TCS 46B

Product Name: TCS 46B
CAS No.: 302799-86-6
Chemical Name: TCS 46B
Synonyms: TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
CBNumber: CB02453446
Molecular Formula: C22H23N3O
Formula Weight: 345.44
MOL File: 302799-86-6.mol

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TCS 46B Property

Boiling point:: 440.4±38.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
form: Powder
pka: 11.51±0.30(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2782
Product name: TCS46b
Purity: ≥98%(HPLC)
Packaging: 10
Price: $179
Updated: 2021/12/16

Tocris

Product number: 2782
Product name: TCS46b
Purity: ≥98%(HPLC)
Packaging: 50
Price: $662
Updated: 2021/12/16

TRC

Product number: T012625
Product name: TCS46b
Packaging: 25mg
Price: $265
Updated: 2021/12/16

Usbiological

Product number: 466895
Product name: TCS 46b
Packaging: 10mg
Price: $418
Updated: 2021/12/16

Usbiological

Product number: 256882
Product name: TCS 46b
Packaging: 10mg
Price: $432
Updated: 2021/12/16

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TCS 46B Chemical Properties,Usage,Production

Uses

TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.

Biological Activity

Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.

TCS 46B Preparation Products And Raw materials

Raw materials

Preparation Products

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TCS 46B Suppliers

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302799-86-6, TCS 46BRelated Search:

N-BUTYL-3-PHENYLPROP-2-YN-1-AMINE TCS 46B

TCS 46B

1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one

2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-

302799-86-6