Uses
ChemicalBook > CAS DataBase List > 2,6-Diaminopyridine

2,6-Diaminopyridine

Uses
Product Name
2,6-Diaminopyridine
CAS No.
141-86-6
Chemical Name
2,6-Diaminopyridine
Synonyms
2,6-DAP;Diaminopyridine;6-DiaMinopyridine;2,6-Pyridinediamine;pyridine-2,6-diyldiamine;26BD;NSC 403346;RODOL 26PYR;2.6-DiaMinopyr;2,6-Diaminopyridine
CBNumber
CB0236195
Molecular Formula
C5H7N3
Formula Weight
109.13
MOL File
141-86-6.mol
More
Less

2,6-Diaminopyridine Property

Melting point:
117-122 °C (lit.)
Boiling point:
285 °C (lit.)
Density 
1.7110 (rough estimate)
refractive index 
1.5340 (estimate)
Flash point:
155°C
storage temp. 
Store below +30°C.
solubility 
180g/l
pka
6.13±0.24(Predicted)
form 
Flakes or Crystalline Powder
color 
Beige to dark brown-gray
PH
>7 (H2O)
Water Solubility 
9.9 g/100 mL (20 ºC)
BRN 
108513
InChIKey
VHNQIURBCCNWDN-UHFFFAOYSA-N
LogP
0.550 (est)
CAS DataBase Reference
141-86-6(CAS DataBase Reference)
NIST Chemistry Reference
2,6-Pyridinediamine(141-86-6)
EPA Substance Registry System
2,6-Pyridinediamine (141-86-6)
More
Less

Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
22-36/37/38-25-20/21
Safety Statements 
26-45-37/39-28A-36
RIDADR 
2811
WGK Germany 
3
RTECS 
US7570000
F 
9
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D24404
Product name
2,6-Diaminopyridine
Purity
98%
Packaging
25g
Price
$51.5
Updated
2024/03/01
Sigma-Aldrich
Product number
D24404
Product name
2,6-Diaminopyridine
Purity
98%
Packaging
100g
Price
$129
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03575
Product name
2,6-Diaminopyridine
Purity
for synthesis
Packaging
100g
Price
$77.2
Updated
2024/03/01
TCI Chemical
Product number
D1154
Product name
2,6-Diaminopyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$30
Updated
2024/03/01
Alfa Aesar
Product number
A12295
Product name
2,6-Diaminopyridine, 98%
Packaging
100g
Price
$41.65
Updated
2024/03/01
More
Less

2,6-Diaminopyridine Chemical Properties,Usage,Production

Uses

2,6-Diaminopyridine(141-86-6) can be used to synthesize pentamidine derivatives which show antitumor activities and DNA binding activities. It can also be used to synthesize N-monocarbamoyl derivatives of symmetrical diamines with antiviral activity. Its derivatives can be used as models of molecular sensor for nucleic acid base detection.

Description

2,6-Diaminopyridine is an important organic reagent with a wide range of uses. It can be used for fluorescence detection, 2,6-Diaminopyridine fluorescence method for the determination of certain aromatic primary amines. It can also be used to prepare 2,6-Diaminopyridine imprinted core-shell nanoparticles. A new method for the detection of diaminopyridine derivatives using molecularly imprinted electrochemical sensors has been established, which has been applied to the detection of 2,6-Diaminopyridine in hair dyes with good sensitivity and selectivity.

Chemical Properties

Off-white crystal powder/granuale

Uses

2,6-Diaminopyridine, used as a pharmaceutical intermediate and a hair dye coupler in oxidation/permanent formulations.

Preparation

In a 600 mL autoclave equipped with a gas entrapment stirrer, a solution of 5 g CuI in 120 g aqueous ammonia (30% NH3 by weight) was added and mixed with 77 g ammonium acetate and 60 g of 2, 6-dichloropyridine. After purging with nitrogen, 24 g of liquid ammonia was added resulting in a pressure of about 150 psi (1.03 MPa). Subsequently, the reaction mixture was heated to 150°C for 8 h under stirring. Throughout the reaction, the pressure decreased from an initial pressure of 680 psi (4.69 MPa) to 450 psi (3.10 MPa). The reaction mixture was allowed to cool to room temperature, and the pressure was brought back to atmospheric pressure. Finally, 2,6-Diaminopyridine was obtained after purification.

Safety Profile

Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Toxicity evaluation

2,6-Diaminopyridine was not mutagenic in Salmonella typhimurium strain TA98 in the presence or absence of nonharman at 200 μg/plate. The mutagenicity of this compound was not enhanced by rodent liver S-9 (Sugimura et al., 1982).
In another study, it was not mutagenic in S. typhimurium strain TA98 without rodent liver S-9. However, it was mutagenic in the presence of rodent liver S-9 (Takahashi & Ono, 1993). 
This compound was not mutagenic in S. typhimurium strains TA98, TA100, and TA1535 in the presence or absence of rodent liver S-9 (JETOC, 1997; Takahashi & Ono, 1993)
It was mutagenic in S. typhimurium strain TA1537 in the presence or absence of rodent liver S-9 (JETOC, 1997).
2,6-Diaminopyridine was not mutagenic in Escherichia coli strain WP2 uvrA in the presence or absence of rodent liver S-9 (JETOC, 1997).

2,6-Diaminopyridine Preparation Products And Raw materials

Raw materials

2-Aminopyridine

Preparation Products

7-FLUORO-[1,8]NAPHTHYRIDIN-2-OL 2,6-DIAMINO-3-BROMOPYRIDINE Minoxidil 3-Bromo-2,6-diaminopyridine ,95%
More
Less

2,6-Diaminopyridine Suppliers

Americas 1 Belgium 3 Canada 4 China 427 Czech Republic 1 Europe 4 France 1 Germany 5 India 59 Japan 5 Jordan 1 Slovakia 1 South Korea 2 Switzerland 3 Ukraine 1 United Kingdom 14 United States 44 Global 576
Hubei Wande Chemical Co., Ltd
Tel
027-59210159 15377098680
Fax
027-59210159
Email
1148280011@qq.com
Country
China
ProdList
9978
Advantage
58
Macheng jinxin biotechnology co., LTD
Tel
18271582018
Email
1126319697@qq.com
Country
China
ProdList
1534
Advantage
58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82375886 13001715031
Fax
0531-82375893
Email
3517280075@qq.com
Country
China
ProdList
1205
Advantage
58
Changsha Changtang Import and Export Co., LTD
Tel
15388971408 15388971408
Fax
0731-84372366
Email
1121549170@qq.com
Country
China
ProdList
1003
Advantage
58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd
Tel
18072846723
Email
caigou1@witofly.com
Country
China
ProdList
18924
Advantage
58
Wuxi KaiLi Biotech Co.,Ltd
Tel
0510-80721533 13327925606
Email
sales@klbiotech.com
Country
China
ProdList
127
Advantage
58
Hubei DAHAO Chemical Co., Ltd.
Tel
027-59106191 13986034860
Email
1400828855@qq.com
Country
China
ProdList
9964
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94837
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2882
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9492
Advantage
66
Winchem Industrial Co. Ltd
Tel
0574-83851061
Fax
86-574-87083209
Email
info@win-chemical.com
Country
China
ProdList
500
Advantage
55
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18086
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3205
Advantage
55
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.
Tel
0523-82837785 13365232216
Fax
0523-87913272
Email
info@jszchg.com
Country
China
ProdList
245
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9352
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4171
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1975
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
More
Less

View Lastest Price from 2,6-Diaminopyridine manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
2,6-Diaminopyridine 141-86-6
Price
US $68.40/Kg/Drum
Min. Order
5Kg/Drum
Purity
99.00%HPLC
Supply Ability
6tons/month
Release date
2021-11-09
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2, 6-Diaminopyridine 141-86-6
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-06
Hebei Guanlang Biotechnology Co., Ltd.
Product
2,6-Diaminopyridine 141-86-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-11-11

141-86-6, 2,6-DiaminopyridineRelated Search:

2-Aminopyridine 3-Aminopyridine DIMETHYLAMINOPYRIDINE, POLYMER-BOUND 4-Aminopyridine 4-Dimethylaminopyridine 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE 2,6-DIAMINO-3-NITROSOPYRIDINE Phenazopyridine hydrochloride 2,6-DIACETYLAMINOPYRIDINE 2,5-DIAMINOPYRIDINE 2,3-DIAMINOPYRIDINE,2,3-Diaminopyridine,98%,2,3-Diaminopyridine99% 2,6-DIAMINO-4-METHYL PYRIDINE Enoxacin 2,4-DIAMINOPYRIDINE 3,4-DIAMINOPYRIDINE,DIAMINOPYRIDINE(3,4-),4,5-diaminopyridin 2,3-Diamino-6-methoxypyridine 4-Chloro-2,6-diaminopyridine PYRIDINE-2,3,6-TRIAMINE

  • 2,6-diamino-pyridin
  • Diaminopyridine
  • Pyridine, 2,6-diamino-
  • pyridine-2,6-diyldiamine
  • 2 6-DIAMINOPYRIDINE 99+% &
  • 2,6-Diaminopyridine,>98%
  • D**2,6-Diaminopyridine
  • 2,6-DAP
  • 2,6-Diaminopyridine
  • 2,6-Pyridinediamine
  • RODOL 26PYR
  • 6-Amino-2(1H)-pyridinimine
  • 2.6-Diaminopyridine 10g [141-86-6]
  • 6-DiaMinopyridine
  • 2,6-DiaMinopyridine, 98% 100GR
  • NSC 403346
  • Pyridine, 2,6-diaMino- (6CI,8CI)
  • 2, 6-2 aMinopyridine
  • 2.6-DiaMinopyr
  • 2,6-Diaminopyridine Vetec(TM) reagent grade, 98%
  • 2,6-DIAMINOPYRIDINE FOR SYNTHESIS
  • 2,6-DAP 2,6-DiaMinopyridine
  • 2,6-Diaminopyridine ( CAS : 141-86-6)
  • 2,6-Diaminopyridine@100 μg/mL in Methanol
  • Diaminopyridine Diaminopyridine
  • 2,6-Diaminopyridine, 98%, for synthesis
  • 2,6-Diaminopyridine &gt
  • 2,6-diamino-pyridine(2.6BD)
  • 26BD
  • 2,6-Diaminopyridine ISO 9001：2015 REACH
  • 2,6-Diaminopyridine?New
  • Dopexamine Impurity 16
  • 141-86-6
  • C5H9N3O4S
  • AMINE
  • C5
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyridines
  • Pyridine
  • C5
  • Heterocyclic Building Blocks
  • Pyridines
  • Pyridines derivates
  • compounds of pyridine
  • Intermediates