PP3

Product Name: PP3
CAS No.: 5334-30-5
Chemical Name: PP3
Synonyms: PP3;Amino d;NSC 1401;PP-3;PP 3;Inetetamab;PP 3, 10 mM in DMSO;PP3 ISO 9001：2015 REACH;PP3, Negative control for PP2;PP3 - CAS 5334-30-5 - Calbiochem;4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE
CBNumber: CB0230067
Molecular Formula: C11H9N5
Formula Weight: 211.22
MOL File: 5334-30-5.mol

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PP3 Property

Melting point:: 214-217 °C
storage temp.: -20°C
solubility: DMF, DMSO, Hot methanol
form: Off-white solid
color: Whit to Off-White
λmax: 240nm(H2O (pH 1))(lit.)
BRN: 198460
CAS DataBase Reference: 5334-30-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-22
Safety Statements: 36/37/39-26
Hazard Note: Irritant
HS Code: 29335995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2737
Product name: 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: A2737
Product name: 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $118
Updated: 2024/03/01

Alfa Aesar

Product number: L07125
Product name: 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
Packaging: 1g
Price: $62.1
Updated: 2021/12/16

Alfa Aesar

Product number: L07125
Product name: 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
Packaging: 5g
Price: $227
Updated: 2021/12/16

Cayman Chemical

Product number: 15595
Product name: PP3
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

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PP3 Chemical Properties,Usage,Production

Chemical Properties

Whit to Off-White Solid

Uses

Intermediate in the preparation of various enzymatic inhibitors

Uses

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]

Definition

ChEBI: 1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine is a ring assembly and a member of pyrazoles.

Biological Activity

Negative control for the src kinase inhibitor PP 2 (3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ). Inhibits EGFR kinase (IC 50 = 2.7 μ M).

storage

-20°C

PP3 Preparation Products And Raw materials

Raw materials

Preparation Products

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PP3 Suppliers

Americas 1 Belgium 1 Canada 1 China 49 Europe 1 Germany 2 India 4 Japan 3 United Kingdom 8 United States 22 USA 1 Global 93

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Acorn PharmaTech Co., Ltd.

Tel: 025-58395930
Fax: 025-5861-9182
Email: sales@acornpharma.com
Country: China
ProdList: 982
Advantage: 60

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

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View Lastest Price from PP3 manufacturers

Dideu Industries Group Limited

Product: PP3 5334-30-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-17

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 5334-30-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

5334-30-5, PP3Related Search:

PP3 1-PHENYLPYRAZOLE (1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YL)-HYDRAZINE NSC4912 BUTTPARK 59\40-21 BUTTPARK 56\40-48 BUTTPARK 127\40-10 BUTTPARK 141\40-58 BUTTPARK 141\40-57 BUTTPARK 127\40-15 4-[4-(4-METHYLPHENYL)PIPERAZIN-1-YL]-1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE BUTTPARK 127\40-02 BUTTPARK 127\40-12 BUTTPARK 127\40-09 BUTTPARK 127\40-07 BUTTPARK 127\40-11 BUTTPARK 127\40-08 BUTTPARK 126\40-99

4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE

4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE

4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE

1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE

PP3

1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine

4-Amino-1-phenylpyrazolo3,4-düpyrimidine, tech. 85%

4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE: TECH., 85%

4-Amino-1-phenylpyrazole[3,4-d]pyrimidine,95%

4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%

4-Amino-1-phenylpyrazolo[3,4-<i>d</i>]pyrimidine

NSC 1401

1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, tech

PP3 - CAS 5334-30-5 - Calbiochem

PP-3;PP 3

PP3 (4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine

Amino d

4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine &gt

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-phenyl-

PP3 ISO 9001：2015 REACH

ErbB-1,Epidermal growth factor receptor,PP3,inhibit,HER1,PP 3,EGFR,PP-3,Inhibitor

Inetetamab

PP3, Negative control for PP2

PP 3, 10 mM in DMSO

5334-30-5

AMINO

Intracellular Signaling

Amines

Aromatics

Heterocycles

Intermediates

Nucleotides and Nucleosides

Bases & Related Reagents

Nucleotides