(6-BROMO-PYRIDIN-3-YL)-METHANOL

Product Name: (6-BROMO-PYRIDIN-3-YL)-METHANOL
CAS No.: 122306-01-8
Chemical Name: (6-BROMO-PYRIDIN-3-YL)-METHANOL
Synonyms: CAS:122306-01-8;2-Bromopyridine-5-methanol;6-Bromo-3-pyridinemethanol;6-BroMopyridine-3-Methanol;(6-BroMo-3-pyridyl)Methanol;3-Pyridinemethanol, 6-bromo-;6-Bromo-3-pyridinemethanol >2-BroMo-5-pyridineMethanol, 95%;(6-BROMO-PYRIDIN-3-YL)-METHANOL;(2-BROMO-PYRIDIN-5-YL)-METHANOL
CBNumber: CB0243243
Molecular Formula: C6H6BrNO
Formula Weight: 188.02
MOL File: 122306-01-8.mol

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(6-BROMO-PYRIDIN-3-YL)-METHANOL Property

Melting point:: 48-51℃
Boiling point:: 314.3±27.0 °C(Predicted)
Density: 1.668±0.06 g/cm3(Predicted)
Flash point:: >110℃
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 13.29±0.10(Predicted)
color: White to Light yellow to Light orange
InChIKey: QPPDKOIDAYZUHN-UHFFFAOYSA-N
CAS DataBase Reference: 122306-01-8

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 762539
Product name: 6-Bromopyridine-3-methanol
Purity: 97%
Packaging: 1g
Price: $49.1
Updated: 2023/06/20

TCI Chemical

Product number: B3494
Product name: 6-Bromo-3-pyridinemethanol
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $98
Updated: 2025/07/31

TCI Chemical

Product number: B3494
Product name: 6-Bromo-3-pyridinemethanol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $391
Updated: 2025/07/31

TRC

Product number: B688843
Product name: (6-Bromo-pyridin-3-yl)methanol
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: B10364
Product name: 2-Bromo-5-(hydroxymethyl)pyridine
Purity: 98%
Packaging: 1g
Price: $8
Updated: 2021/12/16

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(6-BROMO-PYRIDIN-3-YL)-METHANOL Chemical Properties,Usage,Production

Uses

2-Bromo-5-pyridinemethanol is used as a pharmaceutical intermediate.

Synthesis

149806-06-4

122306-01-8

General procedure for the synthesis of 2-bromo-5-(hydroxymethyl)pyridine from 2-bromo-5-formylpyridine: Sodium borohydride (4.88 g, 0.026 mol) was added batchwise to a solution of 6-bromonicotinaldehyde (20.0 g, 0.11 mol) in methanol (108 mL) at 20-30 °C. The reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction mixture was diluted with saturated aqueous ammonium chloride solution. The mixture was concentrated to remove methanol and the resulting aqueous solution was extracted with ethyl acetate. The organic phase was washed sequentially with saturated aqueous sodium bicarbonate and brine, dried over magnesium sulfate, filtered and concentrated to afford 2-bromo-5-(hydroxymethyl)pyridine (18.61 g, 92% yield) as a light yellow solid.1H-NMR (300 MHz, CDCl3) δ (ppm): 8.36 (d, J = 2.7Hz, 1H), 7.60 (dd, J = 8.1, 2.7Hz, 1H). 2.7 Hz, 1H), 7.49 (d, J = 8.1 Hz, 1H), 4.72 (s, 2H), 1.95 (s, 1H).

References

[1] Patent: WO2013/44360, 2013, A1. Location in patent: Paragraph 000299-000300
[2] Patent: WO2006/114213, 2006, A1. Location in patent: Page/Page column 29-30
[3] Patent: WO2012/177603, 2012, A2. Location in patent: Page/Page column 105-108
[4] Journal of Organic Chemistry, 2004, vol. 69, # 2, p. 250 - 262
[5] Dalton Transactions, 2012, vol. 41, # 3, p. 1074 - 1081

(6-BROMO-PYRIDIN-3-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(6-BROMO-PYRIDIN-3-YL)-METHANOL Suppliers

Americas 1 China 159 Europe 1 India 3 Japan 1 Switzerland 2 United Kingdom 2 United States 19 Global 188

J & K SCIENTIFIC LTD.

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View Lastest Price from (6-BROMO-PYRIDIN-3-YL)-METHANOL manufacturers

Henan Fengda Chemical Co., Ltd

Product: (6-BROMO-PYRIDIN-3-YL)-METHANOL 122306-01-8
Price: US $3.00-0.20/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-26

Dideu Industries Group Limited

Product: (6-BROMO-PYRIDIN-3-YL)-METHANOL 122306-01-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-25

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-Bromo-3-pyridinemethanol 122306-01-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

122306-01-8, (6-BROMO-PYRIDIN-3-YL)-METHANOLRelated Search:

Ethyl 6-bromopicolinate 6-Bromonicotinic acid 5,6-DIBROMOPYRIDINE-3-CARBOXYLIC ACID (6-BROMO-PYRIDIN-3-YL)-METHANOL t-butyl 6-bromo-3-pyridinecarboxylate ETHYL 6-BROMOPYRIDINE-3-CARBOXYLATE Methyl 6-bromonicotinate (6-BROMO-PYRIDIN-2-YL)-METHANOL,(6-Bromo-pyridin-2-yl)-methanol >97% (2-BROMO-PYRIDIN-4-YL)-METHANOL 5-Bromo-2-hydroxymethylpyridine (2-AMINO-5-BROMO-PYRIDIN-3-YL)-METHANOL (5-BROMO-PYRIDIN-3-YL)-METHANOL (2-BROMO-PYRIDIN-3-YL)-METHANOL 2-BROMO-3-METHYLPYRIDINE-5-CARBOXYLIC ACID 6-BROMO-5-FLUOROPYRIDINE-3-CARBOXYLIC ACID ethyl 6-bromonicotinimidate (6-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL

2-Bromo-5-(hydroxymethyl)pyridine

6-Bromo-3-pyridinemethanol

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(2-BROMO-PYRIDIN-5-YL)-METHANOL

(6-BROMO-PYRIDIN-3-YL)-METHANOL

6-BroMopyridine-3-Methanol

2-BroMo-5-pyridineMethanol, 95%

(6-BroMo-3-pyridyl)Methanol

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(6-BROMO-PYRIDIN-3-YL)-METHANOL ISO 9001：2015 REACH

CAS:122306-01-8

122306-01-8

Building Blocks

Pyridine