ChemicalBook > CAS DataBase List > D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

Product Name
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
CAS No.
716-61-0
Chemical Name
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
Synonyms
(1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL;ChloromycinbaseL-base;levoamine;Chloromycin base;L-BASE (AMINODIOL);chloramphenicolbase;D(-)Threo-1-(4-nitro;Chloramphenicol impurity D;Chloramphenicol Impurity 1;Chloramphenicol Impurity A
CBNumber
CB6452870
Molecular Formula
C9H12N2O4
Formula Weight
212.2
MOL File
716-61-0.mol
More
Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Property

Melting point:
163-165 °C(lit.)
Boiling point:
352.03°C (rough estimate)
Density 
1.3136 (rough estimate)
refractive index 
-30.5 ° (C=1, 6mol/L HCl)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Water Solubility 
almost transparency in hot Water
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.98±0.45(Predicted)
form 
Powder
color 
Light yellow
optical activity
[α]25/D 30°, c = 1 in 6 M HCl
InChIKey
OCYJXSUPZMNXEN-RKDXNWHRSA-N
More
Less

Safety

Hazard Codes 
Xn,T
Risk Statements 
22-36/37/38-45
Safety Statements 
26-45-53-22
RIDADR 
UN 3259 8/PG 3
WGK Germany 
3
RTECS 
TY3100000
HS Code 
29221990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A70704
Product name
(1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity
99%
Packaging
10g
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
A70704
Product name
(1R,2R)-(?)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity
99%
Packaging
25g
Price
$146
Updated
2024/03/01
TCI Chemical
Product number
A1017
Product name
D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity
>98.0%(T)
Packaging
25g
Price
$79
Updated
2024/03/01
TCI Chemical
Product number
A1017
Product name
D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity
>98.0%(T)
Packaging
500g
Price
$689
Updated
2024/03/01
TRC
Product number
A622680
Product name
D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Packaging
50g
Price
$240
Updated
2021/12/16
More
Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

Uses

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol may be used in the preparation of (1R,2R)-(-)-2-dimethylamino-1-(4-nitrophenyl)-1,3-propanediol via N,N-dimethylation. It may also be used as a starting material to synthesize (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothioeyanate [(R,R)-DANI].

Uses

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.

Definition

ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Preparation Products And Raw materials

Raw materials

Propiophenone

Preparation Products

Potassium heptadecafluoro-1-octanesulfonate
More
Less

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Suppliers

Americas 1 Belgium 1 Canada 1 China 171 Europe 4 Germany 3 India 7 Japan 2 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 10 United States 23 Global 226
Ningbo Enzyme Chemical Co., LTD
Tel
0574-87730716-654 13819816642
Email
chngsi.liu@enzymaster.com
Country
China
ProdList
37
Advantage
58
Yancheng Huahong Chemical Co., Ltd.
Tel
15366451979
Email
sales@huahongchem.com
Country
China
ProdList
23
Advantage
58
Ningbo biermann pharmaceutical technology co., LTD
Tel
0571-82572971 13736400971
Fax
0574-87703432
Email
bichem.sales01@bichem.cn
Country
China
ProdList
47
Advantage
58
Beijing Bainiannuan Sci.&Tec. Co., Ltd
Tel
10-51765162 13240490036
Fax
+86-10-51765262
Email
marymeng@bdnchem.com
Country
China
ProdList
33
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Yaqee Industrial Corporation Limited
Tel
+86-561-5269788, 5209788
Fax
+86-561-5209268
Country
China
ProdList
40
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18089
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8613162137806 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9746
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9452
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9907
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13359
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 18232719690
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
398
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5943
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9972
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
ShangHai Angti Biotechnology Co., Ltd.
Tel
13764913901
Fax
-
Email
info@angtibio.com
Country
China
ProdList
4573
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
More
Less

View Lastest Price from D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL manufacturers

Hebei Duling International Trade Co. LTD
Product
D(-)Threo-1-(4-nitrophenyl)-2-amino-1,3-propanediol 716-61-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000tons
Release date
2022-10-13
Hebei Yanxi Chemical Co., Ltd.
Product
ChloromycinbaseL-base 716-61-0
Price
US $10.00-3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
15 tons
Release date
2023-09-27
Hebei Guanlang Biotechnology Co., Ltd.
Product
ChloromycinbaseL-base 716-61-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-09

716-61-0, D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOLRelated Search:

Chloramphenicol palmitate D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL Chloramphenicol sodium succinate Eusynthomycin Chloramphenicol (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol 2-Amino-1,3-propanediol Nitrophenol 2-Amino-1-(4-nitrophenyl)-1,3-propanediol CHLORAMPHENICOL 1-O-BETA-D-GALACTOPYRANOSIDE (1R,2R)-B13 BROMAMPHENICOL CHLORAMPHENICOL (D5) CHLORAMPHENICOL-ALCOHOL L-(+)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL BOC-(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL FMOC-(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL D-THREO-[DICHLOROACETYL-1-14C]-CHLORAMPHENICOL

  • ChloromycinbaseL-base
  • D-(-)-THREO-2-AMINO-1-(4-NITRO
  • (1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol
  • [1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
  • (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96%
  • (1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
  • (1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR
  • (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99%
  • (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96%
  • (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride
  • L-BASE (AMINODIOL)
  • <small>D</small>-(-)-<i>threo</i>-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
  • (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay)
  • d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol
  • levoamine
  • Chloromycin base
  • 2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)-
  • chloramphenicolbase
  • Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
  • (1R,2R)-(-)-2-Amino-1-(4-nitrophenyL
  • D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
  • D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL
  • CHLORAMPHENICOL-WATER SOLUBLE
  • (1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL
  • (1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
  • (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL
  • CHLORAMPHENICOL BASE CRYSTALLINE
  • (1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99%
  • D(-)Threo-1-(4-nitro-phenyl)-2
  • 1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)-
  • D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE
  • (1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL
  • D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol
  • (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
  • (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol nitrate
  • Chloramphenicol impurity D
  • (D)-(-)-threo-2-Amino-1-(4-nitrophe
  • Chloramphenicol Impurity 1 (D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol)
  • D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol &gt
  • Chloramphenicol Impurity 1
  • D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL USP/EP/BP
  • D(-)Threo-1-(4-nitro
  • (1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-aminium
  • D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol/D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
  • Chloramphenicol Impurity A
  • Aminonitrophenolpropanediol
  • D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol, ≥ 98.0%
  • 716-61-0
  • C9H12O4N2
  • C9H13N2O4
  • HOCH2CHNH2CHC6H4NO2OH
  • AMINE
  • Amino Alcohols
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Optical Resolution
  • Chiral Building Blocks
  • for Resolution of Acids