16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid

Product Name: 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
CAS No.: 465-18-9
Chemical Name: 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
Synonyms: Polyporenic acid C;Polyporenic acid C, 95%min;Polyporenic acid C, 10 mM in DMSO;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-dien-21-oic acid;3-Oxo-16α-hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid;cell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C;Lanosta-7,9(11)-dien-21-oic acid, 16-hydroxy-24-methylene-3-oxo-, (16α)-;16alpha-Hydroxy-24-methylene-3-oxo-5alpha-lanosta-7,9(11)-diene-30-oic acid;(2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
CBNumber: CB02274704
Molecular Formula: C31H46O4
Formula Weight: 482.69
MOL File: 465-18-9.mol

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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Property

Melting point:: 265-266℃
Boiling point:: 620.3±55.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 4.63±0.10(Predicted)
color: White to off-white
InChIKey: OWVUHYZGACFYHI-SUIRJFICNA-N
SMILES: C1(=O)C([C@@]2([H])[C@](C)(CC1)C1C([C@]3([C@@](CC=1)(C)[C@@H]([C@H](C)CCC(=C)C(C)C)[C@H](O)C3)C(O)=O)=CC2)(C)C |&1:3,5,11,12,16,17,26,r|
CAS DataBase Reference: 465-18-9

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 300817
Product name: Polyporenic acid C
Packaging: 5mg
Price: $623
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594398
Product name: Polyporenic acid C
Packaging: 5mg
Price: $591.6
Updated: 2021/12/16

AvaChem

Product number: 3288
Product name: Polyporenic acid C
Packaging: 20mg
Price: $1590
Updated: 2021/12/16

AvaChem

Product number: 3288
Product name: Polyporenic acid C
Packaging: 1mg
Price: $290
Updated: 2021/12/16

Arctom

Product number: CFN92739
Product name: PolyporenicacidC
Purity: ≥98%
Packaging: 5mg
Price: $338
Updated: 2021/12/16

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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Poria cocos.

Uses

Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].

Biological Activity

Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. It induces apoptosis through the death receptor-mediated apoptotic pathway without the involvement of mitochondria. It has the potential to be used in lung cancer research.

target

PARP | Caspase | PI3K | Akt | p53

References

[1] Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog.?2009 Jun;48(6):498-507. DOI:10.1002/mc.20487

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Suppliers

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View Lastest Price from 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Polyporenic acid C 465-18-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-22

Shanghai Standard Technology Co., Ltd.

Product: Polyporenic acid C 465-18-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥95%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-16

Career Henan Chemical Co

Product: 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid 465-18-9
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-10

465-18-9, 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acidRelated Search:

Raddeanin(Anemodeanin) A Ergosta-7,24(28)-dien-6-one,2,3,14,20,22-pentahydroxy-, (2b,3b,5b,22R)- Polyporusterone A HUMAN MDC (CCL22) DehydropachyMic acid PoMolic acid 28-O-beta-D-glucopyranosyl ester dehydrotumulosic acid 16α-Hydroxydehydrotrametenolic acid Pachymic acid 1→4-β-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B poricoic acid B 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 3-O-Acetyl-16alpha-hydroxytrametenolic acid Poricoic acid A(F) ARMEPAVINE Notoginsenoside Fa rubrofusarin gentiobioside VERBENALIN

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-dien-21-oic acid

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid

3-Oxo-16α-hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid

Polyporenic acid C

16alpha-Hydroxy-24-methylene-3-oxo-5alpha-lanosta-7,9(11)-diene-30-oic acid

Lanosta-7,9(11)-dien-21-oic acid, 16-hydroxy-24-methylene-3-oxo-, (16α)-

(2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid

cell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C

Polyporenic acid C, 10 mM in DMSO

Polyporenic acid C, 95%min

465-18-9

Triterpenoids