Sildenafil Chlorosulfonyl

Product Name: Sildenafil Chlorosulfonyl
CAS No.: 139756-22-2
Chemical Name: Sildenafil Chlorosulfonyl
Synonyms: Sildenafil Impurity 7;Methisosildenafil-004;Sildenafil　intermediate;Sildenafil Chlorosulfone;Sildenafil chlorosulfonyl;Methisosildenafil Impurity 33;Sildenafil Chlorosulfone IMpurity;Sildenafil Chlorosulfonyl IMpurity;5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1-;4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro
CBNumber: CB11175931
Molecular Formula: C17H19ClN4O4S
Formula Weight: 410.88
MOL File: 139756-22-2.mol

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Sildenafil Chlorosulfonyl Property

Melting point:: 180-182°C
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 9.87±0.20(Predicted)
color: White to Pale Beige
Stability:: Moisture Sensitive
InChI: InChI=1S/C17H19ClN4O4S/c1-4-6-12-14-15(22(3)21-12)17(23)20-16(19-14)11-9-10(27(18,24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,19,20,23)
InChIKey: RVVOSOSBFSYZDM-UHFFFAOYSA-N
SMILES: C1(S(Cl)(=O)=O)=CC=C(OCC)C(C2NC(=O)C3N(C)N=C(CCC)C=3N=2)=C1
CAS DataBase Reference: 139756-22-2

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

TRC

Product number: C380005
Product name: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Packaging: 250mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C380005
Product name: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Packaging: 2.5g
Price: $195
Updated: 2021/12/16

TRC

Product number: C380005
Product name: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Packaging: 1g
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20392
Product name: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Packaging: 50mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20392
Product name: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Packaging: 100mg
Price: $160
Updated: 2021/12/16

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Sildenafil Chlorosulfonyl Chemical Properties,Usage,Production

Description

Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil. It is also a potential impurity found in commercial preparations of sildenafil.

Chemical Properties

Off-White Solid

Uses

The compound Sildenafil Chlorosulfonyl Impurity (139756-22-2) is a derivative of Sildenafil. It is widely used in the treatment of pulmonary hypertension as it is capable of inhibiting cGMP and acts as a potent selective inhibitor of PDE5.

Sildenafil Chlorosulfonyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Sildenafil Chlorosulfonyl Suppliers

Canada 1 China 128 India 10 United Kingdom 1 United States 13 Global 153

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
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ProdList: 1212
Advantage: 58

Xianning Shen Lan Biomedical Research and Development Co., Ltd.

Tel: 18171815831
Email: 1341138380@qq.com
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Shanghai Raise Chemical Technology Co.,Ltd

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Country: China
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Advantage: 55

J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Adamas Reagent, Ltd.

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Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Daicel Chiral Technologies (China)CO.,LTD

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Tianjin heowns Biochemical Technology Co., Ltd.

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BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
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View Lastest Price from Sildenafil Chlorosulfonyl manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonyl chloride 139756-22-2
Price: US $100.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 2 tons
Release date: 2023-09-04

Career Henan Chemical Co

Product: 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 139756-22-2
Price: US $3.00/KG
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 100kg
Release date: 2019-09-03

139756-22-2, Sildenafil ChlorosulfonylRelated Search:

Tofacitinib citrate 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-(5-chloro-2-ethoxyphenyl)-1,6-dihydro-1-methyl-3-propyl- KF31327 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID 2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]BENZOIC ACID 1-Piperazinesulfonicacid,4-methyl-(9CI) Lidocaine Impurity MONOETHYLGLYCINEXYLIDIDE Nor Lidocaine Hydrochloride N-(2,6-DIMETHYLPHENYL)-2-(METHYLAMINO)ACETAMIDE HYDROCHLORIDE Methisosildenafil impure Acotiamide Impurity Terazosin EP Impurity O Methisosildenafil Impurity 7,8-Dihydro-14-hydroxy- normorphinone Methyl 2-(2-hydroxy-4,5-diMethoxybenzaMido)thiazole-4-carboxylate Donepezil Impurity 3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester

3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1 H-pyrazolo-(4-3-d)-pyrimidine-5

3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-benzenesulfonyl Chloride

5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

5-(5-CHLOROSULFONYL-2-ETHOXY PHENYL)-1-METHYL-3-N-PROPYL-1

Sildenafil Chlorosulfonyl IMpurity

4-Ethoxy-3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyriMidin-5-yl)benzene-1-sulfonyl chloride

Sildenafil Chlorosulfone IMpurity

4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo

4-Ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzene-1-sulfonyl chloride

Sildenafil　intermediate

4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)

4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-su

Sildenafil Impurity 7

Methisosildenafil-004

5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazole[4,3-d]pyrimidine-7-one

Sildenafil impurity 33/Sildenafil Chlorosulfonyl/Sildenafil Chlorosulfone Impurity/5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazole[4,3-d]pyrimidine-7-one

4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro

5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1-

5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1- METHYL-3-PROPYL-1 6-DIHYDRO-7H-PYRAZOL O-(4 3-D)PYRIMIDINE-7-ONE

Methisosildenafil Impurity 33

Benzenesulfonyl chloride, 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-

Demethylpiperazinyl sildenafil sulfonyl chloride

4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonyl chloride

5-(5-CHLORO SULFONYL-2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO-[4,3,D]-PYRIMIDINE-7-ONE

5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-Chemicalbookpropyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-di...

Sildenafil Chlorosulfone

Sildenafil Chlorosulfonyl (5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one)

Sildenafil chlorosulfonyl

4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo4,3-dpyrimidin-5-yl)benzene-1-sulfonyl chloride

139756-22-2

Bases & Related Reagents

Nucleotides

Sulfonyl Chlorides