ChemicalBook > CAS DataBase List > TCS 46B

TCS 46B

Product Name
TCS 46B
CAS No.
302799-86-6
Chemical Name
TCS 46B
Synonyms
TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
CBNumber
CB02453446
Molecular Formula
C22H23N3O
Formula Weight
345.44
MOL File
302799-86-6.mol
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TCS 46B Property

Boiling point:
440.4±38.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
pka
11.51±0.30(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2782
Product name
TCS46b
Purity
≥98%(HPLC)
Packaging
10
Price
$179
Updated
2021/12/16
Tocris
Product number
2782
Product name
TCS46b
Purity
≥98%(HPLC)
Packaging
50
Price
$662
Updated
2021/12/16
TRC
Product number
T012625
Product name
TCS46b
Packaging
25mg
Price
$265
Updated
2021/12/16
Usbiological
Product number
466895
Product name
TCS 46b
Packaging
10mg
Price
$418
Updated
2021/12/16
Usbiological
Product number
256882
Product name
TCS 46b
Packaging
10mg
Price
$432
Updated
2021/12/16
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TCS 46B Chemical Properties,Usage,Production

Uses

TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.

Biological Activity

Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.

TCS 46B Preparation Products And Raw materials

Raw materials

Preparation Products

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TCS 46B Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4575
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7295
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Taizhou Nanfeng Pharmaceutical Research Institute
Tel
18616377689
Email
nanfengdrug@163.com
Country
China
ProdList
20000
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4013
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44806
Advantage
58

302799-86-6, TCS 46BRelated Search:


  • TCS 46B
  • 1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one
  • 2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
  • 302799-86-6