ChemicalBook > CAS DataBase List > 4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE

4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE

Product Name
4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE
CAS No.
34334-28-6
Chemical Name
4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE
Synonyms
AKOS B030325;4-(4-METHYLPIPERAZINO)BENZONITRILE;4-(Methyl-piperazin-1-yl)benzonitrile;4-(4-Methyl-1-piperazinyl)benzonitrile;4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE;Benzonitrile, 4-(4-methyl-1-piperazinyl)-
CBNumber
CB0244992
Molecular Formula
C12H15N3
Formula Weight
201.27
MOL File
34334-28-6.mol
More
Less

4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE Property

Melting point:
104-105℃
Boiling point:
356.5±37.0 °C(Predicted)
Density 
1.14
storage temp. 
Sealed in dry,Room Temperature
pka
7.62±0.42(Predicted)
Appearance
White to light yellow Solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-B1832
Product name
Benzonitrile,4-(4-methyl-1-piperazinyl)-
Packaging
5g
Price
$113
Updated
2021/12/16
AK Scientific
Product number
4116AB
Product name
4-(4-Methylpiperazin-1-yl)benzonitrile
Packaging
10g
Price
$265
Updated
2021/12/16
AK Scientific
Product number
4116AB
Product name
4-(4-Methylpiperazin-1-yl)benzonitrile
Packaging
5g
Price
$169
Updated
2021/12/16
ChemScene
Product number
CS-B1832
Product name
Benzonitrile,4-(4-methyl-1-piperazinyl)-
Packaging
10g
Price
$187
Updated
2021/12/16
ChemScene
Product number
CS-B1832
Product name
Benzonitrile,4-(4-methyl-1-piperazinyl)-
Packaging
25g
Price
$374
Updated
2021/12/16
More
Less

4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE Chemical Properties,Usage,Production

Synthesis

109-01-3

1194-02-1

34334-28-6

The general procedure for the synthesis of 4-(4-methylpiperazin-1-yl)benzonitrile from N-methylpiperazine and p-fluorobenzonitrile was as follows: to a solution of dimethyl sulfoxide (7 mL) containing 4-fluorobenzonitrile (1.0 g, 8.25 mmol) and potassium carbonate (2.27 g, 16.51 mmol) was added 1-methylpiperazine (1.36 mL, 12.38 mmol). The reaction mixture was stirred at room temperature for the reaction. Upon completion of the reaction, the target product 4-(4-methylpiperazin-1-yl)benzonitrile (1.54 g, 93% yield) was obtained by conventional post-processing. The structure of the product was confirmed by 1H-NMR (500 MHz, CDCl3) and ESI-MS: 1H-NMR δ 2.36 (3H, s), 2.55 (4H, t, J = 4.88 Hz), 3.35 (4H, t, J = 4.88 Hz), 6.87 (2H, d, J = 8.78 Hz), 7.49 (2H, d, J = 8.78 Hz); ESI-MS m/z 202.1 ([M+H]+).

References

[1] Journal of Medicinal Chemistry, 2005, vol. 48, # 26, p. 8261 - 8269
[2] Patent: WO2005/7625, 2005, A2. Location in patent: Page 63
[3] Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 5, p. 1252 - 1263
[4] Patent: WO2016/96709, 2016, A1. Location in patent: Page/Page column 50
[5] Patent: US2008/146542, 2008, A1. Location in patent: Page/Page column 36

4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE Suppliers

China 61 Germany 1 India 2 The Netherlands 1 Ukraine 1 United Kingdom 3 United States 6 Global 75
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from 4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE manufacturers

Career Henan Chemical Co
Product
4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE 34334-28-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Judy@coreychem.com
Release date
2019-12-18

34334-28-6, 4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILERelated Search:

4-[4-(4-CHLOROBENZOYL)PIPERAZINO]BENZENECARBONITRILE N-(4-CHLOROPHENYL)-4-(4-CYANOPHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE 4-[4-(4-METHOXYBENZOYL)PIPERAZINO]BENZENECARBONITRILE 4-[4-(3-CHLOROBENZOYL)PIPERAZINO]BENZENECARBONITRILE 4-(4-benzylpiperazin-1-yl)benzonitrile 4-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)BENZENECARBONITRILE 4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE Benzonitrile, 4-[4-[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]-1-piperazinyl]- N-(3-CHLOROPHENYL)-4-(4-CYANOPHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE 4-(4-[3-(TRIFLUOROMETHYL)BENZOYL]PIPERAZINO)BENZENECARBONITRILE 4-[4-(3-METHOXYBENZOYL)PIPERAZINO]BENZENECARBONITRILE 4-[4-(4-FLUOROBENZOYL)PIPERAZINO]BENZENECARBONITRILE 4-(4-[4-(TRIFLUOROMETHYL)BENZOYL]PIPERAZINO)BENZENECARBONITRILE 4-[4-(4-AMINOBENZOYL)PIPERAZINO]BENZENECARBONITRILE 4-[4-(2-THIENYLCARBONYL)PIPERAZINO]BENZENECARBONITRILE TERT-BUTYL 4-(4-CYANOPHENYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE

  • 4-(4-METHYL-PIPERAZIN-1-YL)BENZONITRILE
  • 4-(4-METHYLPIPERAZINO)BENZONITRILE
  • AKOS B030325
  • 4-(Methyl-piperazin-1-yl)benzonitrile
  • 4-(4-Methyl-1-piperazinyl)benzonitrile
  • Benzonitrile, 4-(4-methyl-1-piperazinyl)-
  • 34334-28-6