ChemicalBook > CAS DataBase List > 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4

3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4

Product Name
3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4
CAS No.
15197-75-8
Chemical Name
3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4
Synonyms
2-Pyridylpropanoic acid;2-PYRIDINEPROPANOIC ACID;3-(2-Pyridinyl)propanoic acid;3-(2-Pyridyl)propionicacid,97%;2-(3-Pyridyl)propionic acid, 97%;3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4;2-Pyridinepropanoic acid (9CI, ACI);3-Pyridin-2-yl-propionic acid sulfate;3-Pyridin-2-yl-propionic acid H2SO4 ,95%;3-Pyridin-2-yl-propionic acid sulfuric acid
CBNumber
CB3335552
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
15197-75-8.mol
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3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 Property

Melting point:
140-145°C
Boiling point:
287.4±15.0 °C(Predicted)
Density 
1.193±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
solid
pka
3.87±0.10(Predicted)
color 
Light brown
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
760226
Product name
2-Pyridinepropionic acid
Purity
97%
Packaging
1g
Price
$171.35
Updated
2025/07/31
TRC
Product number
B525688
Product name
3-Pyridin-2-ylpropanoicAcid
Packaging
25mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR909092
Product name
3-(Pyridin-2-yl)propanoicacid
Purity
98%
Packaging
1g
Price
$130
Updated
2021/12/16
Apolloscientific
Product number
OR909092
Product name
3-(Pyridin-2-yl)propanoicacid
Purity
98%
Packaging
10g
Price
$595
Updated
2021/12/16
AK Scientific
Product number
V3472
Product name
3-(Pyridin-2-yl)propanoicacid
Packaging
10g
Price
$663
Updated
2021/12/16
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3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 Chemical Properties,Usage,Production

Synthesis

2859-68-9

15197-75-8

The general procedure for the synthesis of 3-pyridin-2-yl-propanoic acid from 3-(pyridin-2-yl)propan-1-ol was as follows: 3-(2-pyridinyl)-propanol (1 g, 7.6 mmol), water (13 mL), and concentrated sulfuric acid (0.59 mL, 5.1 mmol) were added to a 50 mL round-bottom flask equipped with a stirrer. Potassium permanganate (1.8 g, 11.3 mmol) was added to the stirring reaction mixture in batches over a period of 30 min while the reaction temperature was controlled at 50 °C. After the addition was completed, the reaction continued to be stirred at 50 °C until the color of the mixture changed to brown. Subsequently, the reaction mixture was warmed up to 80 °C and heated for 1 h. After completion of the reaction, it was filtered. The filtrate was concentrated to dryness under reduced pressure to afford the crude product 3-(2-pyridyl)-propionic acid (1.14 g), which could be used directly in the next step of the reaction without further purification. To obtain the pure product, the above crude product was dissolved in ethanol (10 mL), activated charcoal (0.1 g) was added, refluxed for 5 min and then hot filtered. The filtrate was cooled and crystallized to give pure 3-(2-pyridyl)-propionic acid (0.88 g, 78% yield).

References

[1] ACS Catalysis, 2018, vol. 8, # 7, p. 6738 - 6744
[2] Patent: US6162927, 2000, A
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 22, p. 9156 - 9169
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 3156,3167
[5] Organic Process Research and Development, 2017, vol. 21, # 9, p. 1388 - 1393

3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 Preparation Products And Raw materials

Raw materials

Preparation Products

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3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 Suppliers

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View Lastest Price from 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 manufacturers

Career Henan Chemical Co
Product
3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 15197-75-8
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2019-12-26

15197-75-8, 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4Related Search:


  • 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4
  • 3-(2-Pyridinyl)propanoic acid
  • 2-PYRIDINEPROPANOIC ACID
  • 2-Pyridylpropanoic acid
  • 3-Pyridin-2-yl-propionic acid sulfate
  • 3-Pyridin-2-yl-propionic acid H2SO4 ,95%
  • 3-pyridin-2-ylpropanoic acid(SALTDATA: 0.02Na2SO4)
  • 3-Pyridin-2-yl-propionic acid sulfuric acid
  • 2-(3-Pyridyl)propionic acid, 97%
  • 3-(2-Pyridyl)propionicacid,97%
  • 2-Pyridinepropanoic acid (9CI, ACI)
  • 15197-75-8
  • C8H9NO2H2SO4
  • pharmacetical