2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one

Product Name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
CAS No.: 20348-09-8
Chemical Name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Synonyms: Compound PDK0115;TIMTEC-BB SBB006815;LABOTEST-BB LT00451615;4H-pyrido[2,3-e][1,4]oxazin-3-one;4H-Pyrido[3,2-b][1,4]oxazin-3-one;2H,4H-pyrido[3,2-b][1,4]oxazin-3-one;2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE;2H-PYRIDO(3,2-B)-1,4-OXAZIN-3(4H)-ONE 95 %;2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine;3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-3-one
CBNumber: CB0229047
Molecular Formula: C7H6N2O2
Formula Weight: 150.13
MOL File: 20348-09-8.mol

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2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Property

Melting point:: 204-206 °C(lit.)
Boiling point:: 384.2±37.0 °C(Predicted)
Density: 1.327±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: liquid
pka: 11.06±0.20(Predicted)
Appearance: Off-white to light brown Solid
BRN: 1074010
InChI: 1S/C7H6N2O2/c10-6-4-11-5-2-1-3-8-7(5)9-6/h1-3H,4H2,(H,8,9,10)
InChIKey: ANHQLUBMNSSPBV-UHFFFAOYSA-N
SMILES: O=C1COc2cccnc2N1
CAS DataBase Reference: 20348-09-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 145246
Product name: 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one
Purity: 95%
Packaging: 5g
Price: $251.85
Updated: 2025/07/31

TRC

Product number: P991713
Product name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR9861
Product name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Purity: 95%
Packaging: 5g
Price: $42
Updated: 2021/12/16

Apolloscientific

Product number: OR9861
Product name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Purity: 95%
Packaging: 1g
Price: $12
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-1-36
Product name: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Purity: 95%
Packaging: 1g
Price: $20
Updated: 2021/12/16

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2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Chemical Properties,Usage,Production

Uses

2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one was used in the synthesis of quinazolinbenzoxazine derivatives.

Synthesis

16867-03-1

79-04-9

20348-09-8

A reaction mixture was prepared by mixing a solution of 2-amino-3-hydroxypyridine (45 mmol) and sodium bicarbonate (51 mmol) in water (30 mL) with 2-butanone (30 mL). A solution of 2-butanone (10 mL) with chloroacetyl chloride (51 mmol) was slowly added dropwise under ice-bath cooling conditions, and the rate of dropwise acceleration was controlled to keep the reaction temperature from exceeding 10°C. The reaction was carried out at room temperature. After dropwise addition, stirring was continued at room temperature for 30 min, and then the reaction was warmed up to 75°C for 1 hr. Upon completion of the reaction, the reaction solution was concentrated and purified by recrystallization (methanol/water=1:1) to afford 4.3 g of the target product 2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one.

References

[1] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 2, p. 133 - 142
[2] Helvetica Chimica Acta, 1976, vol. 59, p. 1593 - 1612
[3] Patent: CN103130792, 2016, B. Location in patent: Paragraph 0605-0607

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Suppliers

China 102 Germany 3 India 3 Switzerland 1 United Kingdom 6 United States 19 Global 134

J & K SCIENTIFIC LTD.

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Syntechem Co.,Ltd

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SuZhou ShiYa Biopharmaceuticals, Inc.

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View Lastest Price from 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one manufacturers

Shanghai Rlavie Technology Co ltd

Product: 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one 20348-09-8
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-09

Dideu Industries Group Limited

Product: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one 20348-09-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one 20348-09-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

20348-09-8, 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-oneRelated Search:

Metribuzin Buprofezin Copper Pyrithione Zinc pyrithione Piroctone olamine 7-CHLORO-2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)ONE 2-(2-HYDROXYETHYL)-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one 2-(3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-2-YL)ETHYL 4-CHLOROBENZENECARBOXYLATE BUTTPARK 26\07-94 2-[2-(4-ETHYLPIPERAZINO)ETHYL]-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2-(3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-2-YL)ETHYL 2-FUROATE 2-[2-(4-BENZYLPIPERAZINO)ETHYL]-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE BUTTPARK 26\07-97 2-(2-MORPHOLINOETHYL)-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2-(3-OXO-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-2-YL)ETHYL 4-FLUOROBENZENECARBOXYLATE BUTTPARK 26\07-100 BUTTPARK 26\07-91

LABOTEST-BB LT00451615

2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE

TIMTEC-BB SBB006815

2H-PYRIDO(3,2-B)-1,4-OXAZIN-3(4H)-ONE 95 %

4H-Pyrido[3,2-b][1,4]oxazin-3-one

3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-3-one

2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine

4H-pyrido[2,3-e][1,4]oxazin-3-one

2H,4H-pyrido[3,2-b][1,4]oxazin-3-one

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one ISO 9001：2015 REACH

Compound PDK0115

2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one

20348-09-8

Heterocyclic Building Blocks

Pyridines

C7 and C8

Building Blocks

C7 and C8

Heterocyclic Building Blocks

Pyridines

Heterocyclic Compounds

Pyridines, Pyrimidines, Purines and Pteredines