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S(-)-VERAPAMIL

Product Name
S(-)-VERAPAMIL
CAS No.
36622-28-3
Chemical Name
S(-)-VERAPAMIL
Synonyms
LU 33926;S(-)-VERAPAMIL;S-Verapamil HCL;S(-)-VERAPAMIL HYDROCHLORIDE;S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE;S(-)-Verapamil hydrate hydrochloride;(S)Verapamil hydrochloride,(S) Verapamil hydrochloride;[7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride;(-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride;(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile:hydrochloride
CBNumber
CB0211785
Molecular Formula
C27H38N2O4
Formula Weight
454.6
MOL File
36622-28-3.mol
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S(-)-VERAPAMIL Property

Melting point:
131-133 °C
solubility 
H2O: >30 mg/mL
form 
solid
color 
white
optical activity
[α]22/D 6.1°, c = 0.1 in ethanol(lit.)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
V105
Product name
S(?)-Verapamil hydrochloride hydrate
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$398
Updated
2024/03/01
Sigma-Aldrich
Product number
V105
Product name
S(?)-Verapamil hydrochloride hydrate
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$1600
Updated
2024/03/01
TRC
Product number
V124991
Product name
(S)-(-)-VerapamilHydrochloride
Packaging
1mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-0111669
Product name
(S)-Verapamil(hydrochloride)
Purity
99.39%
Packaging
5mg
Price
$250
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D75313
Product name
(S)-(-)-Verapamil-d3HCl(N-methyl-d3)
Packaging
5mg
Price
$750
Updated
2021/12/16
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S(-)-VERAPAMIL Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.

Definition

ChEBI: (S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.

Biochem/physiol Actions

Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.

S(-)-VERAPAMIL Preparation Products And Raw materials

Raw materials

Preparation Products

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S(-)-VERAPAMIL Suppliers

Canada 1 China 33 Germany 1 India 3 Switzerland 1 United Kingdom 4 United States 12 Global 55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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69
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6818
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65
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3421
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3066
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58

36622-28-3, S(-)-VERAPAMILRelated Search:

R(+)-VERAPAMIL HYDROCHLORIDE,(+)-VERAPAMIL, METHOXY-, HYDROCHLORIDE (+/-)-VERAPAMIL, NOR-METHYL-, HYDROCHLORIDE R(+)-VERAPAMIL HYDROCHLORIDE,(+)-VERAPAMIL, METHOXY-, HYDROCHLORIDE VERAPAMIL RELATED COMPOUND B (50 MG) (AL-PHA-[2-[[2-(3,4-DIMETHOXYPHENYL)-ETHYL]METHYLA-MINO]ETHYL]-3,4-DIMETHOXY-ALPHA-(1-METHY-LETHYL)-BENZENEACETONITRILE MONOHYDROCHLORIDE) Verapamil Impurity O 3,4-Dimethoxy-N-methylphenethylamine hydrochloride Verapamil Impurity N N,N'-Vis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride VERAPAMIL RELATED COMPOUND D (50 MG) (5,5'-[[2-(3,4)DIMETHOXYPHENYL)ETHYL]IMINO]BIS[2-(3,4-DIMETHOXYPHENYL)-2-(1-METHYLETHYL)PENTANENI-TRILE] HYDROCHLORIDE) NSC 609249 Verapamil Related Compound A (50 mg) (3,4-Dimethoxy-alpha-[3-(methylamino)propyl]-alpha-(1-methylethyl)-benzeneacetonitrile monohydrochloride) alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-alpha-ethyl-3,4-dimethoxybenzeneacetonitrile monohydrochloride 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile N-Methyl-N-(3-chloropropyl)-3,4-dimethoxyphenethylamine (3,4-Dimethoxyphenyl)isopropyl ketone RAC D 617 (N-METHYL-4-(3,4-DIMETHOXYPHENYL)-4-CYANO-5-METHYLHEXYLAMINE) Verapamil Impurity P D 620

  • S(-)-VERAPAMIL
  • S(-)-VERAPAMIL HYDROCHLORIDE
  • S-Verapamil HCL
  • [7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride
  • (-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride
  • S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE
  • Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (aS)- (9CI)
  • Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (S)-
  • LU 33926
  • Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl) ethyl]methylamino]propyl]-3,4-dimethoxy -α-(1-methylethyl)-, monohydrochloride, (αS)-
  • S(-)-Verapamil hydrate hydrochloride
  • (2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile:hydrochloride
  • (S)Verapamil hydrochloride,(S) Verapamil hydrochloride
  • 36622-28-3
  • C27H38N2O4HClxH2O
  • BioChemical
  • Cell Biology
  • Calcium Channel Modulators
  • Cell Signaling and Neuroscience
  • Ion Channels
  • Voltage-gated Ion Channels
  • Calcium Channel Modulators
  • Verapamil
  • Voltage-gated Ion Channels
  • Organics