ANTI-MDM2
- Product Name
- ANTI-MDM2
- Chemical Name
- ANTI-MDM2
- Synonyms
- HDMX;MDMX;HDM2;LSKB;ACTFS;MGC5370;MGC71221;ANTI-MDM4;ANTI-HDMX;ANTI-MDM2
- CBNumber
- CB0241012
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-MDM2 Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SAB4501852
- Product name
- Anti-MDM4 antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $522
- Updated
- 2025/07/31
- Product number
- SAB4501849
- Product name
- Anti-MDM2 antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μG
- Price
- $522
- Updated
- 2025/07/31
- Product number
- SAB4300601
- Product name
- Anti-MDM2 (Ab-166) antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $455
- Updated
- 2025/07/31
- Product number
- SAB2500625
- Product name
- Anti-MDM2 (Isoform) antibody produced in goat
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 100μg
- Price
- $586
- Updated
- 2025/07/31
- Product number
- HPA048821
- Product name
- Anti-MDM4 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
- Packaging
- 100μL
- Price
- $555
- Updated
- 2025/07/31
ANTI-MDM2 Chemical Properties,Usage,Production
Uses
Monoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX).
General Description
Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.
Biochem/physiol Actions
MDMX is a structural homolog of MDM2 and inhibits the tumor suppressor, p53. MDMX also prevents MDM2-mediated degradation of p53, and subsequently regulates cellular levels of p53. MDMX also modulates cell growth and survival. Thus, MDMX can be useful as a therapeutic target in cancers, especially in tumors where native p53 functions can be restored . Monoclonal Anti-MDMX antibody is specific for human MDMX.
ANTI-MDM2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MDM2 Suppliers
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