ChemicalBook > CAS DataBase List > 4,4'-THIODIANILINE

4,4'-THIODIANILINE

Product Name
4,4'-THIODIANILINE
CAS No.
139-65-1
Chemical Name
4,4'-THIODIANILINE
Synonyms
ASD;NCI-C01707;Thioaniline;4-Aminopheny;4-Aminophenylt;Arylsulfatase D;4,4'-Thioaniline;4,4’-thioaniline;4,4'-Thiodaniline;p,p-Thiodianiline
CBNumber
CB0230825
Molecular Formula
C12H12N2S
Formula Weight
216.3
MOL File
139-65-1.mol
More
Less

4,4'-THIODIANILINE Property

Melting point:
105-107 °C(lit.)
Boiling point:
361 °C
Density 
1.1391 (rough estimate)
refractive index 
1.5700 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
4.55±0.10(Predicted)
form 
neat
BRN 
1875513
InChIKey
ICNFHJVPAJKPHW-UHFFFAOYSA-N
CAS DataBase Reference
139-65-1(CAS DataBase Reference)
IARC
2B (Vol. 27, Sup 7) 1987
NIST Chemistry Reference
Benzenamine, 4,4'-thiobis-(139-65-1)
EPA Substance Registry System
4,4'-Thiodianiline (139-65-1)
More
Less

Safety

Hazard Codes 
T,N
Risk Statements 
45-22-51/53
Safety Statements 
53-45-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
BY9625000
8-10-21
HazardClass 
IRRITANT
PackingGroup 
III
HS Code 
29309090
Hazardous Substances Data
139-65-1(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H350May cause cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32955
Product name
4,4′-Diaminodiphenyl sulfide
Purity
analytical standard
Packaging
250mg
Price
$36
Updated
2021/12/16
Sigma-Aldrich
Product number
32955
Product name
4,4′-Diaminodiphenyl sulfide
Purity
analytical standard
Packaging
1g
Price
$103
Updated
2021/12/16
Sigma-Aldrich
Product number
436372
Product name
4,4′-Diaminodiphenyl sulfide
Purity
98%
Packaging
25g
Price
$218
Updated
2021/03/22
TCI Chemical
Product number
T0632
Product name
Bis(4-aminophenyl) Sulfide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$152
Updated
2021/12/16
TRC
Product number
T350330
Product name
4,4''-Thiodianiline
Packaging
5g
Price
$100
Updated
2021/12/16
More
Less

4,4'-THIODIANILINE Chemical Properties,Usage,Production

Chemical Properties

4,40-Thiodianiline is a brown-purple powder or needles.

Uses

4,4′-Thiodianiline was used almost exclusively as a chemical intermediate in the production of three dyes: C.I. mordant yellow 16, milling red G, and milling red FR. However, only mordant yellow 16 had any commercial significance in the United States (IARC 1982, HSDB 2009); it was used to dye wool and for printing on wool, silk, and cotton (SDC 1971). Mordant yellow 16 has been used as an indicator in the U.S. government’s nerve gas detector program (SOCMA 2002). However, no uses of either 4,4′-thiodianiline or mordant yellow 16 since the early 1990s have been reported.

Uses

4,4''-Thiodianiline is a carcinogenic aromatic amine used in the textile industry. It can also be used to modify electrodes in solar cells. Dyes and metabolites, Environmental Testing.

General Description

Needles or brown powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4,4'-THIODIANILINE is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. May generate heat with these materials and hydrogen gas or hydrogen sulfide gas. May liberate hydrogen sulfide if heated to decomposition or mixed with an acid. Also incompatible with peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 4,4'-THIODIANILINE emits very toxic fumes.

Fire Hazard

Flash point data for 4,4'-THIODIANILINE are not available, however 4,4'-THIODIANILINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also SULFIDES.

Potential Exposure

4,40-Thiodianiline is used as a dye intermediate; in organic sythesis; as a lab reagent. Antiplatyhelmintic agents; Carcinogens

Carcinogenicity

4,4′-Thiodianiline is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9Miscellaneous hazardous material, Technical Name Required. UN3143 dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

The free base is used for the detection of NO3 ions. The diacetate crystallises from aqueous AcOH with m 182o and the sulfoxide, m 184o, forms prisms from EtOH or H2O. [Fuson & Melamed J Org Chem 13 690 I1948, Beilstein 1 3 III 1246, 13, IV 1246.]

Incompatibilities

This material may be combustible. 4,40-Thiodianiline is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. May generate heat with these materials and hydrogen gas or hydrogen sulfide gas. May liberate hydrogen sulfide if heated to decomposition or mixed with an acid. Also incompatible with peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Light and moisture sensitive

Waste Disposal

It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

4,4'-THIODIANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4,4'-THIODIANILINE Suppliers

XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-2580635- ;0712-2580635
Email
1791901229@qq.com;1791901229@qq.com;
Country
China
ProdList
8924
Advantage
52
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-021-61259100
Fax
86-21-61259102
Email
int02@meryer.com
Country
China
ProdList
40264
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35909
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18227
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005;021-58099637-8009
Fax
021-58099609
Email
bin.wu@shlschem.com;sales@shlschem.com
Country
China
ProdList
9827
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
;021-54306202- ;
Fax
13764082696
Email
jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com
Country
China
ProdList
43059
Advantage
64
Chengdu XiYa Chemical Technology Co., Ltd.
Tel
;
Fax
0539-6365991
Email
sale@xiyashiji.com;3007716753@qq.com
Country
China
ProdList
10078
Advantage
57
Syntechem Co.,Ltd
Tel
Please Email
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
13009
Advantage
57
More
Less

View Lastest Price from 4,4'-THIODIANILINE manufacturers

Honest Joy Holdings Limited
Product
4,4'-Diaminodiphenyl sulfide, 139-65-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.3%
Supply Ability
100 tons
Release date
2022-01-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
4,4"-THIODIANILINE 139-65-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bis(4-aminophenyl) Sulfide 139-65-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

139-65-1, 4,4'-THIODIANILINERelated Search:


  • 4,4-diaminodiphenylsulphide
  • 4,4'-Thioaniline
  • 4,4'-Thiobis(aniline)
  • 4,4'-Thiobisbenzenamine
  • 4-[(4-Aminophenyl)sulfanyl]phenylamine
  • Aniline, 4,4'-thiodi-
  • Bis(4-aminophenyl)sulphide
  • Bis(p-aminophenyl)sulphide
  • bis(para-aminophenyl)sulphide
  • Di(p-aminophenyl)sulphide
  • di(para-aminophenyl)sulphide
  • diphenyl,4,4’-diamino-sulfid
  • NCI-C01707
  • p,p’-diaminodiphenylsulfide
  • 4,4'-DIAMINODIPHENYL SULFIDE
  • 4,4'-DI(AMINOPHENYL) SULFIDE
  • 4,4'-THIODIANILINE
  • 4-AMINOPHENYL SULFIDE
  • 4-AMINOPHENYLTHIOETHER
  • 2,2'-Thiobisbenzenamine
  • 4-[(4-aminophenyl)thio]aniline
  • (p-Aminophenyl)sulfide
  • 4,4'-Thiodianiline,95%
  • 4-Aminophenylthioether(4,4′-Thiodianiline)
  • 4-Aminophenyl Sulfide 4,4'-Thiodianiline
  • 4,4'-thiodianiline and its salts
  • 4-Aminopheny
  • 4,4'-Thiodaniline
  • 4,4′-Thiodianiline Solution, 100ppm
  • Anti-ARSD antibody produced in rabbit
  • Arylsulfatase D
  • Anti-Arylsulfatase D precursor antibody produced in rabbit
  • Anti-ASD antibody produced in rabbit
  • 4-Aminophenylt
  • 4,4’-diaminodiphenylsulphide
  • 4,4’-thioaniline
  • 4,4’-thiobis(aniline)
  • 4,4’-thiobis-benzenamin
  • 4,4’-thiobisbenzenamine
  • 4,4’-thiodi-anilin
  • 4,4-Diaminodiphenyl sulphide
  • 4,4'-Diaminodiphenylsulphide
  • p,p’-diaminodiphenylsulphide
  • p,p'-Diaminodiphenyl sulfide
  • p,p'-Diaminodiphenyl sulphide
  • p,p-Thiodianiline
  • para,para’-diaminodiphenylsulphide
  • para,para’-thiodianiline
  • Sulfide, bis(p-aminophenyl)
  • sulfide,bis(p-aminophenyl)
  • Thioaniline
  • Thiodi-p-phenylenediamine
  • BIS(P-AMINOPHENYL)SULFIDE
  • BIS(4-AMINOPHENYL) SULFIDE
  • ASD
  • DI(P-AMINOPHENYL)SULFIDE
  • 4-(4-aminophenylthio)benzenamine
  • 4,4-DIAMINODIPHENYL SULFIDE, STANDARDFOR GC