ChemicalBook > CAS DataBase List > PP3

PP3

Product Name
PP3
CAS No.
5334-30-5
Chemical Name
PP3
Synonyms
PP3;Amino d;NSC 1401;PP-3;PP 3;Inetetamab;PP3 ISO 9001：2015 REACH;PP3 - CAS 5334-30-5 - Calbiochem;4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE
CBNumber
CB0230067
Molecular Formula
C11H9N5
Formula Weight
211.22
MOL File
5334-30-5.mol
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PP3 Property

Melting point:
214-217 °C
storage temp. 
-20°C
solubility 
DMF, DMSO, Hot methanol
form 
Off-white solid
color 
Whit to Off-White
λmax
240nm(H2O (pH 1))(lit.)
BRN 
198460
CAS DataBase Reference
5334-30-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-22
Safety Statements 
36/37/39-26
Hazard Note 
Irritant
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2737
Product name
4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Purity
>98.0%(HPLC)
Packaging
200mg
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
A2737
Product name
4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Purity
>98.0%(HPLC)
Packaging
1g
Price
$118
Updated
2024/03/01
Alfa Aesar
Product number
L07125
Product name
4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
Packaging
1g
Price
$62.1
Updated
2021/12/16
Alfa Aesar
Product number
L07125
Product name
4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
Packaging
5g
Price
$227
Updated
2021/12/16
Cayman Chemical
Product number
15595
Product name
PP3
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
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PP3 Chemical Properties,Usage,Production

Chemical Properties

Whit to Off-White Solid

Uses

Intermediate in the preparation of various enzymatic inhibitors

Uses

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]

Definition

ChEBI: 1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine is a ring assembly and a member of pyrazoles.

Biological Activity

Negative control for the src kinase inhibitor PP 2 (3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ). Inhibits EGFR kinase (IC 50 = 2.7 μ M).

storage

-20°C

PP3 Preparation Products And Raw materials

Raw materials

Preparation Products

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PP3 Suppliers

Americas 1 Belgium 1 Canada 1 China 48 Europe 1 Germany 2 India 4 Japan 3 United Kingdom 8 United States 21 USA 1 Global 91
J & K SCIENTIFIC LTD.
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View Lastest Price from PP3 manufacturers

Dideu Industries Group Limited
Product
PP3 5334-30-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 5334-30-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Shaanxi Dideu Medichem Co. Ltd
Product
4-AMino-1-phenylpyrazolo[3,4-D]pyriMidine 5334-30-5
Price
US $3265.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
2T
Release date
2020-06-18

5334-30-5, PP3Related Search:

PP3 1-PHENYLPYRAZOLE (1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YL)-HYDRAZINE NSC4912 BUTTPARK 59\40-21 BUTTPARK 56\40-48 BUTTPARK 127\40-10 BUTTPARK 141\40-58 BUTTPARK 141\40-57 BUTTPARK 127\40-15 4-[4-(4-METHYLPHENYL)PIPERAZIN-1-YL]-1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE BUTTPARK 127\40-02 BUTTPARK 127\40-12 BUTTPARK 127\40-09 BUTTPARK 127\40-07 BUTTPARK 127\40-11 BUTTPARK 127\40-08 BUTTPARK 126\40-99

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  • 1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
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  • PP3 ISO 9001：2015 REACH
  • ErbB-1,Epidermal growth factor receptor,PP3,inhibit,HER1,PP 3,EGFR,PP-3,Inhibitor
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  • AMINO
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  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides