FR 139317

Product Name: FR 139317
CAS No.: 142375-60-8
Chemical Name: FR 139317
Synonyms: FR 139317;FR139317,CID107810;FR 139317, ETA receptor antagonist;N,N-hexamethylenecarbamoyl-leu-N-*methyl-D-trp-D-;(N,N-HEXAMETHYLENE) CARBAMOYL-LEU-D-TRP(N-ME)-D-2-PYA;(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL;(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH;D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-;N-[N-[N-[(HEXAHYDRO-1H-AZEPIN-1-YL)CARBONYL]-L-LEUCYL]-1-METHYL-D-TRYPTOPHYL]-3-(2-PYRIDINYL)-D-ALANINE;D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-
CBNumber: CB0216568
Molecular Formula: C33H44N6O5
Formula Weight: 604.74
MOL File: 142375-60-8.mol

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FR 139317 Property

Boiling point:: 943.9±65.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Desiccate at +4°C
solubility: Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
form: Powder
pka: 2.68±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B5082
Product name: FR 139317
Packaging: 10mg
Price: $378
Updated: 2026/05/06

ApexBio Technology

Product number: B5082
Product name: FR 139317
Packaging: 50mg
Price: $1562
Updated: 2026/05/06

Tocris

Product number: 1210
Product name: FR139317
Purity: ≥99%(HPLC)
Packaging: 10
Price: $234
Updated: 2021/12/16

Tocris

Product number: 1210
Product name: FR139317
Purity: ≥99%(HPLC)
Packaging: 50
Price: $964
Updated: 2021/12/16

Usbiological

Product number: 255334
Product name: FR 139317
Packaging: 10mg
Price: $502
Updated: 2021/12/16

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FR 139317 Chemical Properties,Usage,Production

Uses

FR 139317 is a novel, potent endothelin ETA receptor antagonist.

Biological Activity

A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .

IC 50

ET_A

FR 139317 Preparation Products And Raw materials

Raw materials

Preparation Products

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FR 139317 Suppliers

China 29 France 1 Germany 1 Switzerland 1 United Kingdom 2 United States 10 Global 44

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 89686
Advantage: 60

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9976
Advantage: 55

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7617
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32466
Advantage: 58

142375-60-8, FR 139317Related Search:

3-(2-Pyridyl)-D-alanine BETA-(2-PYRIDYL)-DL-ALANINE 2-Pyridinepropanol 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 FR 139317 2-(2-Methoxyphenoxy)ethylamine 1-METHYL-2-PYRIDIN-2-YL-ETHYLAMINE N-ACETYL-D-ALA-D-ALA 1H-Azepine-1-carboxamide,hexahydro-(9CI) METHYL-(1-METHYL-2-PYRIDIN-2-YL-ETHYL)-AMINE

FR 139317

(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL

(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH

2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid

D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-

D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-

(2R)-2-[[(2R)-2-[[(2S)-2-(AZEPANE-1-CARBONYLAMINO)-4-METHYLPENTANOYL]AMINO]-3-(1-METHYLINDOL-3-YL)PROPANOYL]AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID

FR139317,CID107810

N-[N-[N-[(HEXAHYDRO-1H-AZEPIN-1-YL)CARBONYL]-L-LEUCYL]-1-METHYL-D-TRYPTOPHYL]-3-(2-PYRIDINYL)-D-ALANINE

(N,N-HEXAMETHYLENE) CARBAMOYL-LEU-D-TRP(N-ME)-D-2-PYA

N,N-hexamethylenecarbamoyl-leu-N-*methyl-D-trp-D-

FR 139317, ETA receptor antagonist

(2R)-2-[[(2R)-2-([(2S)-2-[(1-AZEPANYLCARBONYL)AMINO]-4-METHYLPENTANOYL]AMINO)-3-(1-METHYL-1H-INDOL-3-YL)PROPANOYL]AMINO]-3-(2-PYRIDINYL)PROPANOIC ACID

142375-60-8

C33H44N6O5