ZONIPORIDE

Product Name: ZONIPORIDE
CAS No.: 241800-98-6
Chemical Name: ZONIPORIDE
Synonyms: CP 597396;ZONIPORIDE;Zoniporide hydrochloride hydrate;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
CBNumber: CB02448312
Molecular Formula: C17H16N6O
Formula Weight: 320.35
MOL File: 241800-98-6.mol

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ZONIPORIDE Property

Density: 1.54
storage temp.: 2-8°C
solubility: H2O: soluble2mg/mL, clear (warmed)
form: powder
pka: 11.44±0.46(Predicted)
color: white to tan
Water Solubility: H2O: 2mg/mL, clear (warmed)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0076
Product name: Zoniporide hydrochloride hydrate
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $247.95
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0076
Product name: Zoniporide hydrochloride hydrate
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $993
Updated: 2025/07/31

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ZONIPORIDE Chemical Properties,Usage,Production

Uses

Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.

Biochem/physiol Actions

Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.

ZONIPORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ZONIPORIDE Suppliers

China 22 The Netherlands 1 United Kingdom 1 United States 2 USA 1 Global 27

Sigma-Aldrich

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241800-98-6, ZONIPORIDERelated Search:

5-ISOPROPYL-1-PHENYL-1H-PYRAZOLE ZONIPORIDE 5-METHYL-1-PHENYL-(1H-PYRAZOL-4-YLMETHYL)AMINE HYDROCHLORIDE

N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine

CP 597396

ZONIPORIDE

N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate

Zoniporide hydrochloride hydrate

1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-

N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide

241800-98-6