Dimethyl hydroxymethylphosphonate
- Product Name
- Dimethyl hydroxymethylphosphonate
- CAS No.
- 24630-67-9
- Chemical Name
- Dimethyl hydroxymethylphosphonate
- Synonyms
- Dimethyl hydroxymethylphosphonate;Hydroxymethylphosphonic acid dimethyl ester;Phosphonic acid, P-(hydroxymethyl)-, dimethyl ester
- CBNumber
- CB02462149
- Molecular Formula
- C3H9O4P
- Formula Weight
- 140.07
- MOL File
- 24630-67-9.mol
Dimethyl hydroxymethylphosphonate Property
- Boiling point:
- 209℃
- Density
- 1.245
- Flash point:
- 80℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 12.73±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C3H9O4P/c1-6-8(5,3-4)7-2/h4H,3H2,1-2H3
- InChIKey
- OIERWUPLBOKSRB-UHFFFAOYSA-N
- SMILES
- P(CO)(=O)(OC)OC
- CAS DataBase Reference
- 24630-67-9(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- 097238
- Product name
- Dimethyl (hydroxymethyl)phosphonate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 097238
- Product name
- Dimethyl (hydroxymethyl)phosphonate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $178
- Updated
- 2021/12/16
- Product number
- AK105037
- Product name
- Dimethyl(hydroxymethyl)phosphonate
- Purity
- 91%
- Packaging
- 10g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 1882AB
- Product name
- Dimethyl(hydroxymethyl)phosphonate
- Packaging
- 1g
- Price
- $290
- Updated
- 2021/12/16
- Product number
- AK105037
- Product name
- Dimethyl(hydroxymethyl)phosphonate
- Purity
- 91%
- Packaging
- 25g
- Price
- $360
- Updated
- 2021/12/16
Dimethyl hydroxymethylphosphonate Chemical Properties,Usage,Production
Synthesis
50-00-0
868-85-9
24630-67-9
Under stirring conditions, dimethyl phosphite (10.0 mL, 109 mmol), triethylamine (1.5 mL, 10.9 mmol) and paraformaldehyde (3.26 g) were mixed. The mixture was heated in an oil bath (external temperature) at 100°C. After 2.5 hours of reaction, the mixture was cooled to room temperature and subsequently concentrated under vacuum. The residue was purified by fast column chromatography (eluent: ethyl acetate/methanol, 95:5, v/v) to afford dimethyl hydroxymethylphosphonate as a colorless oil (9.41 g, 62% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 4.32 (1H, br s), 3.95 (2H, d, J = 6 Hz), 3.83 (3H, s), 3.81 (3H, s); 31P{1H} NMR (400.1 MHz, CDCl3): δ 27.8; 13C NMR (100.6 MHz. CDCl3): δ 53.5, 56.0, 57.6.
References
[1] Journal of Polymer Science, Part A: Polymer Chemistry, 2012, vol. 50, # 12, p. 2432 - 2443
[2] Chemistry - A European Journal, 2009, vol. 15, # 9, p. 2064 - 2070
[3] Patent: WO2006/20779, 2006, A2. Location in patent: Page/Page column 77
[4] Organic Letters, 2012, vol. 14, # 18, p. 4798 - 4801
[5] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 3, p. 315 - 322
Dimethyl hydroxymethylphosphonate Preparation Products And Raw materials
Raw materials
Preparation Products
Dimethyl hydroxymethylphosphonate Suppliers
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View Lastest Price from Dimethyl hydroxymethylphosphonate manufacturers
- Product
- Dimethyl (hydroxymethyl)phosphonate 24630-67-9
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-25
- Product
- Dimethyl(hydroxymethyl)phosphonate 24630-67-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100kg
- Release date
- 2023-10-13
- Product
- Dimethyl hydroxymethylphosphonate 24630-67-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11