9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
- Product Name
- 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
- CAS No.
- 209860-88-8
- Chemical Name
- 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
- Synonyms
- AFP-172;209860-84-1;tafluprost acid;Tafluprost Impurity 9;TAFLUPROST (FREE ACID);Tafluprost Impurity DCP-1;Tafluoroprostaglandin impurity;Tafluprost Impurity Tafluprost acid;7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid;9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
- CBNumber
- CB0224547
- Molecular Formula
- C22H28F2O5
- Formula Weight
- 410.45
- MOL File
- 209860-88-8.mol
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Property
- Boiling point:
- 575.9±50.0 °C(Predicted)
- Density
- 1.271±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DSMO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 3 mg/ml
- form
- Oil
- pka
- 4.76±0.10(Predicted)
- color
- Colorless to light yellow
- optical activity
- [α]/D 17 to 22°, c =1.0 in methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H360May damage fertility or the unborn child
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 10005439
- Product name
- Tafluprost (free acid)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 10005439
- Product name
- Tafluprost (free acid)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $509
- Updated
- 2024/03/01
- Product number
- 10005439
- Product name
- Tafluprost (free acid)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $904
- Updated
- 2024/03/01
- Product number
- 10005439
- Product name
- Tafluprost (free acid)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $1974
- Updated
- 2024/03/01
- Product number
- T004825
- Product name
- TafluprostAcid
- Packaging
- 25mg
- Price
- $1260
- Updated
- 2021/12/16
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Chemical Properties,Usage,Production
Uses
Tafluprost Acid is a derivative of Tafluprost (T004820), a novel prostanoid used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula.
Biological Activity
Taflupost acid is the active metabolite of Tafluprost, a prostaglandin F2α agonist th at lowers intraocular pressure and is used in the treatment of glaucoma. Taflupost acid has high affinity and selectivity for the prostaglandin PGF2α (FP) receptor with a Ki of 0.4 nM.
9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID manufacturers
- Product
- 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 209860-88-8
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-27
- Product
- 9ALPHA,11ALPHA-DIHYDROXY-15,15-DIFLUORO-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 209860-88-8
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-07-09