PP3
- Product Name
- PP3
- CAS No.
- 5334-30-5
- Chemical Name
- PP3
- Synonyms
- PP3;Amino d;NSC 1401;PP-3;PP 3;Inetetamab;PP3 ISO 9001：2015 REACH;PP3 - CAS 5334-30-5 - Calbiochem;4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE
- CBNumber
- CB0230067
- Molecular Formula
- C11H9N5
- Formula Weight
- 211.22
- MOL File
- 5334-30-5.mol
PP3 Property
- Melting point:
- 214-217 °C
- storage temp.
- -20°C
- solubility
- DMF, DMSO, Hot methanol
- form
- Off-white solid
- color
- Whit to Off-White
- λmax
- 240nm(H2O (pH 1))(lit.)
- BRN
- 198460
- CAS DataBase Reference
- 5334-30-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-22
- Safety Statements
- 36/37/39-26
- Hazard Note
- Irritant
- HS Code
- 29335995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A2737
- Product name
- 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
- Purity
- >98.0%(HPLC)
- Packaging
- 200mg
- Price
- $38
- Updated
- 2024/03/01
- Product number
- A2737
- Product name
- 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $118
- Updated
- 2024/03/01
- Product number
- L07125
- Product name
- 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
- Packaging
- 1g
- Price
- $62.1
- Updated
- 2021/12/16
- Product number
- L07125
- Product name
- 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
- Packaging
- 5g
- Price
- $227
- Updated
- 2021/12/16
- Product number
- 15595
- Product name
- PP3
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
PP3 Chemical Properties,Usage,Production
Chemical Properties
Whit to Off-White Solid
Uses
Intermediate in the preparation of various enzymatic inhibitors
Uses
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]
Definition
ChEBI: 1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine is a ring assembly and a member of pyrazoles.
Biological Activity
Negative control for the src kinase inhibitor PP 2 (3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ). Inhibits EGFR kinase (IC 50 = 2.7 μ M).
storage
-20°C
PP3 Preparation Products And Raw materials
Raw materials
Preparation Products
PP3 Suppliers
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View Lastest Price from PP3 manufacturers
- Product
- PP3 5334-30-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-17
- Product
- 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 5334-30-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 4-AMino-1-phenylpyrazolo[3,4-D]pyriMidine 5334-30-5
- Price
- US $3265.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 2T
- Release date
- 2020-06-18