ChemicalBook > CAS DataBase List > (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

Product Name
(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
CAS No.
134234-12-1
Chemical Name
(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
Synonyms
CP-101;CP 98113;CP 101606;1-((1S,2S);Traxoprodil;propan-2-yl);(+)-CP 101,606;Traxoprodil(CP-101,606);CP-101,606 >=98% (HPLC);CP-101;606;CP 101606;CP101606
CBNumber
CB02461182
Molecular Formula
C20H25NO3
Formula Weight
327.42
MOL File
134234-12-1.mol
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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Property

Boiling point:
534.4±50.0 °C(Predicted)
Density 
1.228
storage temp. 
2-8°C
solubility 
DMSO: ≥35mg/mL
pka
9.99±0.26(Predicted)
form 
powder
color 
white to tan
optical activity
[α]/D +50 to +60° (c=1, MeOH)
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Safety

Hazard Codes 
T,N
Risk Statements 
25-36-50
Safety Statements 
26-45-61
RIDADR 
2811
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
Ⅲ
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0053
Product name
CP-101,606
Purity
≥98% (HPLC)
Packaging
5mg
Price
$125
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0053
Product name
CP-101,606
Purity
≥98% (HPLC)
Packaging
25mg
Price
$526
Updated
2024/03/01
Sigma-Aldrich
Product number
5.04523
Product name
CP-101,606 - CAS 134234-12-1 - Calbiochem
Packaging
5mg
Price
$191
Updated
2022/05/15
Cayman Chemical
Product number
23884
Product name
(+)-CP 101,606
Purity
≥98%
Packaging
5mg
Price
$72
Updated
2024/03/01
Cayman Chemical
Product number
23884
Product name
(+)-CP 101,606
Purity
≥98%
Packaging
10mg
Price
$93
Updated
2024/03/01
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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Chemical Properties,Usage,Production

Uses

Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM.

Uses

CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries.

brand name

Traxoprodil is INN.

General Description

CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons.

Biochem/physiol Actions

Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Suppliers

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134234-12-1, (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOLRelated Search:

(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 4,4,5,5-TetraMethyl-2-(3-triphenylen-2-yl-phenyl)-[1,3,2]dioxaborolane Butyl acetate Ethyl acetate 1-isopropylpiperidin-4-ol 1-phenethylpiperidin-4-ol (1S,2S)-(+)-N-METHYLPSEUDOEPHEDRINE CHEMBRDG-BB 4003161 1-Phenethyl-4-phenyl-4-piperidinol 1-[(1S,2S)-2-HYDROXY-1-METHYL-2-(4-TRIISOPROPYLSILANYLOXY-PHENYL)-ETHYL]-4-PHENYL-PIPERIDIN-4-OL alpha-[1-(Butylmethylamino)ethyl]-benzyl alcohol 4-HYDROXY-1-PIPERIDINEETHANOL 96 (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

  • 1-((1S,2S)
  • -1-Hydroxy-1-(4-hydroxyphenyl)
  • propan-2-yl)
  • (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
  • CP 101606
  • 1-[(1S,2S)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-4-phenylpiperidin-4-ol
  • (1s,2s)-1-[4-[ hydroxylphenyl]- 2- ( 4-hydroxy-4-pheny1piperidino)-1- propanol
  • 1-((1S,2S)-1-Hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol
  • CP-101
  • CP-101;606;CP 101606;CP101606
  • [S-(R*,R*)]-4-Hydroxy-alpha-(4-hydroxyphenyl)-beta-methyl-4-phenyl-1-piperidineethanol
  • CP 98113
  • Traxoprodil
  • Traxoprodil(CP-101,606)
  • 1-Piperidineethanol, 4-hydroxy-α-(4-hydroxyphenyl)-β-methyl-4-phenyl-, (αS,βS)-
  • CP-101,606 >=98% (HPLC)
  • (+)-CP 101,606
  • iGluR,Ionotropic glutamate receptors,inhibit,Inhibitor,Traxoprodil
  • CP101606，CP101606/Traxoprodil,CO-98113(racemate)
  • 134234-12-1