ZONIPORIDE
- Product Name
- ZONIPORIDE
- CAS No.
- 241800-98-6
- Chemical Name
- ZONIPORIDE
- Synonyms
- CP 597396;ZONIPORIDE;Zoniporide hydrochloride hydrate;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
- CBNumber
- CB02448312
- Molecular Formula
- C17H16N6O
- Formula Weight
- 320.35
- MOL File
- 241800-98-6.mol
ZONIPORIDE Property
- Density
- 1.54
- storage temp.
- 2-8°C
- solubility
- H2O: soluble2mg/mL, clear (warmed)
- form
- powder
- pka
- 11.44±0.46(Predicted)
- color
- white to tan
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML0076
- Product name
- Zoniporide hydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $242
- Updated
- 2024/03/01
- Product number
- SML0076
- Product name
- Zoniporide hydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $966
- Updated
- 2024/03/01
ZONIPORIDE Chemical Properties,Usage,Production
Uses
Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.
Biochem/physiol Actions
Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.
ZONIPORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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