic acid in 85% yield.LC-MS (ESI) m/z: 200 (M+1)+.

References

[1] Patent: US2009/197863, 2009, A1. Location in patent: Page/Page column 73-74
[2] Archiv der Pharmazie, 2008, vol. 341, # 8, p. 478 - 484
[3] Synlett, 2000, # 6, p. 829 - 831
[4] Patent: US6399656, 2002, B1
[5] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 780 - 789

4-PYRIDIN-3-YL-BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-PYRIDIN-3-YL-BENZOIC ACID Suppliers

Belgium 1 Canada 1 China 63 France 1 Germany 4 India 1 Russia 1 United Kingdom 6 United States 16 Global 94

H-S Chemicals Co.,Ltd.

Tel: 18115673450
Email: sales@hschemicals.com
Country: China
ProdList: 9
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Shanghai Na Qian Chemical Technology Co. Ltd.

Tel: 13598610367
Fax: QQ:2468833170
Email: 2841375912@qq.com
Country: China
ProdList: 2786
Advantage: 52

More

Less

View Lastest Price from 4-PYRIDIN-3-YL-BENZOIC ACID manufacturers

Career Henan Chemical Co

Product: 4-PYRIDIN-3-YL-BENZOIC ACID 4385-75-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-11

4385-75-5, 4-PYRIDIN-3-YL-BENZOIC ACIDRelated Search:

4-(5-Methyl-2-pyridinyl)benzoic acid 4-PYRIDIN-3-YL-BENZOIC ACID 4-(6-(Trifluoromethyl)pyridin-2-yl)benzoic acid 4-Pyrid-4-ylbenzoic acid 1-(4-Trifluoromethylphenyl)piperidin-4-ol 3-(6-Bromopyridin-2-yl)benzoic acid 4-(4,4-DIMETHYL-PIPERIDIN-1-YL)-BENZOIC ACID 3-(5-NITROPYRIDIN-2-YL)BENZOIC ACID 3-PYRIDIN-2-YL-BENZOIC ACID, 95+% 4-(2-Pyridyl)benzoic acid 3-Pyridin-3-yl-benzoic acid ,97% 4-(3-QUINOLINYL)BENZOIC ACID METHYL 4-(3-PYRIDINYL)BENZOATE METHYL 4-(6-METHOXY-3-PYRIDINYL)BENZOATE 4-(6-AMINO-PYRIDIN-3-YL)-BENZOIC ACID 4-(4-(Methoxycarbonyl)pyridin-3-yl)benzoic acid,4-(6-(Methoxycarbonyl)pyridin-3-yl)benzoic acid,4-(5-(Methoxycarbonyl)pyridin-3-yl)benzoic acid 3-(6-(Methoxycarbonyl)pyridin-3-yl)benzoic acid,3-(5-(Methoxycarbonyl)pyridin-3-yl)benzoic acid 4-[3-[2-(Dimethylamino-d6)-2-oxoethyl]-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic Acid

AKOS BAR-0406

4-(3-PYRIDINYL)BENZOIC ACID

4-(3-PYRIDYL)BENZOIC ACID

4-PYRIDIN-3-YL-BENZOIC ACID

4-PYRID-3-YLBENZOIC ACID

4-Pyridin-3-yl-benzoicacid95%

4-Pyridin-3-ylbenzoic acid 97%

4-(2-Chloropyridin-3-yl)benzoic acid

4-(2-Fluoropyridin-3-yl)benzoic acid

4-(5-Fluoropyridin-3-yl)benzoic acid

4-(6-Fluoropyridin-3-yl)benzoic acid

4-pyridine-3-yl-benzoic acid

Benzoic acid, 4-(3-pyridinyl)-

4-Pyridin-3-ylbenzoicacid97%

4-(pyridin-3-yl)benzoic acid hydrochloride

4-(3'-Pyridyl)benzoic Acid

4-pyridin-3-ylbenzoicaci

4385-75-5

Building Blocks

Carboxy

Pyridine

pharmacetical

API intermediates