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KF31327

Product Name
KF31327
CAS No.
220060-39-9
Chemical Name
KF31327
Synonyms
KF31327;Thioquinapiperfil;KF-31327 free base;Thioquinapiperifil;3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione;2H-Imidazo[4,5-g]quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-[[[2-[4-(hydroxymethyl)-1-piperidinyl]phenyl]methyl]amino]-
CBNumber
CB02104148
Molecular Formula
C24H28N6OS
Formula Weight
448.58
MOL File
220060-39-9.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0001267
Product name
KF31327
Purity
95.00%
Packaging
5MG
Price
$499.51
Updated
2021/12/16
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KF31327 Chemical Properties,Usage,Production

Biological Activity

Thioquinapiperifil (KF31327 free base) is a potent, selective, and noncompetitive inhibitor of phosphodiesterase (PDE-5) (IC50 of 0.074 nM) for sexual maturation studies.

in vitro

Thioquinapiperifil can be found in dietary supplements. Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation.

target

PDE5

0.074 nM (IC 50 )

PDE1

380 nM (IC 50 )

PDE2

670 nM (IC 50 )

PDE3

38 nM ( IC 50 )

PDE4

800 nM (IC 50 )

KF31327 Preparation Products And Raw materials

Raw materials

Preparation Products

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KF31327 Suppliers

ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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Wuhan Greenkj Pharmaceutical Technology Co., Ltd.
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15608630565
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greenkjpharm@163.com
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Shenzhen SUNGENING Bio-Medical Co., Ltd.
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0755-28967200 13631290199
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wxf@sungening.com
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 13028896684
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sales@rrkchem.com
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TCI (Shanghai) Chemical Trading Co., Ltd.
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021-61109150
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021-61105897
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sales@tcisct.com
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840
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psaitong@jm-bio.com
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China
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TargetMol Chemicals Inc.
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4008200310
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Shenzhen Qingtian Biotechnology Co, Ltd.
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18823167005 18162969855
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Nantong Hanfang Biotechnology Co. , Ltd.
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3674309880
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hanfangpharma@126.com
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China
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Shanghai Ziqi Biological Technology Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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