5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE

Product Name: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE
CAS No.: 131084-55-4
Chemical Name: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE
Synonyms: 100186;5-Chloro-6-azaindole;5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE;1H-PYRROLO[3,2-C]PYRIDIN,5-CHLORO-;1H-Pyrrolo[2,3-c]pyridine, 5-chloro-
CBNumber: CB02452429
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 131084-55-4.mol

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5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Property

Boiling point:: 335.8±22.0 °C(Predicted)
Density: 1.425
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 13.75±0.40(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C7H5ClN2/c8-7-3-5-1-2-9-6(5)4-10-7/h1-4,9H
InChIKey: XAIYMAHUJMVDHR-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC2C=CNC1=2
CAS DataBase Reference: 131084-55-4

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C422190
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 500mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: X9786
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 1g
Price: $91
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 500mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43579
Product name: 5-Chloro-1H-pyrrolo[2,3-c]pyridine
Packaging: 100mg
Price: $65
Updated: 2021/12/16

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5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Chemical Properties,Usage,Production

Uses

5-Chloro-1H-pyrrolo[2,3-c]pyridine is a versatile building block in chemical synthesis, commonly utilized in the pharmaceutical and agrochemical industries for the production of various biologically active compounds.

Synthesis

142078-36-2

131084-55-4

Using 2-(2-chloro-5-nitropyridin-4-yl)-N,N-dimethylvinyl-1-amine (221.2, 1.0 g, 4.4 mmol, 1.0 eq.) as starting material, it was dissolved in acetic acid (10 mL) at room temperature. Subsequently, iron powder (1.2 g, 22.0 mmol, 5.0 eq.) was added to this solution. The reaction mixture was heated to 90 °C and the reaction was stirred at this temperature for 2 hours. Upon completion of the reaction, sodium carbonate solution was slowly added to the reaction mixture to neutralize the reaction system, followed by extraction with ethyl acetate. All organic layers were combined, washed with brine solution to remove water-soluble impurities, and then the organic phase was dried with anhydrous sodium sulfate. After drying, the solvent was removed by concentration under reduced pressure to give the crude product. The crude product was further purified by column chromatography using a hexane solution of 30% ethyl acetate as eluent to give the target compound 5-chloro-1H-pyrrolo[2,3-c]pyridine (221.3, 0.65 g, 96.98% yield). Mass spectrometry (electrospray ionization): m/z 153.47 [M + H]+.

References

[1] Patent: WO2018/71794, 2018, A1. Location in patent: Paragraph 001020; 001022
[2] Patent: WO2010/42337, 2010, A1. Location in patent: Page/Page column 42; 43

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE Suppliers

China 155 India 4 Switzerland 2 United Kingdom 2 United States 10 Global 173

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View Lastest Price from 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE manufacturers

Career Henan Chemical Co

Product: 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE 131084-55-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-06-21

131084-55-4, 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINERelated Search:

6-Chloro-1,3-dihydro-2H-pyrrolo[3,2-c]pyridin-2-one 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 5-CHLORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 5-chloro- 5-CHLORO (1H)INDAZOLE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5-Chloro-6-azaindole-3-carboxaldehyde 5-Chloro-1H-pyrazolo[4,3-b]pyridine 5-Chloro-1,2,3,4-tetrahydroisoquinoline 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE 5-Chloro-[1,2,4]triazolo[1,5-a]pyridine 5-CHLORO-3-HYDROXY (1H)INDAZOLE 5-CHLORO-1H-INDOL-3-METHYLAMINE 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid 5-Chloro-1,3,4-thiadiazol-2-ylamine 6-Chloro-3H-1,2,3-triazolo[4,5-c]pyridine 5-Chloro-7-azaindole-3-carboxaldehyde 5-Chloro-7-azaindole-3-carboxylic acid Methyl ester

5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE

5-Chloro-6-azaindole

1H-Pyrrolo[2,3-c]pyridine, 5-chloro-

1H-PYRROLO[3,2-C]PYRIDIN,5-CHLORO-

100186

131084-55-4

131085-55-4

Heterocycle-Pyridine series