2-Acetyl-3-phenylacrylic acid ethyl ester
- Product Name
- 2-Acetyl-3-phenylacrylic acid ethyl ester
- CAS No.
- 620-80-4
- Chemical Name
- 2-Acetyl-3-phenylacrylic acid ethyl ester
- Synonyms
- ETHYL ALPHA-ACETYLCINNAMATE;Ethyl2-benzylideneacetoacetate;ethyl 2-benzylidene-3-oxobutanoate;α-Benzylideneacetoacetic acid ethyl;α-Acetylbenzeneacrylic acid ethyl ester;2-Acetyl-3-phenylacrylic acid ethyl ester;2-Acetyl-3-phenylpropenoic acid ethyl ester;2-Benzylidene-3-oxobutyric acid ethyl ester;2-Benzylidene-3-oxobutanoic acid ethyl ester;ethyl (2Z)-3-oxo-2-(phenylMethylidene)butanoate
- CBNumber
- CB02285168
- Molecular Formula
- C13H14O3
- Formula Weight
- 218.25
- MOL File
- 620-80-4.mol
2-Acetyl-3-phenylacrylic acid ethyl ester Property
- Melting point:
- 60.5°C
- Boiling point:
- 296°C (estimate)
- Density
- 1.1367 (rough estimate)
- refractive index
- 1.5090 (estimate)
- FEMA
- 4597 | ETHYL ALPHA-ACETYLCINNAMATE
- storage temp.
- 2-8°C
- Odor
- at 100.00 %. balsamic aroma with tropical fruit notes
- Appearance
- Light yellow to yellow Solid
- Odor Type
- balsamic
- JECFA Number
- 4597
- LogP
- 2.21
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E1469
- Product name
- Ethyl 2-Benzylidene-3-oxobutanoate (mixture of isomers)
- Packaging
- 1G
- Price
- $186
- Updated
- 2025/07/31
- Product number
- CHM0311932
- Product name
- 3-OXO-2-(PHENYLMETHYLENE)BUTANOIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.54
- Updated
- 2021/12/16
- Product number
- CD12053109
- Product name
- Ethyl2-benzylidene-3-oxobutanoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $101
- Updated
- 2021/12/16
- Product number
- CM184977
- Product name
- ethyl(E)-2-benzylidene-3-oxobutanoate
- Purity
- 95%
- Packaging
- 5g
- Price
- $286
- Updated
- 2021/12/16
- Product number
- CD12053109
- Product name
- Ethyl2-benzylidene-3-oxobutanoate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $303
- Updated
- 2021/12/16
2-Acetyl-3-phenylacrylic acid ethyl ester Chemical Properties,Usage,Production
Synthesis
141-97-9
100-52-7
620-80-4
To an anhydrous DMSO solution containing L-proline (30 mol%) was added benzaldehyde (1 eq.). The reaction mixture was stirred at room temperature for 8-10 minutes, followed by the slow addition of ethyl acetoacetate (1.2 eq.) at the same temperature. The reaction system was warmed up to 80 °C with continuous stirring for 6-8 hours. Upon completion of the reaction, ethyl acetate (10 mL) was added to the mixture and stirred for several minutes before quenching the reaction with cold water. The organic and aqueous phases were separated and the aqueous phase was extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, washed with saturated saline and dried with anhydrous sodium sulfate. After concentration under reduced pressure to remove the solvent, the crude product was purified by column chromatography on silica gel (60-120 mesh), the eluent being a hexane solution of 5% ethyl acetate.
References
[1] Chemistry - A European Journal, 2017, vol. 23, # 21, p. 4962 - 4966
[2] Dalton Transactions, 2014, vol. 43, # 9, p. 3691 - 3697
[3] Journal of the Chemical Society, Perkin Transactions 1, 1980, p. 2645 - 2656
[4] Kinetics and Catalysis, 2011, vol. 52, # 4, p. 536 - 539
[5] Research on Chemical Intermediates, 2012, vol. 38, # 1, p. 25 - 35
2-Acetyl-3-phenylacrylic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
2-Acetyl-3-phenylacrylic acid ethyl ester Suppliers
- Tel
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- sales@carbosynth.com
- Country
- United Kingdom
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View Lastest Price from 2-Acetyl-3-phenylacrylic acid ethyl ester manufacturers
- Product
- 2-Acetyl-3-phenylacrylic acid ethyl ester 620-80-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2025-08-14