5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE
- Product Name
- 5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE
- CAS No.
- 148214-56-6
- Chemical Name
- 5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE
- Synonyms
- 5-Bromo-2-methoxypyrimidin-4-amine;4-Pyrimidinamine, 5-bromo-2-methoxy-;5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE;5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE ISO 9001:2015 REACH
- CBNumber
- CB02453219
- Molecular Formula
- C5H6BrN3O
- Formula Weight
- 204.02
- MOL File
- 148214-56-6.mol
5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE Property
- Melting point:
- 134-136 °C
- Boiling point:
- 332.3±45.0 °C(Predicted)
- Density
- 1.723±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 3.35±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B711150
- Product name
- 5-Bromo-2-methoxypyrimidin-4-amine
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- B12842
- Product name
- 5-Bromo-2-methoxypyrimidin-4-amine
- Purity
- 95%
- Packaging
- 500mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FB142198
- Product name
- 5-Bromo-2-methoxypyrimidin-4-ylamine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B12842
- Product name
- 5-Bromo-2-methoxypyrimidin-4-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- W3237
- Product name
- 5-Bromo-2-methoxypyrimidin-4-ylamine
- Packaging
- 1g
- Price
- $359
- Updated
- 2021/12/16
5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE Chemical Properties,Usage,Production
Synthesis
124-41-4
205672-25-9
148214-56-6
To a methanolic (1 L) suspension of 5-bromo-2-chloropyrimidin-4-amine (137.3 g, 658 mmol) was added sodium methanolate (83.5 g, 1.54 mol) in batches. The reaction mixture was stirred under reflux conditions for 2 hours. Upon completion of the reaction, the mixture was concentrated to about 400 mL and poured into saturated aqueous ammonium chloride solution (1.2 L). After stirring for 15 minutes, the aqueous layer was extracted with ethyl acetate. The combined organic layers were washed with brine, dried over anhydrous sodium sulfate, filtered and concentrated to give 5-bromo-2-methoxypyrimidin-4-amine (133.7 g, 99.4% yield).
References
[1] Patent: WO2015/155042, 2015, A1. Location in patent: Page/Page column 24; 25
[2] Patent: WO2016/166255, 2016, A1. Location in patent: Page/Page column 29
5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE manufacturers
- Product
- 5-BROMO-2-METHOXYPYRIMIDIN-4-YLAMINE 148214-56-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-02