ChemicalBook > CAS DataBase List > NORVERAPAMIL HYDROCHLORIDE

NORVERAPAMIL HYDROCHLORIDE

Product Name
NORVERAPAMIL HYDROCHLORIDE
CAS No.
67812-42-4
Chemical Name
NORVERAPAMIL HYDROCHLORIDE
Synonyms
NORVERAPAMIL HCL;D591 hydrochloride;Verapamil EP Impurity J;Verapamil Impurity J HCl;NORVERAPAMIL HYDROCHLORIDE;Verapamil EP Impurity J HCl;(+)Norverapamil hydrochloride;(+/-)-Norverapamil hydrochloride;n-nor-(±)-verapamil hydrochloride;(±)-Norverapamill hydrochloride solution
CBNumber
CB8331256
Molecular Formula
C26H37ClN2O4
Formula Weight
477.04
MOL File
67812-42-4.mol
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NORVERAPAMIL HYDROCHLORIDE Property

Melting point:
softens at 50°C, 155-160°C dec.
Flash point:
9℃
storage temp. 
desiccated
solubility 
H2O: >10 mg/mL
form 
solid
color 
white
Stability:
Hygroscopic
EPA Substance Registry System
Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, hydrochloride (1:1) (67812-42-4)
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Safety

RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
V108
Product name
(±)-Norverapamil hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$196.8
Updated
2024/03/01
Sigma-Aldrich
Product number
N-112
Product name
(±)-Norverapamill hydrochloride solution
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$150
Updated
2022/05/15
Cayman Chemical
Product number
20950
Product name
Norverapamil (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20950
Product name
Norverapamil (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
20950
Product name
Norverapamil (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$243
Updated
2024/03/01
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NORVERAPAMIL HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Uses

Nor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.

General Description

Norverapamil is a primary urinary metabolite of verapamil, a calcium channel blocker used in the treatment of hypertension, angina pectoris, and cardiac arrhythmia. Verapamil is also an effective preventive medication for migraines. This Certified Reference Material is applicable for use as starting material in calibrators or controls for verapamil testing methods by LC-MS/MS or GC-MS.

Biochem/physiol Actions

Norverapamil is an N-demethylated metabolite of verapamil. It has significantly less calcium channel blocking ability and exhibit therapeutic activity.

NORVERAPAMIL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NORVERAPAMIL HYDROCHLORIDE Suppliers

Canada 3 China 63 Germany 1 India 5 Switzerland 1 United Kingdom 1 United States 13 Global 87
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1735
Advantage
55
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1958
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3066
Advantage
58
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View Lastest Price from NORVERAPAMIL HYDROCHLORIDE manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
(+)Norverapamil hydrochloride 67812-42-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
NORVERAPAMIL HYDROCHLORIDE 67812-42-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
NORVERAPAMIL HYDROCHLORIDE 67812-42-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

67812-42-4, NORVERAPAMIL HYDROCHLORIDERelated Search:

DAURICINE Quinidine PILSICAINIDE Linocaine hydrochloride (+/-)-Verapamil hydrochloride Decloxizin HCL CP2000 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-alpha-ethyl-3,4-dimethoxybenzeneacetonitrile monohydrochloride Verapamil Related Compound A (50 mg) (3,4-Dimethoxy-alpha-[3-(methylamino)propyl]-alpha-(1-methylethyl)-benzeneacetonitrile monohydrochloride) NSC 609249 VERAPAMIL RELATED COMPOUND D (50 MG) (5,5'-[[2-(3,4)DIMETHOXYPHENYL)ETHYL]IMINO]BIS[2-(3,4-DIMETHOXYPHENYL)-2-(1-METHYLETHYL)PENTANENI-TRILE] HYDROCHLORIDE) N,N'-Vis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride 3,4-Dimethoxy-N-methylphenethylamine hydrochloride Verapamil Impurity O N-Methyl-N-(3-chloropropyl)-3,4-dimethoxyphenethylamine (3,4-Dimethoxyphenyl)isopropyl ketone S(-)-VERAPAMIL VERAPAMIL RELATED COMPOUND B (50 MG) (AL-PHA-[2-[[2-(3,4-DIMETHOXYPHENYL)-ETHYL]METHYLA-MINO]ETHYL]-3,4-DIMETHOXY-ALPHA-(1-METHY-LETHYL)-BENZENEACETONITRILE MONOHYDROCHLORIDE)

  • NORVERAPAMIL HCL
  • NORVERAPAMIL HYDROCHLORIDE
  • (+/-)-VERAPAMIL, NOR-METHYL-, HYDROCHLORIDE
  • a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- benzeneacetonitril
  • n-nor-(±)-verapamil hydrochloride
  • α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile
  • (+-)-VERAPAMIL HYDROCHLORIDE, NOR-METHYL (NORVERAPAMIL HYDROCH
  • a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile
  • NorverapaMil HCl (N-DesMethyl VerapaMil HCl)
  • (±)-Norverapamill hydrochloride solution
  • Verapamil Impurity J HCl
  • (±)-NORVERAPAMIL HYDROCHLORIDE;D591 HYDROCHLORIDE
  • D591 hydrochloride
  • 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile,hydrochloride
  • Verapamil EP Impurity J
  • Verapamil Impurity 10（Verapamil EP Impurity J）
  • Verapamil EP Impurity J HCl (N-Desmethyl Verapamil HCl)
  • (+/-)-Norverapamil hydrochloride
  • (+/-)-Norverapamill hydrochloride solution
  • Verapamil EP Impurity J HCl
  • Norverapamil HydrochlorideQ: What is Norverapamil Hydrochloride Q: What is the CAS Number of Norverapamil Hydrochloride Q: What is the storage condition of Norverapamil Hydrochloride Q: What are the applications of Norverapamil Hydrochloride
  • MDR1,CD243,Inhibitor,mycobacterial,Norverapamil,M. tuberculosis,Multidrug resistance protein 1,Ca2+ channels,metabolite,(±)-Norverapamil,P-gp,Calcium Channel,efflux,Ca channels,Drug Metabolite,P-glycoprotein,inhibit,ABCB1,Cluster of differentiation 243,D 591,Norverapamil hydrochloride,pumps,D-591,D591,Pgp
  • (+)Norverapamil hydrochloride
  • 67812-42-4
  • 670018-85-3
  • C26H36N2O4HCl
  • Ion Channels
  • Voltage-gated Ion Channels
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Calcium Channel Modulators
  • BioChemical
  • Metabolites
  • Various Metabolites and Impurities