COMPOUND 401

Product Name: COMPOUND 401
CAS No.: 168425-64-7
Chemical Name: COMPOUND 401
Synonyms: CS-315;Morpholino a;Compound 401, >=98%;COMPOUND401;COMPOUND-401;Compound 401, 10 mM in DMSO;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-
CBNumber: CB02458229
Molecular Formula: C16H15N3O2
Formula Weight: 281.31
MOL File: 168425-64-7.mol

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COMPOUND 401 Property

Melting point:: 184-186℃ (ethanol )
Boiling point:: 456.9±55.0 °C(Predicted)
Density: 1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: Store at RT
solubility: DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming)
pka: 1.01±0.20(Predicted)
form: powder to crystal
color: White to Light yellow
CAS DataBase Reference: 168425-64-7

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Safety

HS Code: 2934.99.4400

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2537
Product name: 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
Purity: >98.0%(GC)
Packaging: 10mg
Price: $83
Updated: 2024/03/01

TCI Chemical

Product number: M2537
Product name: 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
Purity: >98.0%(GC)
Packaging: 50mg
Price: $292
Updated: 2024/03/01

Cayman Chemical

Product number: 21769
Product name: Compound 401
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21769
Product name: Compound 401
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 21769
Product name: Compound 401
Packaging: 10mg
Price: $153
Updated: 2024/03/01

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COMPOUND 401 Chemical Properties,Usage,Production

Uses

Compound 401 is a selective inhibitor of DNA-PK and FRAP.

Biological Activity

Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC 50 values are 0.28 and 5.3 μ M respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC 50 values are all > 100 μ M). Induces apoptosis in vitro .

COMPOUND 401 Preparation Products And Raw materials

Raw materials

Preparation Products

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COMPOUND 401 Suppliers

Americas 1 China 59 Europe 1 India 2 Japan 1 United Kingdom 1 United States 15 Global 80

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

168425-64-7, COMPOUND 401Related Search:

G-401 COMPOUND 401

2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one

4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-

2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one

2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one

Compound 401, >=98%

2-Morpholino-4<i>H</i>-pyrimido[2,1-<i>a</i>]isoquinolin-4-one

CS-315

COMPOUND401;COMPOUND-401

2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one&gt

Morpholino a

DNA-PK,Compound401,DNA-dependent protein kinase,Compound-401,Compound 401,inhibit,Inhibitor

Compound 401, DNA-dependent protein kinase and mTOR inhibitor

Compound 401, 10 mM in DMSO

168425-64-7