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BROMAMPHENICOL

Product Name
BROMAMPHENICOL
CAS No.
16803-75-1
Chemical Name
BROMAMPHENICOL
Synonyms
Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
CBNumber
CB02451280
Molecular Formula
C11H12Br2N2O5
Formula Weight
412.03
MOL File
16803-75-1.mol
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BROMAMPHENICOL Property

Melting point:
155-156 °C
Boiling point:
664.4±55.0 °C(Predicted)
Density 
1.939±0.06 g/cm3(Predicted)
pka
11.14±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B679578
Product name
Bromamphenicol
Packaging
10mg
Price
$120
Updated
2021/12/16
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BROMAMPHENICOL Chemical Properties,Usage,Production

Uses

Bromamphenicol is a semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide, first reported in 1950. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.

Uses

Bromamphenicol is a semi-synthetic chloramphenicol analogue first reported in 1950, in which the dichloroacetamide is replaced with dibromoacetamide. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.

BROMAMPHENICOL Preparation Products And Raw materials

Raw materials

Preparation Products

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16803-75-1, BROMAMPHENICOLRelated Search:


  • Acetamide, 2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
  • 16803-75-1
  • C11H12Br2N2O5