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Isoconazole nitrate

Product Name
Isoconazole nitrate
CAS No.
24168-96-5
Chemical Name
Isoconazole nitrate
Synonyms
Fazol;R 15454;Travogyn;Travogen;Adestan G 100;Gyno-Travogen;Gyno-travozen;ISOCONAZOLE NITRATE;Econazole Impurity D;IsoconazoleNitrate>
CBNumber
CB5317271
Molecular Formula
C18H15Cl4N3O4
Formula Weight
479.14
MOL File
24168-96-5.mol
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Isoconazole nitrate Property

Melting point:
178-182°C
storage temp. 
Sealed in dry,2-8°C
solubility 
Very slightly soluble in water, soluble in methanol, slightly soluble in ethanol (96 per cent).
form 
Solid
color 
White to Off-White
Merck 
14,5160
CAS DataBase Reference
24168-96-5(CAS DataBase Reference)
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Safety

RIDADR 
UN3077
RTECS 
NI4772000
HS Code 
2933.29.4300
HazardClass 
9
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2232
Product name
Econazole Impurity D
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500MG
Price
$73.5
Updated
2025/07/31
Sigma-Aldrich
Product number
I0380000
Product name
Isoconazole nitrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
150 mg
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
I0380000
Product name
Isoconazole nitrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
i0380000
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
I0834
Product name
Isoconazole Nitrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$79
Updated
2025/07/31
TCI Chemical
Product number
I0834
Product name
Isoconazole Nitrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$222
Updated
2022/04/27
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Isoconazole nitrate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Fazol,Fournier,France,1979

Uses

Antibacterial; antifungal

Uses

Isoconazole Nitrate acts as an antibacterial in the local treatment of vaginitis; antifungal agent (1,2).

Manufacturing Process

To a stirred and refluxing solution of 40 parts of benzene and 35 parts of dimethylformamide (both solvents previously dried azeotropically) are added successively 1.6 parts of sodium hydride and 7.7 parts of α-(2,4- dichlorophenyl)imidazole-1-ethanol, (cooling on ice is necessary). After the addition is complete, stirring and refluxing is continued for 30 minutes. Then there are added 7.8 parts of 2.6-dichlorobenzyl chloride and the whole is stirred at reflux for another 3 hours. The reaction mixture is poured onto water and the product 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl] imidazole, is extracted with benzene. The extract is washed twice with water, dried, filtered and evaporated in vacuo. The base residue is dissolved in a mixture of acetone and diisopropyl ether and to this solution is added an excess of concentrated nitric acid solution. The precipitated nitrate salt is filtered off and recrystallized from a mixture of methanol and diisopropyl ether, yielding 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl]imidazole nitrate; melting point 179°C.

Therapeutic Function

Antibacterial, Antifungal

Isoconazole nitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Isoconazole nitrate Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768836
Email
1791901229@qq.com
Country
China
ProdList
6950
Advantage
52
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5158
Advantage
50
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from Isoconazole nitrate manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
Isoconazole nitrate 24168-96-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-11-20
Shaanxi Dideu Medichem Co. Ltd
Product
Isoconazole nitrate 24168-96-5
Price
US $1.00-4.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2025-05-14
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Isoconazole Nitrate 24168-96-5
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-21

24168-96-5, Isoconazole nitrate Related Search:


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  • 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazolium nitrate
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  • Adestan G 100
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  • 24168-96-5
  • 168-96-5
  • C18H14Cl4N2OHNO3C18H15Cl4N3O4
  • C18H14Cl4N20HNO3
  • Inhibitors
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Antifungal