ZONIPORIDE

Product Name
ZONIPORIDE
CAS No.
241800-98-6
Chemical Name
ZONIPORIDE
Synonyms
CP 597396;ZONIPORIDE;Zoniporide hydrochloride hydrate;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
CBNumber
CB02448312
Molecular Formula
C17H16N6O
Formula Weight
320.35
MOL File
241800-98-6.mol
More
Less

ZONIPORIDE Property

Density 
1.54
storage temp. 
2-8°C
solubility 
H2O: soluble2mg/mL, clear (warmed)
form 
powder
pka
11.44±0.46(Predicted)
color 
white to tan
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0076
Product name
Zoniporide hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
10mg
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0076
Product name
Zoniporide hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
50mg
Price
$966
Updated
2024/03/01
More
Less

ZONIPORIDE Chemical Properties,Usage,Production

Uses

Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.

Biochem/physiol Actions

Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.

ZONIPORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ZONIPORIDE Suppliers

China 7 The Netherlands 1 United Kingdom 1 United States 1 USA 1 Global 11
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49391
Advantage
58
Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
ProdList
20035
Advantage
58
Jinan Sanbao Biotechnology Co., Ltd.
Tel
13854185395; 13854185395
Email
sanbaobiotech@126.com
Country
China
ProdList
9375
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
sun_dan@PharmaBlock.com
Country
China
ProdList
7268
Advantage
58
Shaoyuan Technology (Shanghai) Co., Ltd.
Tel
021-50795510 4000665055
Email
sy-c6@accelachem.com
Country
China
ProdList
10129
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323967 +86-18015559028
Email
sales1@artkmedchem.com
Country
China
ProdList
39009
Advantage
58

241800-98-6, ZONIPORIDERelated Search:

5-ISOPROPYL-1-PHENYL-1H-PYRAZOLE ZONIPORIDE 5-METHYL-1-PHENYL-(1H-PYRAZOL-4-YLMETHYL)AMINE HYDROCHLORIDE

  • N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine
  • CP 597396
  • ZONIPORIDE
  • N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
  • Zoniporide hydrochloride hydrate
  • 1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-
  • N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide
  • 241800-98-6