ChemicalBook > CAS DataBase List > 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
- Product Name
- 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
- CAS No.
- 465-18-9
- Chemical Name
- 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
- Synonyms
- Polyporenic acid C;Polyporenic acid C, 95%min;Polyporenic acid C, 10 mM in DMSO;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-dien-21-oic acid;3-Oxo-16α-hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid;cell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C;Lanosta-7,9(11)-dien-21-oic acid, 16-hydroxy-24-methylene-3-oxo-, (16α)-;16alpha-Hydroxy-24-methylene-3-oxo-5alpha-lanosta-7,9(11)-diene-30-oic acid;(2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
- CBNumber
- CB02274704
- Molecular Formula
- C31H46O4
- Formula Weight
- 482.69
- MOL File
- 465-18-9.mol
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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Property
- Melting point:
- 265-266℃
- Boiling point:
- 620.3±55.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.63±0.10(Predicted)
- color
- White to off-white
- InChIKey
- OWVUHYZGACFYHI-SUIRJFICNA-N
- SMILES
- C1(=O)C([C@@]2([H])[C@](C)(CC1)C1C([C@]3([C@@](CC=1)(C)[C@@H]([C@H](C)CCC(=C)C(C)C)[C@H](O)C3)C(O)=O)=CC2)(C)C |&1:3,5,11,12,16,17,26,r|
- CAS DataBase Reference
- 465-18-9
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N-Bromosuccinimide Price
Usbiological
- Product number
- 300817
- Product name
- Polyporenic acid C
- Packaging
- 5mg
- Price
- $623
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb594398
- Product name
- Polyporenic acid C
- Packaging
- 5mg
- Price
- $591.6
- Updated
- 2021/12/16
AvaChem
- Product number
- 3288
- Product name
- Polyporenic acid C
- Packaging
- 20mg
- Price
- $1590
- Updated
- 2021/12/16
AvaChem
- Product number
- 3288
- Product name
- Polyporenic acid C
- Packaging
- 1mg
- Price
- $290
- Updated
- 2021/12/16
Arctom
- Product number
- CFN92739
- Product name
- PolyporenicacidC
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $338
- Updated
- 2021/12/16
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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Poria cocos.
Uses
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].
Biological Activity
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. It induces apoptosis through the death receptor-mediated apoptotic pathway without the involvement of mitochondria. It has the potential to be used in lung cancer research.
target
PARP | Caspase | PI3K | Akt | p53
References
[1] Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog.?2009 Jun;48(6):498-507. DOI:10.1002/mc.20487
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Suppliers
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View Lastest Price from 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid manufacturers
Shaanxi Haibo Biotechnology Co., Ltd
- Product
- Polyporenic acid C 465-18-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-22
Shanghai Standard Technology Co., Ltd.
- Product
- Polyporenic acid C 465-18-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥95%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-16
Career Henan Chemical Co
- Product
- 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid 465-18-9
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-10
465-18-9, 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acidRelated Search:
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