D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

Product Name: D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
CAS No.: 716-61-0
Chemical Name: D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
Synonyms: (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL;ChloromycinbaseL-base;levoamine;Chloromycin base;L-BASE (AMINODIOL);chloramphenicolbase;D(-)Threo-1-(4-nitro;Chloramphenicol impurity D;Chloramphenicol Impurity 1;Chloramphenicol Impurity A
CBNumber: CB6452870
Molecular Formula: C9H12N2O4
Formula Weight: 212.2
MOL File: 716-61-0.mol

More

Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Property

Melting point:: 163-165 °C(lit.)
Boiling point:: 352.03°C (rough estimate)
Density: 1.3136 (rough estimate)
refractive index: -30.5 ° (C=1, 6mol/L HCl)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Water Solubility: almost transparency in hot Water
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.98±0.45(Predicted)
form: Powder
color: Light yellow
optical activity: [α]25/D 30°, c = 1 in 6 M HCl
InChIKey: OCYJXSUPZMNXEN-RKDXNWHRSA-N

More

Less

Safety

Hazard Codes: Xn,T
Risk Statements: 22-36/37/38-45
Safety Statements: 26-45-53-22
RIDADR: UN 3259 8/PG 3
WGK Germany: 3
RTECS: TY3100000
HS Code: 29221990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A70704
Product name: (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity: 99%
Packaging: 10g
Price: $107
Updated: 2024/03/01

Sigma-Aldrich

Product number: A70704
Product name: (1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity: 99%
Packaging: 25g
Price: $146
Updated: 2024/03/01

TCI Chemical

Product number: A1017
Product name: D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity: >98.0%(T)
Packaging: 25g
Price: $79
Updated: 2024/03/01

TCI Chemical

Product number: A1017
Product name: D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity: >98.0%(T)
Packaging: 500g
Price: $689
Updated: 2024/03/01

TRC

Product number: A622680
Product name: D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Packaging: 50g
Price: $240
Updated: 2021/12/16

More

Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

Uses

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].

Uses

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.

Definition

ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Preparation Products And Raw materials

Raw materials

Propiophenone

Preparation Products

Potassium heptadecafluoro-1-octanesulfonate

More

Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Suppliers

Americas 1 Belgium 1 Canada 1 China 169 Europe 4 Germany 3 India 7 Japan 2 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 10 United States 23 Global 224

Ningbo Enzyme Chemical Co., LTD

Tel: 0574-87730716-654 13819816642
Email: chngsi.liu@enzymaster.com
Country: China
ProdList: 37
Advantage: 58

Yancheng Huahong Chemical Co., Ltd.

Tel: 15366451979
Email: sales@huahongchem.com
Country: China
ProdList: 23
Advantage: 58

Ningbo biermann pharmaceutical technology co., LTD

Tel: 0571-82572971 13736400971
Fax: 0574-87703432
Email: bichem.sales01@bichem.cn
Country: China
ProdList: 47
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12458
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

More

Less

View Lastest Price from D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL manufacturers

Hebei Duling International Trade Co. LTD

Product: D(-)Threo-1-(4-nitrophenyl)-2-amino-1,3-propanediol 716-61-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000tons
Release date: 2022-10-13

Hebei Yanxi Chemical Co., Ltd.

Product: ChloromycinbaseL-base 716-61-0
Price: US $10.00-3.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 15 tons
Release date: 2023-09-27

Hebei Guanlang Biotechnology Co., Ltd.

Product: ChloromycinbaseL-base 716-61-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-10-09

716-61-0, D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOLRelated Search:

Chloramphenicol palmitate D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chloramphenicol sodium succinate Eusynthomycin Chloramphenicol (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol 2-Amino-1,3-propanediol Nitrophenol 2-Amino-1-(4-nitrophenyl)-1,3-propanediol CHLORAMPHENICOL 1-O-BETA-D-GALACTOPYRANOSIDE (1R,2R)-B13 BROMAMPHENICOL CHLORAMPHENICOL (D5) CHLORAMPHENICOL-ALCOHOL L-(+)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL BOC-(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL FMOC-(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL D-THREO-[DICHLOROACETYL-1-14C]-CHLORAMPHENICOL

ChloromycinbaseL-base

D-(-)-THREO-2-AMINO-1-(4-NITRO

(1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol

[1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol

(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96%

(1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base

(1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR

(1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99%

(1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96%

(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride

L-BASE (AMINODIOL)

<small>D</small>-(-)-<i>threo</i>-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay)

d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol

levoamine

Chloromycin base

2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)-

chloramphenicolbase

Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyL

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL

CHLORAMPHENICOL-WATER SOLUBLE

(1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL

(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

(1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL

CHLORAMPHENICOL BASE CRYSTALLINE

(1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99%

D(-)Threo-1-(4-nitro-phenyl)-2

1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)-

D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE

(1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL

D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol

(R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol

(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol nitrate

Chloramphenicol impurity D

(D)-(-)-threo-2-Amino-1-(4-nitrophe

Chloramphenicol Impurity 1 (D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol)

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol &gt

Chloramphenicol Impurity 1

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL USP/EP/BP

D(-)Threo-1-(4-nitro

(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-aminium

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol/D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

Chloramphenicol Impurity A

Aminonitrophenolpropanediol

D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol, ≥ 98.0%

716-61-0

C9H12O4N2

C9H13N2O4

HOCH2CHNH2CHC6H4NO2OH

AMINE

Amino Alcohols

Asymmetric Synthesis

Organic Building Blocks

Optical Resolution

Chiral Building Blocks

for Resolution of Acids