COELENTERAZINE HCP Property

Melting point:

>200℃

storage temp. 

-20°C

solubility 

Soluble in ethanol, methanol

form 

solid

color 

Yellow

λmax

433nm

Biological Applications

Calcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COELENTERAZINE HCP Chemical Properties,Usage,Production

Uses

Coelenterazine hcp has been used:

• as a component of coelenterazine reagent in the reporter assay
• in the purification of Renilla luciferase-labeled Annexin V
• in evaluating the activity of aequorin in Escherichia coli

General Description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.