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Sulconazle Nitrate

Product Name
Sulconazle Nitrate
CAS No.
82382-23-8
Chemical Name
Sulconazle Nitrate
Synonyms
Sulcozle Nitrate;Sulconazle Nitrate;SULCONAZOLE NITRATE;(±)-Sulconazole nitrat;Sulconazle Nitrate USP/EP/BP;SULCONAZOLE NITRATE FPC(CRM STANDARD) USP/EP/BP;1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
CBNumber
CB02131212
Molecular Formula
C18H15Cl3N2S.HNO3
Formula Weight
460.76
MOL File
82382-23-8.mol
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Sulconazle Nitrate Property

Melting point:
148-153°C
storage temp. 
Refrigerator
solubility 
Acetonitrile (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
82382-23-8
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
J98556
Product name
Sulconazole nitrate
Packaging
1g
Price
$95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007242
Product name
Sulconazole nitrate
Purity
95.00%
Packaging
50MG
Price
$224.7
Updated
2021/12/16
AK Scientific
Product number
K466
Product name
Sulconazole nitrate
Packaging
5g
Price
$394
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007242
Product name
Sulconazole nitrate
Purity
95.00%
Packaging
1G
Price
$638.39
Updated
2021/12/16
AK Scientific
Product number
K466
Product name
Sulconazole nitrate
Packaging
10g
Price
$641
Updated
2021/12/16
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Sulconazle Nitrate Chemical Properties,Usage,Production

Description

Sulconazole nitrate is an imidazole antifungal agent closely related to econazole. It is effective in the topical treatment of a broad spectrum of superficial fungal infections.

Originator

Syntex (USA)

Uses

Antifungal.

Definition

ChEBI: Sulconazole nitrate is an organic nitrate salt, a conazole antifungal drug and an imidazole antifungal drug.

brand name

Exelderm (Westwood-Squibb).

Biological Activity

Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.

Clinical Use

1-[2,4-Dichloro-β-[p-chlorobenzyl)thio]phenethyl]imidazolemononitrate (Exelderm) is the white crystalline nitricacid salt of sulconazole. It is sparingly soluble in water butsoluble in ethanol. The salt is used in a solution and a cream in 1% concentration for the treatment of local tinea infections,such as jock itch, athlete’s foot, and ringworm.

in vitro

Sulconazole Nitrate possesses a broad spectrum of activity in vitro against dermatophytes, yeasts and some Gram-positive bacteria at concentrations below 5 mg/L in vitro. It has been shown that against representatives of pathogenic yeasts, dermatophytes and Aspergilli, the RIF values of sulconazole are broadly similar to those of other imidazoles. The fungicidal potency of sulconazole in vitro depends on its concentration and on the growth phase of the inoculum cells. Sulconazole has also demonstrated antibacterial activity in vitro, with MIC values below 12.5 mg/L.

in vivo

The efficacy and safety of sulconazole 1% cream has been demonstrated in controlled clinical studies in patients with superficial dermatophyte or yeast infections. To minimise the risk of reinfection treatment should continue for 3 weeks in Candida infections, tinea cruris, tinea corporis and pityriasis versicolor, and for 4 weeks in patients with tinea pedis.

Sulconazle Nitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sulconazle Nitrate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Sulconazole nitrate 82382-23-8
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-05-12
Hebei Duling International Trade Co. LTD
Product
Sulconazle Nitrate 82382-23-8
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-03-28
Hebei Duling International Trade Co. LTD
Product
Sulconazle Nitrate 82382-23-8
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-03-28

82382-23-8, Sulconazle NitrateRelated Search:


  • SULCONAZOLE NITRATE
  • 1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
  • Sulconazle Nitrate
  • Sulcozle Nitrate
  • (±)-Sulconazole nitrat
  • SULCONAZOLE NITRATE FPC(CRM STANDARD) USP/EP/BP
  • Sulconazle Nitrate USP/EP/BP
  • 82382-23-8
  • API